Publications by authors named "Michael Pennington"

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Evaluation of the Clinical Safety of the Low-Cost Warburg Therapy for the Treatment of Patients With Advanced Cancers.
Peihua Lu, Tom Tsang, Michael S Badowski, Michael E Pennington, Linda C Meade-Tollin

Cancer Med· December 2024

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Treatment challenges of persistent ghost cell odontogenic carcinoma: a case report and literature review.
Ali Al-Sammak, Othman Rezki, Michael Pennington, Frances Manosca, Maria Cuevas-Nunez

Oral Surg Oral Med Oral Pathol Oral Radiol· October 2023

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Adeno-Associated virus 8 delivers an immunomodulatory peptide to mouse liver more efficiently than to rat liver.
Yuqing Wang, Ayrea Hurley, Marco De Giorgi, Mark R Tanner, Rong-Chi Hu, Michael W Pennington

PLoS One· April 2023

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A bioengineered probiotic for the oral delivery of a peptide Kv1.3 channel blocker to treat rheumatoid arthritis.
Yuqing Wang, Duolong Zhu, Laura C Ortiz-Velez, Jacob L Perry, Michael W Pennington

Proc Natl Acad Sci U S A· January 2023

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Computational design of peptides to target Na1.7 channel with high potency and selectivity for the treatment of pain.
Phuong T Nguyen, Hai M Nguyen, Karen M Wagner, Robert G Stewart, Vikrant Singh, Michael W Pennington

Elife· December 2022

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A Conjugate between Lqh-8/6, a Natural Peptide Analogue of Chlorotoxin, and Doxorubicin Efficiently Induces Glioma Cell Death.
Lucie Dardevet, Feten Najlaoui, Sonia Aroui, Mayeul Collot, Céline Tisseyre, Michael W Pennington

Biomedicines· October 2022

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Kv1.3 Channel Up-Regulation in Peripheral Blood T Lymphocytes of Patients With Multiple Sclerosis.
Ioannis Markakis, Ioannis Charitakis, Christine Beeton, Melpomeni Galani, Elpida Repousi, Michael W Pennington

Front Pharmacol· September 2021

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K 1.3 channels are novel determinants of macrophage-dependent endothelial dysfunction in angiotensin II-induced hypertension in mice.
Miguel A Olivencia, Marta Martínez-Casales, Diego A Peraza, Ana B García-Redondo, Gema Mondéjar-Parreño, Michael W Pennington

Br J Pharmacol· April 2021

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Biophysical basis for Kv1.3 regulation of membrane potential changes induced by P2X4-mediated calcium entry in microglia.
Hai M Nguyen, Jacopo di Lucente, Yi-Je Chen, Yanjun Cui, Rania H Ibrahim, Michael W Pennington

Glia· November 2020

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Modulation of Lymphocyte Potassium Channel K1.3 by Membrane-Penetrating, Joint-Targeting Immunomodulatory Plant Defensin.
Seow Theng Ong, Saumya Bajaj, Mark R Tanner, Shih Chieh Chang, Bankala Krishnarjuna, Michael W Pennington

ACS Pharmacol Transl Sci· August 2020

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Comprehensive engineering of the tarantula venom peptide huwentoxin-IV to inhibit the human voltage-gated sodium channel hNa1.7.
Robert A Neff, Mack Flinspach, Alan Gibbs, Amy Y Shih, Natali A Minassian, Michael W Pennington

J Biol Chem· January 2020

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Preclinical Efficacy of a Lipooligosaccharide Peptide Mimic Candidate Gonococcal Vaccine.
Sunita Gulati, Michael W Pennington, Andrzej Czerwinski, Darrick Carter, Bo Zheng

mBio· November 2019

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The molecular evolution of feathers with direct evidence from fossils.
Yanhong Pan, Wenxia Zheng, Roger H Sawyer, Michael W Pennington, Xiaoting Zheng

Proc Natl Acad Sci U S A· February 2019

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KCa1.1 and Kv1.3 channels regulate the interactions between fibroblast-like synoviocytes and T lymphocytes during rheumatoid arthritis.
Mark R Tanner, Michael W Pennington, Satendra S Chauhan, Teresina Laragione, Pércio S Gulko

Arthritis Res Ther· January 2019

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Synthesis, folding, structure and activity of a predicted peptide from the sea anemone Oulactis sp. with an ShKT fold.
Bankala Krishnarjuna, Jessica Villegas-Moreno, Michela L Mitchell, Agota Csoti, Steve Peigneur, Michael W Pennington

Toxicon· August 2018

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Peptide therapeutics from venom: Current status and potential.
Michael W Pennington, Andrzej Czerwinski, Raymond S Norton

Bioorg Med Chem· June 2018

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Targeting KCa1.1 Channels with a Scorpion Venom Peptide for the Therapy of Rat Models of Rheumatoid Arthritis.
Mark R Tanner, Michael W Pennington, Brayden H Chamberlain, Redwan Huq, Elizabeth J Gehrmann

J Pharmacol Exp Ther· May 2018

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Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer's disease.
Srikant Rangaraju, Eric B Dammer, Syed Ali Raza, Priyadharshini Rathakrishnan, Hailian Xiao, Michael W Pennington

Mol Neurodegener· May 2018

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Corrigendum to "Structure, folding and stability of a minimal homologue from Anemonia sulcata of the sea anemone potassium channel blocker ShK" [Peptides 99 (2018) 169-178].
Bankala Krishnarjuna, Christopher A MacRaild, Punnepalli Sunanda, Rodrigo A V Morales, Steve Peigneur, Michael W Pennington

Peptides· March 2018

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Structure, folding and stability of a minimal homologue from Anemonia sulcata of the sea anemone potassium channel blocker ShK.
Bankala Krishnarjuna, Christopher A MacRaild, Punnepalli Sunanda, Rodrigo A V Morales, Steve Peigneur, Michael W Pennington

Peptides· January 2018

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KCa1.1 channels regulate β-integrin function and cell adhesion in rheumatoid arthritis fibroblast-like synoviocytes.
Mark R Tanner, Michael W Pennington, Teresina Laragione, Pércio S Gulko, Christine Beeton

FASEB J· August 2017

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Reinvestigation of the biological activity of d-allo-ShK protein.
Bobo Dang, Sandeep Chhabra, Michael W Pennington, Raymond S Norton, Stephen B H Kent

J Biol Chem· July 2017

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Distribution and kinetics of the Kv1.3-blocking peptide HsTX1[R14A] in experimental rats.
Ralf Bergmann, Manja Kubeil, Kristof Zarschler, Sandeep Chhabra, Rajeev B Tajhya, Michael W Pennington

Sci Rep· June 2017

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A systems pharmacology-based approach to identify novel Kv1.3 channel-dependent mechanisms in microglial activation.
Srikant Rangaraju, Syed Ali Raza, Andrea Pennati, Qiudong Deng, Eric B Dammer, Michael W Pennington

J Neuroinflammation· June 2017

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The Single Disulfide-Directed β-Hairpin Fold. Dynamics, Stability, and Engineering.
Balasubramanyam Chittoor, Bankala Krishnarjuna, Rodrigo A V Morales, Christopher A MacRaild, Maiada Sadek, Michael W Pennington

Biochemistry· May 2017

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