Publications by authors named "Matthew Dong"

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Cas12a-knock-in mice for multiplexed genome editing, disease modelling and immune-cell engineering.
Kaiyuan Tang, Liqun Zhou, Xiaolong Tian, Shao-Yu Fang, Erica Vandenbulcke, Matthew B Dong

Nat Biomed Eng· August 2025

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CTLA-4 tail fusion enhances CAR-T antitumor immunity.
Xiaoyu Zhou, Hanbing Cao, Shao-Yu Fang, Ryan D Chow, Kaiyuan Tang, Matthew B Dong

Nat Immunol· September 2023

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Human gene age dating reveals an early and rapid evolutionary construction of the adaptive immune system.
Li Zhang, Jonathan J Park, Matthew B Dong, Deanna Arsala, Shengqian Xia

Genome Biol Evol· May 2023

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CTLA-4 tail fusion enhances CAR-T anti-tumor immunity.
Xiaoyu Zhou, Hanbing Cao, Shao-Yu Fang, Ryan D Chow, Kaiyuan Tang, Matthew B Dong

bioRxiv· March 2023

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Cas12a/Cpf1 knock-in mice enable efficient multiplexed immune cell engineering.
Matthew B Dong, Kaiyuan Tang, Xiaoyu Zhou, Johanna Shen, Krista Chen

bioRxiv· March 2023

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Multiplexed LNP-mRNA vaccination against pathogenic coronavirus species.
Lei Peng, Zhenhao Fang, Paul A Renauer, Andrew McNamara, Jonathan J Park, Matthew B Dong

Cell Rep· August 2022

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Variant-specific vaccination induces systems immune responses and potent in vivo protection against SARS-CoV-2.
Lei Peng, Paul A Renauer, Arya Ökten, Zhenhao Fang, Jonathan J Park, Matthew B Dong

Cell Rep Med· May 2022

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A genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance CAR-T therapy.
Lupeng Ye, Jonathan J Park, Lei Peng, Quanjun Yang, Ryan D Chow, Matthew B Dong

Cell Metab· April 2022

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Tumor immunology CRISPR screening: present, past, and future.
Matthew B Dong, Kaiyuan Tang, Xiaoyu Zhou, Jingjia J Zhou, Sidi Chen

Trends Cancer· March 2022

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Monospecific and bispecific monoclonal SARS-CoV-2 neutralizing antibodies that maintain potency against B.1.617.
Lei Peng, Yingxia Hu, Madeleine C Mankowski, Ping Ren, Rita E Chen, Matthew B Dong

Nat Commun· March 2022

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High-content CRISPR screening.
Christoph Bock, Paul Datlinger, Florence Chardon, Matthew A Coelho, Matthew B Dong

Nat Rev Methods Primers· February 2022

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Monospecific and bispecific monoclonal SARS-CoV-2 neutralizing antibodies that maintain potency against B.1.617.
Lei Peng, Yingxia Hu, Madeleine C Mankowski, Ping Ren, Rita E Chen, Matthew B Dong

bioRxiv· December 2021

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CRISPR-GEMM Pooled Mutagenic Screening Identifies KMT2D as a Major Modulator of Immune Checkpoint Blockade.
Guangchuan Wang, Ryan D Chow, Lvyun Zhu, Zhigang Bai, Lupeng Ye, Matthew B Dong

Cancer Discov· December 2020

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Nonstructural Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity Factor Redirecting Host Protein Synthesis Machinery toward Viral RNA.
Shuai Yuan, Lei Peng, Jonathan J Park, Yingxia Hu, Swapnil C Devarkar, Matthew B Dong

Mol Cell· December 2020

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In vivo CRISPR screening in CD8 T cells with AAV-Sleeping Beauty hybrid vectors identifies membrane targets for improving immunotherapy for glioblastoma.
Lupeng Ye, Jonathan J Park, Matthew B Dong, Quanjun Yang, Ryan D Chow

Nat Biotechnol· November 2019

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Multiplexed activation of endogenous genes by CRISPRa elicits potent antitumor immunity.
Guangchuan Wang, Ryan D Chow, Zhigang Bai, Lvyun Zhu, Youssef Errami, Matthew B Dong

Nat Immunol· November 2019

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Ketorolac Use Shortens Hospital Length of Stay After Bariatric Surgery: a Single-Center 5-Year Experience.
Kamyar Hariri, Elizabeth Hechenbleikner, Matthew Dong, Subhash U Kini, Gustavo Fernandez-Ranvier

Obes Surg· August 2019

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Systematic Immunotherapy Target Discovery Using Genome-Scale In Vivo CRISPR Screens in CD8 T Cells.
Matthew B Dong, Guangchuan Wang, Ryan D Chow, Lupeng Ye, Lvyun Zhu

Cell· August 2019

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In vivo profiling of metastatic double knockouts through CRISPR-Cpf1 screens.
Ryan D Chow, Guangchuan Wang, Lupeng Ye, Adan Codina, Hyunu Ray Kim, Matthew B Dong

Nat Methods· May 2019

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Convergent Identification and Interrogation of Tumor-Intrinsic Factors that Modulate Cancer Immunity In Vivo.
Adan Codina, Paul A Renauer, Guangchuan Wang, Ryan D Chow, Jonathan J Park, Matthew B Dong

Cell Syst· February 2019

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Is bariatric surgery effective for co-morbidity resolution in the super-obese patients?
Kamyar Hariri, Daniela Guevara, Matthew Dong, Subhash U Kini, Daniel M Herron

Surg Obes Relat Dis· September 2018

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Mapping a functional cancer genome atlas of tumor suppressors in mouse liver using AAV-CRISPR-mediated direct in vivo screening.
Guangchuan Wang, Ryan D Chow, Lupeng Ye, Christopher D Guzman, Xiaoyun Dai, Matthew B Dong

Sci Adv· February 2018

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AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma.
Ryan D Chow, Christopher D Guzman, Guangchuan Wang, Florian Schmidt, Mark W Youngblood, Matthew B Dong

Nat Neurosci· October 2017

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Determinants of Divergent Adaptive Immune Responses after Airway Sensitization with Ligands of Toll-Like Receptor 5 or Toll-Like Receptor 9.
Linda M Lee, Ming Ji, Meenal Sinha, Matthew B Dong, Xin Ren

PLoS One· July 2017

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Choleduodenal fistula with gastric outlet obstruction.
Matthew Dong, Alfredo Daniel Guerron, Gareth Morris-Stiff, Sricharan Chalikonda

BMJ Case Rep· April 2016

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