Publications by authors named "Michael A Farrell"

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The CALHM1 blocker CGP37157 increases seizure severity during status epilepticus in adult mice.
Meghma Mitra, Amaya Sanz Rodriguez, Norman Delanty, Alan Beausang, Francesca M Brett, Michael A Farrell

Purinergic Signal· December 2025

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N6-methyladenosine (m6A) dysregulation contributes to network excitability in temporal lobe epilepsy.
Justine Mathoux, Marc-Michel Wilson, Sujithra Srinivas, Gabrielle Litovskich, Leticia Villalba Benito, Michael A Farrell

JCI Insight· July 2025

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Impact of JQ1 treatment on seizures, hippocampal gene expression, and gliosis in a mouse model of temporal lobe epilepsy.
Aileen Harnett, Justine Mathoux, Marc-Michel Wilson, Mona Heiland, Omar Mamad, Michael A Farrell

Eur J Neurosci· September 2024

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Immunoproteasome deficiency results in age-dependent development of epilepsy.
Hanna Leister, Felix F Krause, Beatriz Gil, Ruslan Prus, Inna Prus, Michael A Farrell

Brain Commun· January 2024

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CPEB4-CLOCK crosstalk during temporal lobe epilepsy.
Laura de Diego-Garcia, Gary P Brennan, Theresa Auer, Aida Menendez-Mendez, Alberto Parras, Michael A Farrell

Epilepsia· October 2023

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Anaplastic ganglioglioma-A diagnosis comprising several distinct tumour types.
Annekathrin Reinhardt, Kristin Pfister, Daniel Schrimpf, Damian Stichel, Felix Sahm, Michael A Farrell

Neuropathol Appl Neurobiol· December 2022

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Microvascular stabilization via blood-brain barrier regulation prevents seizure activity.
Chris Greene, Nicole Hanley, Cristina R Reschke, Avril Reddy, Maarja A Mäe, Michael A Farrell

Nat Commun· April 2022

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Polyadenylation of mRNA as a novel regulatory mechanism of gene expression in temporal lobe epilepsy.
Alberto Parras, Laura de Diego-Garcia, Mariana Alves, Edward Beamer, Giorgia Conte, Michael A Farrell

Brain· July 2020

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Disease-Specific Strains of α-Synuclein in Multiple System Atrophy and Parkinson's Disease: But Why?
Conor Fearon, Michael A Farrell

Mov Disord· May 2020

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Evaluation of the specificity of the central diagnostic criterion for chronic traumatic encephalopathy.
Jennifer Lorigan, Hugh Kearney, Bryan Grimes, Josephine Heffernan, Alan Beausang, Michael A Farrell

Ir J Med Sci· August 2019

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MicroRNA-22 Controls Aberrant Neurogenesis and Changes in Neuronal Morphology After Status Epilepticus.
Edward H Beamer, Jeronimo Jurado-Arjona, Eva M Jimenez-Mateos, James Morgan, Cristina R Reschke, Michael A Farrell

Front Mol Neurosci· December 2018

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Absence of 1p/19q codeletion in oligodendroglioma-like areas of pilocytic astrocytomas.
Beth Frazer, Hugh Kearney, Jane Cryan, Alan Beausang, Francesca Brett, Michael A Farrell

Clin Neuropathol· November 2018

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The DNA copy number landscape of a collision tumor.
Hugh Kearney, Jane B Cryan, Seamus Looby, Francesca M Brett, Michael A Farrell

Clin Neuropathol· August 2018

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The significance of BRAF V600E mutation status discordance between primary cutaneous melanoma and brain metastases: The implications for BRAF inhibitor therapy.
Enda J Hannan, Donal P O'Leary, Stephen P MacNally, Elaine W Kay, Michael A Farrell

Medicine (Baltimore)· December 2017

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Expression and function of the metabotropic purinergic P2Y receptor family in experimental seizure models and patients with drug-refractory epilepsy.
Mariana Alves, Rosa Gomez-Villafuertes, Norman Delanty, Michael A Farrell, Donncha F O'Brien

Epilepsia· September 2017

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A microRNA-129-5p/Rbfox crosstalk coordinates homeostatic downscaling of excitatory synapses.
Marek Rajman, Franziska Metge, Roberto Fiore, Sharof Khudayberdiev, Ayla Aksoy-Aksel, Michael A Farrell

EMBO J· June 2017

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Cerebrospinal fluid microRNAs are potential biomarkers of temporal lobe epilepsy and status epilepticus.
Rana Raoof, Eva M Jimenez-Mateos, Sebastian Bauer, Björn Tackenberg, Felix Rosenow, Michael A Farrell

Sci Rep· June 2017

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Potent Anti-seizure Effects of Locked Nucleic Acid Antagomirs Targeting miR-134 in Multiple Mouse and Rat Models of Epilepsy.
Cristina R Reschke, Luiz F Almeida Silva, Braxton A Norwood, Ketharini Senthilkumar, Gareth Morris, Michael A Farrell

Mol Ther Nucleic Acids· March 2017

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RNA sequencing of synaptic and cytoplasmic Upf1-bound transcripts supports contribution of nonsense-mediated decay to epileptogenesis.
Claire M Mooney, Eva M Jimenez-Mateos, Tobias Engel, Catherine Mooney, Mairead Diviney, Michael A Farrell

Sci Rep· January 2017

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Transient P2X7 Receptor Antagonism Produces Lasting Reductions in Spontaneous Seizures and Gliosis in Experimental Temporal Lobe Epilepsy.
Alba Jimenez-Pacheco, Miguel Diaz-Hernandez, Marina Arribas-Blázquez, Amaya Sanz-Rodriguez, Luis A Olivos-Oré, Michael A Farrell

J Neurosci· June 2016

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Rapid Clinical Course of Multiple Metastatic Cerebral Angiosarcoma.
Zaitun Zakaria, Kantharuby Tambirajoo, Mohammad Taufiq Sattar, Michael A Farrell

Turk Neurosurg· February 2016

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Autoregulated paracellular clearance of amyloid-β across the blood-brain barrier.
James Keaney, Dominic M Walsh, Tiernan O'Malley, Natalie Hudson, Darragh E Crosbie, Michael A Farrell

Sci Adv· September 2015

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Familial cerebral amyloid angiopathy due to the Iowa mutation in an Irish family.
Tzehow Mok, Albi J Chalissery, Susan Byrne, Lisa Costelloe, Leo Galvin, Michael A Farrell

Can J Neurol Sci· July 2014

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Migrating partial seizures of infancy: expansion of the electroclinical, radiological and pathological disease spectrum.
Amy McTague, Richard Appleton, Shivaram Avula, J Helen Cross, Mary D King, Michael A Farrell

Brain· May 2013

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CHOP regulates the p53-MDM2 axis and is required for neuronal survival after seizures.
Tobias Engel, Amaya Sanz-Rodgriguez, Eva M Jimenez-Mateos, Caoimhin G Concannon, Alba Jimenez-Pacheco, Michael A Farrell

Brain· February 2013

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