Publications by authors named "Matthias T Stephan"

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Bedside manufacturing of engineered stem cells using gene therapy foam.
Carrie L Cummings, Sirkka B Stephan, Katelyn Fitzgerald, Matthias T Stephan

Mol Ther Methods Clin Dev· December 2025

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In vivo chimeric antigen receptor (CAR)-T cell therapy.
Adrian Bot, Andrew Scharenberg, Kevin Friedman, Lin Guey, Robert Hofmeister, Matthias T Stephan

Nat Rev Drug Discov· September 2025

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Author Correction: T cell-encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection.
Matthias T Stephan, Vladimir Ponomarev, Renier J Brentjens, Alex H Chang, Konstantin V Dobrenkov

Nat Med· June 2024

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Empowering patients from within: Emerging nanomedicines for in vivo immune cell reprogramming.
Matthias T Stephan

Semin Immunol· August 2021

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In Situ Programming of CAR T Cells.
Neha N Parayath, Matthias T Stephan

Annu Rev Biomed Eng· July 2021

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Nitinol thin films functionalized with CAR-T cells for the treatment of solid tumours.
Michael E Coon, Sirkka B Stephan, Vikas Gupta, Colin P Kealey, Matthias T Stephan

Nat Biomed Eng· February 2020

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Nanoparticles That Reshape the Tumor Milieu Create a Therapeutic Window for Effective T-cell Therapy in Solid Malignancies.
Fan Zhang, Sirkka B Stephan, Chibawanye I Ene, Tyrel T Smith, Eric C Holland, Matthias T Stephan

Cancer Res· July 2018

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In situ programming of leukaemia-specific T cells using synthetic DNA nanocarriers.
Tyrel T Smith, Sirkka B Stephan, Howell F Moffett, Laura E McKnight, Weihang Ji, Matthias T Stephan

Nat Nanotechnol· August 2017

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Biopolymers codelivering engineered T cells and STING agonists can eliminate heterogeneous tumors.
Tyrel T Smith, Howell F Moffett, Sirkka B Stephan, Cary F Opel, Amy G Dumigan, Matthias T Stephan

J Clin Invest· June 2017

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Synergistic innate and adaptive immune response to combination immunotherapy with anti-tumor antigen antibodies and extended serum half-life IL-2.
Eric F Zhu, Shuning A Gai, Cary F Opel, Byron H Kwan, Rishi Surana, Matthias T Stephan

Cancer Cell· April 2015

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Biopolymer implants enhance the efficacy of adoptive T-cell therapy.
Sirkka B Stephan, Alexandria M Taber, Ilona Jileaeva, Ericka P Pegues, Charles L Sentman, Matthias T Stephan

Nat Biotechnol· January 2015

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In vivo targeting of adoptively transferred T-cells with antibody- and cytokine-conjugated liposomes.
Yiran Zheng, Matthias T Stephan, S Annie Gai, Wuhbet Abraham, Adrianne Shearer

J Control Release· December 2013

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Synapse-directed delivery of immunomodulators using T-cell-conjugated nanoparticles.
Matthias T Stephan, Sirkka B Stephan, Peter Bak, Jianzhu Chen, Darrell J Irvine

Biomaterials· August 2012

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Enhancing Cell therapies from the Outside In: Cell Surface Engineering Using Synthetic Nanomaterials.
Matthias T Stephan, Darrell J Irvine

Nano Today· June 2011

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Interbilayer-crosslinked multilamellar vesicles as synthetic vaccines for potent humoral and cellular immune responses.
James J Moon, Heikyung Suh, Anna Bershteyn, Matthias T Stephan, Haipeng Liu

Nat Mater· March 2011

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Concurrent visualization of trafficking, expansion, and activation of T lymphocytes and T-cell precursors in vivo.
Il-Kang Na, John C Markley, Jennifer J Tsai, Nury L Yim, Bradley J Beattie, Matthias T Stephan

Blood· September 2010

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Therapeutic cell engineering with surface-conjugated synthetic nanoparticles.
Matthias T Stephan, James J Moon, Soong Ho Um, Anna Bershteyn, Darrell J Irvine

Nat Med· September 2010

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Aberrant tissue localization of fungus-specific CD4+ T cells in IL-10-deficient mice.
Amariliz Rivera, Nichole Collins, Matthias T Stephan, Lauren Lipuma, Ingrid Leiner

J Immunol· July 2009

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Erythroid-specific human factor IX delivery from in vivo selected hematopoietic stem cells following nonmyeloablative conditioning in hemophilia B mice.
Alex H Chang, Matthias T Stephan, Leszek Lisowski, Michel Sadelain

Mol Ther· October 2008

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T cell-encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection.
Matthias T Stephan, Vladimir Ponomarev, Renier J Brentjens, Alex H Chang, Konstantin V Dobrenkov

Nat Med· December 2007

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Stem cell-derived erythroid cells mediate long-term systemic protein delivery.
Alex H Chang, Matthias T Stephan, Michel Sadelain

Nat Biotechnol· August 2006

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