Publications by authors named "Michelle Machacek"

Claim this Profile
D
Design and synthesis of unprecedented 9- and 10-membered cyclonucleosides with PRMT5 inhibitory activity.
Shuhei Kawamura, Rachel L Palte, Hai-Young Kim, Josep Saurí, Christopher Sondey, Michelle R Machacek

Bioorg Med Chem· July 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Diminishing GSH-Adduct Formation of Tricyclic Diazepine-based Mutant IDH1 Inhibitors.
Chunhui Huang, Christian Fischer, Michelle R Machacek, Stephane Bogen, Tesfaye Biftu

ACS Med Chem Lett· April 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
NMR Data-Driven Docking of HDM2-Inhibitor Complexes.
Xavier Fradera, Michael H Reutershan, Michelle R Machacek, B Wesley Trotter, Mark A McCoy

Chembiochem· March 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of : an Efficient Inhibitor of the HDM2-p53 Protein-Protein Interaction.
Michael H Reutershan, Michelle R Machacek, Michael D Altman, Stephane Bogen, Mingmei Cai

J Med Chem· November 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The Discovery of Two Novel Classes of 5,5-Bicyclic Nucleoside-Derived PRMT5 Inhibitors for the Treatment of Cancer.
Ryan V Quiroz, Michael H Reutershan, Sebastian E Schneider, David Sloman, Brian M Lacey, Michelle R Machacek

J Med Chem· April 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Identification of free fatty acid receptor 2 agonists using virtual screening.
James I Fells, Xi Ai, Adam Weinglass, Wen Feng, Ying Lei, Michelle Machacek

Bioorg Med Chem Lett· November 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Allosteric Modulation of Protein Arginine Methyltransferase 5 (PRMT5).
Rachel L Palte, Sebastian E Schneider, Michael D Altman, Robert P Hayes, Shuhei Kawamura, Michelle R Machacek

ACS Med Chem Lett· September 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Identification of predictive genetic signatures of Cytarabine responsiveness using a 3D acute myeloid leukaemia model.
Haiyan Xu, Eric S Muise, Sarah Javaid, Lan Chen, Razvan Cristescu, Michelle Machacek

J Cell Mol Med· October 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Indole acids as a novel PDE2 inhibitor chemotype that demonstrate pro-cognitive activity in multiple species.
Shawn J Stachel, Melissa S Egbertson, Jenny Wai, Michelle Machacek, Dawn M Toolan

Bioorg Med Chem Lett· April 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
U
Update on lymphocyte specific kinase inhibitors: a patent survey.
Matthew W Martin, Michelle R Machacek

Expert Opin Ther Pat· November 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Predicting the stereochemistry of diphenylphosphino benzoic acid (DPPBA)-based palladium-catalyzed asymmetric allylic alkylation reactions: a working model.
Barry M Trost, Michelle R Machacek, Aaron Aponick

Acc Chem Res· October 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Sequential Ru-Pd catalysis: a two-catalyst one-pot protocol for the synthesis of N- and O-heterocycles.
Barry M Trost, Michelle R Machacek, Brian D Faulk

J Am Chem Soc· May 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Development of aliphatic alcohols as nucleophiles for palladium-catalyzed DYKAT reactions: total synthesis of (+)-hippospongic acid A.
Barry M Trost, Michelle R Machacek, Hong C Tsui

J Am Chem Soc· May 2005

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Ruthenium-catalyzed vinylsilane synthesis and cross-coupling as a selective approach to alkenes: benzyldimethylsilyl as a robust vinylmetal functionality.
Barry M Trost, Michelle R Machacek, Zachary T Ball

Org Lett· May 2003

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
An efficient one-pot enantio- and diastereoselective synthesis of heterocycles.
Barry M Trost, Michelle R Machacek

Angew Chem Int Ed Engl· December 2002

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis