Publications by authors named "Michael D Winther"

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Improving prescribing: a feasibility study of pharmacogenetic testing with clinical decision support in primary healthcare in Singapore.
Helen Smith, Martin Dawes, Hagit Katzov-Eckert, Sarah Burrell, Sam Xin Hui, Michael D Winther

Fam Pract· August 2024

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Southeast Asian Pharmacogenomics Research Network (SEAPharm): Current Status and Perspectives.
Supatat Chumnumwat, Zen Huat Lu, Chonlaphat Sukasem, Michael David Winther, Francis R Capule

Public Health Genomics· May 2020

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Economic burden of adverse drug reactions and potential for pharmacogenomic testing in Singaporean adults.
Sze Ling Chan, Hong Yen Ng, Cynthia Sung, Alexandre Chan, Michael D Winther

Pharmacogenomics J· August 2019

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Genotype-guided versus traditional clinical dosing of warfarin in patients of Asian ancestry: a randomized controlled trial.
Nicholas L Syn, Andrea Li-Ann Wong, Soo-Chin Lee, Hock-Luen Teoh, James Wei Luen Yip, Michael D Winther

BMC Med· July 2018

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Pharmacogenomics in Asia: a systematic review on current trends and novel discoveries.
Hazel Xiaohui Ang, Sze Ling Chan, Levana L Sani, Clarissa Bernice Quah, Liam R Brunham, Michael D Winther

Pharmacogenomics· June 2017

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Prevalence and characteristics of adverse drug reactions at admission to hospital: a prospective observational study.
Sze Ling Chan, Xiaohui Ang, Levana L Sani, Hong Yen Ng, Michael D Winther

Br J Clin Pharmacol· December 2016

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Discovery of triazolone derivatives as novel, potent stearoyl-CoA desaturase-1 (SCD1) inhibitors.
Shaoyi Sun, Zaihui Zhang, Natalia Pokrovskaia, Sultan Chowdhury, Qi Jia, Michael D Winther

Bioorg Med Chem· February 2015

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Opportunities and challenges in developing stearoyl-coenzyme A desaturase-1 inhibitors as novel therapeutics for human disease.
Zaihui Zhang, Natalie A Dales, Michael D Winther

J Med Chem· June 2014

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Discovery of thiazolylpyridinone SCD1 inhibitors with preferential liver distribution and reduced mechanism-based adverse effects.
Shaoyi Sun, Zaihui Zhang, Vandna Raina, Natalia Pokrovskaia, Duanjie Hou, Michael D Winther

Bioorg Med Chem Lett· January 2014

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Systematic evaluation of amide bioisosteres leading to the discovery of novel and potent thiazolylimidazolidinone inhibitors of SCD1 for the treatment of metabolic diseases.
Shaoyi Sun, Zaihui Zhang, Vishnumurthy Kodumuru, Natalia Pokrovskaia, Julia Fonarev, Michael D Winther

Bioorg Med Chem Lett· January 2014

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Discovery of XEN445: a potent and selective endothelial lipase inhibitor raises plasma HDL-cholesterol concentration in mice.
Shaoyi Sun, Richard Dean, Qi Jia, Alla Zenova, Jing Zhong, Michael D Winther

Bioorg Med Chem· December 2013

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Pharmacological inhibition of stearoyl CoA desaturase in the skin induces atrophy of the sebaceous glands.
Josef G Meingassner, Heinrich Aschauer, Anthony P Winiski, Natalie Dales, David Yowe, Michael D Winther

J Invest Dermatol· August 2013

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Discovery of piperazin-1-ylpyridazine-based potent and selective stearoyl-CoA desaturase-1 inhibitors for the treatment of obesity and metabolic syndrome.
Zaihui Zhang, Shaoyi Sun, Vishnumurthy Kodumuru, Duanjie Hou, Shifeng Liu, Michael D Winther

J Med Chem· January 2013

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