Publications by authors named "Matthias Festag"

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Safety, Tissue Distribution, and Metabolism of LNA-Containing Antisense Oligonucleotides in Rats.
Fernando Romero-Palomo, Matthias Festag, Barbara Lenz, Simone Schadt, Andreas Brink

Toxicol Pathol· August 2021

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Pediatric Safety of Polysorbates in Drug Formulations.
Christina Kriegel, Matthias Festag, Ravuri S K Kishore, Dieter Roethlisberger, Georg Schmitt

Children (Basel)· December 2019

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Interspecies Variation of Outer Retina and Choriocapillaris Imaged With Optical Coherence Tomography.
Petr Soukup, Peter Maloca, Bernd Altmann, Matthias Festag, Elke-Astrid Atzpodien

Invest Ophthalmol Vis Sci· August 2019

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Assessment of Preclinical Liver and Skeletal Muscle Biomarkers Following Clofibrate Administration in Wistar Rats.
Pierre Maliver, Matthias Festag, Moritz Bennecke, Francois Christen, Balázs Bánfai

Toxicol Pathol· June 2017

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From the Cover: The Minipig is a Suitable Non-Rodent Model in the Safety Assessment of Single Stranded Oligonucleotides.
Annamaria Braendli-Baiocco, Matthias Festag, Kamille Dumong Erichsen, Robert Persson, Michael J Mihatsch

Toxicol Sci· May 2017

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Inhibition of EGF Uptake by Nephrotoxic Antisense Drugs In Vitro and Implications for Preclinical Safety Profiling.
Annie Moisan, Marcel Gubler, Jitao David Zhang, Yann Tessier, Kamille Dumong Erichsen, Matthias Festag

Mol Ther Nucleic Acids· March 2017

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Characterization of a re-engineered, mesothelin-targeted Pseudomonas exotoxin fusion protein for lung cancer therapy.
Frieder Bauss, Martin Lechmann, Ben-Fillippo Krippendorff, Roland Staack, Frank Herting, Matthias Festag

Mol Oncol· October 2016

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Vehicle Systems and Excipients Used in Minipig Drug Development Studies.
Margaret L Weaver, Anette Blak Grossi, Jorgen Schützsack, Joanna Parish, Jeanet Løgsted, Matthias Festag

Toxicol Pathol· April 2016

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Recommendations from a global cross-company data sharing initiative on the incorporation of recovery phase animals in safety assessment studies to support first-in-human clinical trials.
Fiona Sewell, Kathryn Chapman, Paul Baldrick, David Brewster, Alan Broadmeadow, Matthias Festag

Regul Toxicol Pharmacol· October 2014

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Genotoxicity testing of peptides: folate deprivation as a marker of exaggerated pharmacology.
Melanie Guérard, Andreas Zeller, Matthias Festag, Christine Schubert, Thomas Singer

Toxicol Appl Pharmacol· September 2014

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A global pharmaceutical company initiative: an evidence-based approach to define the upper limit of body weight loss in short term toxicity studies.
Kathryn Chapman, Fiona Sewell, Linda Allais, Jean-Luc Delongeas, Elizabeth Donald, Matthias Festag

Regul Toxicol Pharmacol· October 2013

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Assessment of the genotoxic potential of azidothymidine in the comet, micronucleus, and Pig-a assay.
Melanie Guérard, Julie Koenig, Matthias Festag, Stephen D Dertinger, Thomas Singer

Toxicol Sci· October 2013

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Morphologic and functional effects of gamma secretase inhibition on splenic marginal zone B cells.
Maria Cristina de Vera Mudry, Franziska Regenass-Lechner, Laurence Ozmen, Bernd Altmann, Matthias Festag

Int J Alzheimers Dis· January 2013

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A European pharmaceutical company initiative challenging the regulatory requirement for acute toxicity studies in pharmaceutical drug development.
Sally Robinson, Jean-Luc Delongeas, Elizabeth Donald, David Dreher, Matthias Festag

Regul Toxicol Pharmacol· April 2008

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An in vitro embryotoxicity assay based on the disturbance of the differentiation of murine embryonic stem cells into endothelial cells. II. Testing of compounds.
Matthias Festag, Bruno Viertel, Pablo Steinberg, Claudia Sehner

Toxicol In Vitro· December 2007

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An in vitro embryotoxicity assay based on the disturbance of the differentiation of murine embryonic stem cells into endothelial cells. I: Establishment of the differentiation protocol.
Matthias Festag, Claudia Sehner, Pablo Steinberg, Bruno Viertel

Toxicol In Vitro· December 2007

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