Publications by authors named "Michael Walters"

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Development of potent glutathione transferase Omega-1 inhibitors with applications in inflammation and cancer therapy.
Yiyue Xie, Yuji Nakano, Padmaja Tummala, Aaron J Oakley, Adi Suwandi, Michael A Walters

Eur J Med Chem· December 2025

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Reactivation of Oxidized Soluble Guanylate Cyclase as a Novel Treatment Strategy to Slow Progression of Calcific Aortic Valve Stenosis: Preclinical and Randomized Clinical Trials to Assess Safety and Efficacy.
Bin Zhang, Maurice Enriquez-Sarano, Hartzell V Schaff, Hector I Michelena, Carolyn M Roos, Michael A Walters

Circulation· April 2025

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Reengineering of Circularly Permuted Caspase-2 to Enhance Enzyme Stability and Enable Crystallographic Studies.
Jessica L Fuller, Ke Shi, Steffen Pockes, Barry C Finzel, Karen H Ashe, Michael A Walters

ACS Chem Biol· April 2025

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Early oncological outcomes of delayed radical prostatectomy: A prospective, international, follow-up analysis of the COVIDSurg-Cancer study.
Arjun Nathan, Chuanyu Gao, Alexander Light, Cameron Alexander, Vinson Chan, Michael Walters

BJUI Compass· December 2024

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Understanding the long-term impact of the COVID-19 pandemic on non-muscle-invasive bladder cancer outcomes: 12-Month follow-up data from the international, prospective COVIDSurg Cancer study.
Cameron E Alexander, Arjun Nathan, Alexander Light, Chuanyu Gao, Vinson Chan, Michael Walters

BJUI Compass· November 2024

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Discovery of a CK2α'-Biased ATP-Competitive Inhibitor from a High-Throughput Screen of an Allosteric-Inhibitor-Like Compound Library.
Deepti Mudaliar, Rachel H Mansky, Angel White, Grace Baudhuin, Jon Hawkinson, Michael A Walters

ACS Chem Neurosci· August 2024

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Development of Allosteric Small Molecule APOBEC3B Inhibitors from Screening.
Katherine F M Jones, Özlem Demir, Mackenzie K Wyllie, Michael J Grillo, Clare Morris, Michael A Walters

bioRxiv· April 2024

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Identification of CK2α' selective inhibitors by the screening of an allosteric-kinase-inhibitor-like compound library.
Deepti Mudaliar, Rachel H Mansky, Angel White, Grace Baudhuin, Jon Hawkinson, Michael A Walters

bioRxiv· January 2024

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An electrophilic fragment screening for the development of small molecules targeting caspase-2.
Matthew E Cuellar, Mu Yang, Surendra Karavadhi, Ya-Qin Zhang, Hu Zhu, Michael A Walters

Eur J Med Chem· November 2023

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Targeting caspase-2 interactions with tau in Alzheimer's disease and related dementias.
Steffen Pockes, Michael A Walters, Karen H Ashe

Transl Res· April 2023

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Reference compounds for characterizing cellular injury in high-content cellular morphology assays.
Jayme L Dahlin, Bruce K Hua, Beth E Zucconi, Shawn D Nelson, Shantanu Singh, Michael A Walters

Nat Commun· March 2023

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The impact of altering emission data precision on compression efficiency and accuracy of simulations of the community multiscale air quality model.
Michael S Walters, David C Wong

Geosci Model Dev· February 2023

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Characterization of caspase-2 inhibitors based on specific sites of caspase-2-mediated proteolysis.
Merlin Bresinsky, Jessica M Strasser, Alexander Hubmann, Bernadette Vallaster, William M McCue, Michael A Walters

Arch Pharm (Weinheim)· September 2022

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Threonine Cavities Are Targetable Motifs That Control Alpha-Synuclein Fibril Growth.
Noah Nathan Kochen, Vivek Vasandani, Darren Seaney, Anil K Pandey, Michael A Walters

ACS Chem Neurosci· September 2022

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Caspase-2 Inhibitor Blocks Tau Truncation and Restores Excitatory Neurotransmission in Neurons Modeling FTDP-17 Tauopathy.
Gurpreet Singh, Peng Liu, Katherine R Yao, Jessica M Strasser, Chris Hlynialuk, Michael A Walters

ACS Chem Neurosci· May 2022

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Structure-Based Design and Biological Evaluation of Novel Caspase-2 Inhibitors Based on the Peptide AcVDVAD-CHO and the Caspase-2-Mediated Tau Cleavage Sequence YKPVD314.
Merlin Bresinsky, Jessica M Strasser, Bernadette Vallaster, Peng Liu, William M McCue, Michael A Walters

ACS Pharmacol Transl Sci· January 2022

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The Communication of Hit Quality Using Natural History Visualizations (NHVs).
Kathryn M Nelson, Michael A Walters

SLAS Discov· August 2021

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Remodelin Is a Cryptic Assay Interference Chemotype That Does Not Inhibit NAT10-Dependent Cytidine Acetylation.
Jonathan H Shrimp, Yihang Jing, Supuni Thalalla Gamage, Kathryn M Nelson, Joseph Han, Michael A Walters

ACS Med Chem Lett· June 2021

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Nuisance compounds in cellular assays.
Jayme L Dahlin, Douglas S Auld, Ina Rothenaigner, Steve Haney, Jonathan Z Sexton, Michael A Walters

Cell Chem Biol· March 2021

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The COVID-19 Army Rapid Assessment Tool (CARAT) for Management of COVID-19 in the Deployed Setting.
Michael J Walters, Brandon L Aden, Maurice L Kliewer, Charles L Bruehl, Elizabeth M Mannion

Med J (Ft Sam Houst Tex)· March 2021

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Synthesis of Guaianolide Analogues with a Tunable α-Methylene-γ-lactam Electrophile and Correlating Bioactivity with Thiol Reactivity.
Paul A Jackson, Henry A M Schares, Katherine F M Jones, John C Widen, Daniel P Dempe, Michael A Walters

J Med Chem· December 2020

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The Essential Medicinal Chemistry of Cannabidiol (CBD).
Kathryn M Nelson, Jonathan Bisson, Gurpreet Singh, James G Graham, Shao-Nong Chen, Michael A Walters

J Med Chem· November 2020

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Intraoperative core temperature and infectious complications after colorectal surgery: A registry analysis.
Michael J Walters, Marianne Tanios, Onur Koyuncu, Guangmei Mao, Michael A Valente

J Clin Anesth· August 2020

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Discovery of Acylsulfonohydrazide-Derived Inhibitors of the Lysine Acetyltransferase, KAT6A, as Potent Senescence-Inducing Anti-Cancer Agents.
Daniel L Priebbenow, David J Leaver, Nghi Nguyen, Benjamin Cleary, H Rachel Lagiakos, Michael A Walters

J Med Chem· May 2020

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Development of Benzenesulfonamide Derivatives as Potent Glutathione Transferase Omega-1 Inhibitors.
Yiyue Xie, Padmaja Tummala, Aaron J Oakley, Girdhar Singh Deora, Yuji Nakano, Michael A Walters

J Med Chem· March 2020

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