Publications by authors named "Mehran Yazdanian"

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Overview of Determination of Biopharmaceutical Properties for Development Candidate Selection.
Mehran Yazdanian

Curr Protoc· November 2023

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Commentary: Why Pharmaceutical Scientists in Early Drug Discovery Are Critical for Influencing the Design and Selection of Optimal Drug Candidates.
Margaret S Landis, Shobha Bhattachar, Mehran Yazdanian, John Morrison

AAPS PharmSciTech· January 2018

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Evolution of Choice of Solubility and Dissolution Media After Two Decades of Biopharmaceutical Classification System.
Nadia Bou-Chacra, Katherine Jasmine Curo Melo, Ivan Andrés Cordova Morales, Erika S Stippler, Filippos Kesisoglou, Mehran Yazdanian

AAPS J· July 2017

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Lipophilicity in Drug Development: Too Much or Not Enough?
Christel A S Bergström, Mehran Yazdanian

AAPS J· September 2016

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The Effect of Excipients on the Permeability of BCS Class III Compounds and Implications for Biowaivers.
Alan Parr, Ismael J Hidalgo, Chris Bode, William Brown, Mehran Yazdanian

Pharm Res· January 2016

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Overview of determination of biopharmaceutical properties for development candidate selection.
Mehran Yazdanian

Curr Protoc Pharmacol· March 2013

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CEP-32496: a novel orally active BRAF(V600E) inhibitor with selective cellular and in vivo antitumor activity.
Joyce James, Bruce Ruggeri, Robert C Armstrong, Martin W Rowbottom, Susan Jones-Bolin, Mehran Yazdanian

Mol Cancer Ther· April 2012

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2,7-Disubstituted-pyrrolotriazine kinase inhibitors with an unusually high degree of reactive metabolite formation.
Kevin J Wells-Knecht, Gregory R Ott, Mangeng Cheng, Gregory J Wells, Henry J Breslin, Mehran Yazdanian

Chem Res Toxicol· November 2011

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A comprehensive study demonstrating that p-glycoprotein function is directly affected by changes in pH: implications for intestinal pH and effects on drug absorption.
Pallabi Mitra, Kenneth Audus, Gervan Williams, Mehran Yazdanian, Deborah Galinis

J Pharm Sci· October 2011

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Discovery and characterization of 6-{4-[3-(R)-2-methylpyrrolidin-1-yl)propoxy]phenyl}-2H-pyridazin-3-one (CEP-26401, irdabisant): a potent, selective histamine H3 receptor inverse agonist.
Robert L Hudkins, Rita Raddatz, Ming Tao, Joanne R Mathiasen, Lisa D Aimone, Mehran Yazdanian

J Med Chem· July 2011

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George Zografi: researcher and educator.
Paul M Bummer, Mehran Yazdanian

Pharm Res· October 2006

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Tetrazole compounds: the effect of structure and pH on Caco-2 cell permeability.
Amber M Young, Kenneth L Audus, John Proudfoot, Mehran Yazdanian

J Pharm Sci· April 2006

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The "high solubility" definition of the current FDA Guidance on Biopharmaceutical Classification System may be too strict for acidic drugs.
Mehran Yazdanian, Katherine Briggs, Corinne Jankovsky, Amale Hawi

Pharm Res· February 2004

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A structure-permeability study of small drug-like molecules.
Thomas Fichert, Mehran Yazdanian, John R Proudfoot

Bioorg Med Chem Lett· February 2003

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