Publications by authors named "Matthew Pokross"

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Bicyclic Heterocyclic Replacement of an Aryl Amide Leading to Potent and Kinase-Selective Adaptor Protein 2-Associated Kinase 1 Inhibitors.
Richard A Hartz, Vijay T Ahuja, Susheel J Nara, C M Vijaya Kumar, Raju K V L P Manepalli, Matthew Pokross

J Med Chem· March 2022

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Identification of RIPK3 Type II Inhibitors Using High-Throughput Mechanistic Studies in Hit Triage.
Amy C Hart, Lynn Abell, Junqing Guo, Michael E Mertzman, Ramesh Padmanabha, Matthew Pokross

ACS Med Chem Lett· March 2020

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The discovery of macrocyclic XIAP antagonists from a DNA-programmed chemistry library, and their optimization to give lead compounds with in vivo antitumor activity.
Benjamin A Seigal, William H Connors, Andrew Fraley, Robert M Borzilleri, Percy H Carter, Matthew E Pokross

J Med Chem· March 2015

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Dynamically optimizing experiment schedules of a laboratory robot system with simulated annealing.
Cristina Cabrera, Morgan Fine-Morris, Matthew Pokross, Kevin Kish, Stephen Michalczyk

J Lab Autom· December 2014

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Structural basis for the high-affinity binding of pyrrolotriazine inhibitors of p38 MAP kinase.
John S Sack, Kevin F Kish, Matthew Pokross, Dianlin Xie, Gerald J Duke

Acta Crystallogr D Biol Crystallogr· July 2008

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Design, synthesis, and anti-inflammatory properties of orally active 4-(phenylamino)-pyrrolo[2,1-f][1,2,4]triazine p38alpha mitogen-activated protein kinase inhibitors.
John Hynes, Alaric J Dyckman, Shuqun Lin, Stephen T Wrobleski, Hong Wu, Matthew Pokross

J Med Chem· January 2008

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Serendipitous discovery of novel bacterial methionine aminopeptidase inhibitors.
Artem G Evdokimov, Matthew Pokross, Richard L Walter, Marlene Mekel, Bobby L Barnett

Proteins· February 2007

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Engineering the catalytic domain of human protein tyrosine phosphatase beta for structure-based drug discovery.
Artem G Evdokimov, Matthew Pokross, Richard Walter, Marlene Mekel, Brooke Cox

Acta Crystallogr D Biol Crystallogr· December 2006

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Design and synthesis of a series of novel pyrazolopyridines as HIF-1alpha prolyl hydroxylase inhibitors.
Namal C Warshakoon, Shengde Wu, Angelique Boyer, Richard Kawamoto, Sean Renock, Matthew Pokross

Bioorg Med Chem Lett· November 2006

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Design and synthesis of substituted pyridine derivatives as HIF-1alpha prolyl hydroxylase inhibitors.
Namal C Warshakoon, Shengde Wu, Angelique Boyer, Richard Kawamoto, Justin Sheville, Matthew Pokross

Bioorg Med Chem Lett· November 2006

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Design and synthesis of novel N-sulfonyl-2-indole carboxamides as potent PPAR-gamma binding agents with potential application to the treatment of osteoporosis.
Corey R Hopkins, Steven V O'neil, Michael C Laufersweiler, Yili Wang, Matthew Pokross

Bioorg Med Chem Lett· November 2006

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Structure-based design, synthesis, and SAR evaluation of a new series of 8-hydroxyquinolines as HIF-1alpha prolyl hydroxylase inhibitors.
Namal C Warshakoon, Shengde Wu, Angelique Boyer, Richard Kawamoto, Justin Sheville, Matthew Pokross

Bioorg Med Chem Lett· November 2006

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A novel series of imidazo[1,2-a]pyridine derivatives as HIF-1alpha prolyl hydroxylase inhibitors.
Namal C Warshakoon, Shengde Wu, Angelique Boyer, Richard Kawamoto, Justin Sheville, Matthew Pokross

Bioorg Med Chem Lett· November 2006

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Structural basis for the fast maturation of Arthropoda green fluorescent protein.
Artem G Evdokimov, Matthew E Pokross, Nikolay S Egorov, Andrey G Zaraisky, Ilya V Yampolsky

EMBO Rep· October 2006

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Design and synthesis of potent, non-peptidic inhibitors of HPTPbeta.
Kande K D Amarasinghe, Artem G Evdokimov, Kevin Xu, Cynthia M Clark, Matthew B Maier, Matthew E Pokross

Bioorg Med Chem Lett· August 2006

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1,2,3,4-Tetrahydroisoquinolinyl sulfamic acids as phosphatase PTP1B inhibitors.
Sean R Klopfenstein, Artem G Evdokimov, Anny-Odile Colson, Neil T Fairweather, Jeffrey J Neuman, Matthew E Pokross

Bioorg Med Chem Lett· March 2006

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Similar modes of polypeptide recognition by export chaperones in flagellar biosynthesis and type III secretion.
Artem G Evdokimov, Jason Phan, Joseph E Tropea, Karen M Routzahn, Howard K Peters, Matthew Pokross

Nat Struct Biol· October 2003

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Mechanism of insulin sensitization by BMOV (bis maltolato oxo vanadium); unliganded vanadium (VO4) as the active component.
Kevin G Peters, Mike G Davis, Brian W Howard, Matthew Pokross, Vinit Rastogi

J Inorg Biochem· August 2003

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