Publications by authors named "Meera Modi"

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Intravenous Delivery of a Gene Therapy Vector that Expresses an Antitransferrin Receptor 1 Nanobody-I2S Fusion Protein Rescued Central Nervous System Lysosomal Burden in Mucopolysaccharidosis II Mice.
Wanida Ruangsiriluk, Sarah Melissa P Jacobo, Andrea Iskenderian, Meera Modi, Nancy Chen

Hum Gene Ther· December 2025

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Phenotypic rescue via mTOR inhibition in neuron-specific Pten knockout mice reveals AKT and mTORC1-site specific changes.
Angelica D'Amore, Maria Sundberg, Rui Lin, Ella T Lubbers, Kellen D Winden, Meera Modi

Mol Psychiatry· July 2025

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Radiosynthesis and in vivo evaluation of [F]BEAN as a potential mitochondria-based PET biomarker for metabolic disorders.
Charalambos Kaittanis, Hyunjung Kim, Tyler Teceno, Yoann Petibon, Ashley Knight, Meera Modi

Bioorg Med Chem Lett· May 2025

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Advancing clinical development for neuronopathic Hunter syndrome through a quantitatively-driven reverse translation framework.
Robert D Latzman, Olivia Campagne, Meera E Modi, Marta Karas, C J Malanga

Clin Transl Sci· April 2024

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Seizure reduction in TSC2-mutant mouse model by an mTOR catalytic inhibitor.
Sameer C Dhamne, Meera E Modi, Audrey Gray, Simone Bonazzi, Lucas Craig

Ann Clin Transl Neurol· October 2023

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GENE TARGET: A framework for evaluating Mendelian neurodevelopmental disorders for gene therapy.
Maya Chopra, Meera E Modi, Kira A Dies, Nancy L Chamberlin, Elizabeth D Buttermore

Mol Ther Methods Clin Dev· December 2022

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Shifted phase of EEG cross-frequency coupling in individuals with Phelan-McDermid syndrome.
Michael G Mariscal, Elizabeth Berry-Kravis, Joseph D Buxbaum, Lauren E Ethridge, Rajna Filip-Dhima, Meera E Modi

Mol Autism· April 2021

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Phenotypic Screen with TSC-Deficient Neurons Reveals Heat-Shock Machinery as a Druggable Pathway for mTORC1 and Reduced Cilia.
Alessia Di Nardo, Isadora Lenoël, Kellen D Winden, Alina Rühmkorf, Meera E Modi

Cell Rep· June 2020

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Tau: A Novel Entry Point for mTOR-Based Treatments in Autism Spectrum Disorder?
Meera E Modi, Mustafa Sahin

Neuron· May 2020

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Auditory Processing of Speech and Tones in Children With Tuberous Sclerosis Complex.
Amanda M O'Brien, Laurie Bayet, Katherine Riley, Charles A Nelson, Mustafa Sahin, Meera E Modi

Front Integr Neurosci· April 2020

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A unified circuit for social behavior.
Meera E Modi, Mustafa Sahin

Neurobiol Learn Mem· November 2019

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A framework for the investigation of rare genetic disorders in neuropsychiatry.
Stephan J Sanders, Mustafa Sahin, Joseph Hostyk, Audrey Thurm, Sebastien Jacquemont, Meera E Modi

Nat Med· October 2019

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Electrographic spikes are common in wildtype mice.
Hannah Purtell, Sameer C Dhamne, Sarika Gurnani, Elizabeth Bainbridge, Meera E Modi

Epilepsy Behav· December 2018

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The Way Forward for Mechanism-Based Therapeutics in Genetically Defined Neurodevelopmental Disorders.
Meera E Modi, Mustafa Sahin

Clin Pharmacol Ther· October 2018

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Hyperactivity and Hypermotivation Associated With Increased Striatal mGluR1 Signaling in a Shank2 Rat Model of Autism.
Meera E Modi, Julie M Brooks, Edward R Guilmette, Mercedes Beyna, Radka Graf

Front Mol Neurosci· June 2018

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mGluR5 Modulation of Behavioral and Epileptic Phenotypes in a Mouse Model of Tuberous Sclerosis Complex.
Elyza Kelly, Samantha M Schaeffer, Sameer C Dhamne, Jonathan O Lipton, Lothar Lindemann, Meera E Modi

Neuropsychopharmacology· May 2018

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Replicable in vivo physiological and behavioral phenotypes of the null mutant mouse model of autism.
Sameer C Dhamne, Jill L Silverman, Chloe E Super, Stephen H T Lammers, Mustafa Q Hameed, Meera E Modi

Mol Autism· March 2018

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Translational use of event-related potentials to assess circuit integrity in ASD.
Meera E Modi, Mustafa Sahin

Nat Rev Neurol· March 2017

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Peripheral Administration of a Long-Acting Peptide Oxytocin Receptor Agonist Inhibits Fear-Induced Freezing.
Meera E Modi, Mark J Majchrzak, Kari R Fonseca, Angela Doran, Sarah Osgood

J Pharmacol Exp Ther· August 2016

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Oxytocin in the nucleus accumbens shell reverses CRFR2-evoked passive stress-coping after partner loss in monogamous male prairie voles.
Oliver J Bosch, Joanna Dabrowska, Meera E Modi, Zachary V Johnson, Alaine C Keebaugh

Psychoneuroendocrinology· February 2016

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Melanocortin Receptor Agonists Facilitate Oxytocin-Dependent Partner Preference Formation in the Prairie Vole.
Meera E Modi, Kiyoshi Inoue, Catherine E Barrett, Kara A Kittelberger, Daniel G Smith

Neuropsychopharmacology· July 2015

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Neonatal melanocortin receptor agonist treatment reduces play fighting and promotes adult attachment in prairie voles in a sex-dependent manner.
Catherine E Barrett, Meera E Modi, Billy C Zhang, Hasse Walum, Kiyoshi Inoue

Neuropharmacology· October 2014

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Aerosolized oxytocin increases cerebrospinal fluid oxytocin in rhesus macaques.
Meera E Modi, Fawn Connor-Stroud, Rainer Landgraf, Larry J Young, Lisa A Parr

Psychoneuroendocrinology· July 2014

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Advancing the discovery of medications for autism spectrum disorder using new technologies to reveal social brain circuitry in rodents.
Martien J Kas, Meera E Modi, Michael D Saxe, Daniel G Smith

Psychopharmacology (Berl)· March 2014

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Intranasal oxytocin selectively attenuates rhesus monkeys' attention to negative facial expressions.
Lisa A Parr, Meera Modi, Erin Siebert, Larry J Young

Psychoneuroendocrinology· September 2013

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