Publications by authors named "Michael Jarosh"

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Correlation of Optical and Automated Patch Clamp Electrophysiology for Identification of Na1.7 Inhibitors.
Hongkang Zhang, Bryan D Moyer, Violeta Yu, Joseph G McGivern, Michael Jarosh

SLAS Discov· June 2020

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Discovery of a biarylamide series of potent, state-dependent Na1.7 inhibitors.
Laurie B Schenkel, Erin F DiMauro, Hanh N Nguyen, Nagasree Chakka, Bingfan Du, Michael Jarosh

Bioorg Med Chem Lett· August 2017

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Sulfonamides as Selective Na1.7 Inhibitors: Optimizing Potency and Pharmacokinetics While Mitigating Metabolic Liabilities.
Matthew M Weiss, Thomas A Dineen, Isaac E Marx, Steven Altmann, Alessandro Boezio, Michael Jarosh

J Med Chem· July 2017

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Sulfonamides as Selective Na1.7 Inhibitors: Optimizing Potency, Pharmacokinetics, and Metabolic Properties to Obtain Atropisomeric Quinolinone (AM-0466) that Affords Robust in Vivo Activity.
Russell F Graceffa, Alessandro A Boezio, Jessica Able, Steven Altmann, Loren M Berry, Michael Jarosh

J Med Chem· July 2017

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Pharmacologic Characterization of AMG8379, a Potent and Selective Small Molecule Sulfonamide Antagonist of the Voltage-Gated Sodium Channel Na1.7.
Thomas J Kornecook, Ruoyuan Yin, Stephen Altmann, Xuhai Be, Virginia Berry, Michael Jarosh

J Pharmacol Exp Ther· July 2017

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Application of a Parallel Synthetic Strategy in the Discovery of Biaryl Acyl Sulfonamides as Efficient and Selective NaV1.7 Inhibitors.
Erin F DiMauro, Stephen Altmann, Loren M Berry, Howard Bregman, Nagasree Chakka, Michael Jarosh

J Med Chem· September 2016

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Aromatic nitration in liquid Ag0.51K0.42Na0.07NO3.
Mark Mascal, Lunxiang Yin, Ross Edwards, Michael Jarosh

J Org Chem· August 2008

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