Publications by authors named "Michael T Overgaard"

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Functional consequences of calmodulin variants identified among schizophrenia patients and controls.
Helene Halkjær Jensen, Malene Brohus, John W Hussey, Ana-Octavia Busuioc, Emil Drivsholm Iversen, Michael Toft Overgaard

Transl Psychiatry· November 2025

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To Fly, or Not to Fly, That Is the Question: A Deep Learning Model for Peptide Detectability Prediction in Mass Spectrometry.
Naim Abdul-Khalek, Mario Picciani, Omar Shouman, Reinhard Wimmer, Michael Toft Overgaard

J Proteome Res· June 2025

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Inositol 1,4,5-Trisphosphate Receptor 1 Gain-of-Function Increases the Risk for Cardiac Arrhythmias in Mice and Humans.
Bo Sun, Mingke Ni, Yanhui Li, Zhenpeng Song, Hui Wang, Michael Toft Overgaard

Circulation· March 2025

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A homo-FRET assay for patatin-specific proteolytic activity.
Lise Friis Christensen, Michael Toft Overgaard, Egon Bech Hansen, Simon Gregersen Echers

Food Chem· January 2025

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Voltage Gated Calcium Channel Dysregulation May Contribute to Neurological Symptoms in Calmodulinopathies.
John W Hussey, Emily DeMarco, Deborah DiSilvestre, Malene Brohus, Ana-Octavia Busuioc, Michael T Overgaard

bioRxiv· December 2024

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Role of Calmodulin in Cardiac Disease: Insights on Genotype and Phenotype.
Peter J Schwartz, Lia Crotti, Mette Nyegaard, Michael Toft Overgaard

Circ Genom Precis Med· October 2024

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Decoding the impact of neighboring amino acids on ESI-MS intensity output through deep learning.
Naim Abdul-Khalek, Reinhard Wimmer, Michael Toft Overgaard, Simon Gregersen Echers

J Proteomics· October 2024

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Calmodulin, sudden death, and the Folbigg case: genes in court.
Peter J Schwartz, Lia Crotti, Mette Nyegaard, Michael Toft Overgaard

Eur Heart J· May 2024

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Allosteric changes in protein stability and dynamics as pathogenic mechanism for calmodulin variants not affecting Ca coordinating residues.
Christina Vallentin Holler, Nina Møller Petersson, Malene Brohus, Miska Aleksanteri Niemelä, Emil Drivsholm Iversen, Michael Toft Overgaard

Cell Calcium· January 2024

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Antioxidant peptides from alternative sources reduce lipid oxidation in 5% fish oil-in-water emulsions (pH 4) and fish oil-enriched mayonnaise.
Elisa Varona, Pedro J García-Moreno, Simon Gregersen Echers, Tobias H Olsen, Paolo Marcatili, Michael T Overgaard

Food Chem· November 2023

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Clinical presentation of calmodulin mutations: the International Calmodulinopathy Registry.
Lia Crotti, Carla Spazzolini, Mette Nyegaard, Michael T Overgaard, Maria-Christina Kotta

Eur Heart J· September 2023

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Calmodulin mutations affecting Gly114 impair binding to the Na1.5 IQ-domain.
Malene Brohus, Ana-Octavia Busuioc, Reinhard Wimmer, Mette Nyegaard, Michael Toft Overgaard

Front Pharmacol· August 2023

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Insight on physicochemical properties governing peptide MS1 response in HPLC-ESI-MS/MS: A deep learning approach.
Naim Abdul-Khalek, Reinhard Wimmer, Michael Toft Overgaard, Simon Gregersen Echers

Comput Struct Biotechnol J· July 2023

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Human calmodulin mutations cause arrhythmia and affect neuronal function in C. elegans.
Helene H Jensen, Magnus T Frantzen, Jonas L Wesseltoft, Ana-Octavia Busuioc, Katrine V Møller, Michael T Overgaard

Hum Mol Genet· June 2023

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Hypothyroidism in hibernating brown bears.
Anne Mette Frøbert, Claus G Nielsen, Malene Brohus, Jonas Kindberg, Ole Fröbert, Michael T Overgaard

Thyroid Res· February 2023

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Differential Changes in Circulating Steroid Hormones in Hibernating Brown Bears: Preliminary Conclusions and Caveats.
Anne Mette Frøbert, Julia N C Toews, Claus G Nielsen, Malene Brohus, Jonas Kindberg, Michael T Overgaard

Physiol Biochem Zool· December 2022

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Circulating insulin-like growth factor system adaptations in hibernating brown bears indicate increased tissue IGF availability.
Anne Mette Frøbert, Malene Brohus, Tinna S Roesen, Jonas Kindberg, Ole Fröbert, Michael T Overgaard

Am J Physiol Endocrinol Metab· September 2022

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Antioxidant peptides derived from potato, seaweed, microbial and spinach proteins: Oxidative stability of 5% fish oil-in-water emulsions.
Betül Yesiltas, Pedro J García-Moreno, Simon Gregersen, Tobias H Olsen, Nykola C Jones, Michael T Overgaard

Food Chem· August 2022

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A gain-of-function mutation in the ITPR1 gating domain causes male infertility in mice.
Bo Sun, Mingke Ni, Shanshan Tian, Wenting Guo, Shitian Cai, Michael T Overgaard

J Cell Physiol· August 2022

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Plasma proteomics data from hibernating and active Scandinavian brown bears.
Anne Mette Frøbert, Simon Gregersen, Malene Brohus, Karen G Welinder, Jonas Kindberg, Michael T Overgaard

Data Brief· April 2022

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A systematic approach for evaluating the role of surface-exposed loops in trypsin-like serine proteases applied to the 170 loop in coagulation factor VIIa.
Anders B Sorensen, Per Jr Greisen, Jesper J Madsen, Jacob Lund, Gorm Andersen, Michael T Overgaard

Sci Rep· March 2022

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Characterization and comparison of recombinant full-length ursine and human sex hormone-binding globulin.
Anne Mette Frøbert, Malene Brohus, Julia N C Toews, Phillip Round, Ole Fröbert, Michael T Overgaard

FEBS Open Bio· February 2022

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Polygenic Risk Score Prediction for Endometriosis.
Kirstine Kloeve-Mogensen, Palle Duun Rohde, Simone Twisttmann, Marianne Nygaard, Kristina Magaard Koldby, Michael Toft Overgaard

Front Reprod Health· December 2021

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Emulsifier peptides derived from seaweed, methanotrophic bacteria, and potato proteins identified by quantitative proteomics and bioinformatics.
Betül Yesiltas, Simon Gregersen, Linea Lægsgaard, Maja L Brinch, Tobias H Olsen, Michael T Overgaard

Food Chem· November 2021

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AnOxPePred: using deep learning for the prediction of antioxidative properties of peptides.
Tobias Hegelund Olsen, Betül Yesiltas, Frederikke Isa Marin, Margarita Pertseva, Pedro J García-Moreno, Michael Toft Overgaard

Sci Rep· December 2020

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