Publications by authors named "Michelle Rossulek"

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Ponsegromab for the Treatment of Cancer Cachexia.
John D Groarke, Jeffrey Crawford, Susie M Collins, Shannon Lubaczewski, Eric J Roeland, Michelle Rossulek

N Engl J Med· December 2024

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The mortality burden of cachexia or weight loss in patients with colorectal or pancreatic cancer: A systematic literature review.
Richard F Dunne, Jeffrey Crawford, Karen E Smoyer, Thomas D McRae, Michelle I Rossulek

J Cachexia Sarcopenia Muscle· October 2024

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Mortality burden of pre-treatment weight loss in patients with non-small-cell lung cancer: A systematic literature review and meta-analysis.
Philip D Bonomi, Jeffrey Crawford, Richard F Dunne, Eric J Roeland, Karen E Smoyer, Michelle I Rossulek

J Cachexia Sarcopenia Muscle· August 2024

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Association between growth differentiation factor-15 and adverse outcomes among patients with heart failure: A systematic literature review.
Ali Javaheri, Mualla Ozcan, Lauren Moubarak, Karen E Smoyer, Michelle I Rossulek

Heliyon· August 2024

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Phase 2 study of the efficacy and safety of ponsegromab in patients with cancer cachexia: PROACC-1 study design.
John D Groarke, Jeffrey Crawford, Susie M Collins, Shannon L Lubaczewski, Danna M Breen, Michelle I Rossulek

J Cachexia Sarcopenia Muscle· June 2024

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A Phase Ib First-In-Patient Study Assessing the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Ponsegromab in Participants with Cancer and Cachexia.
Jeffrey Crawford, Roberto A Calle, Susie M Collins, Yan Weng, Shannon L Lubaczewski, Michelle I Rossulek

Clin Cancer Res· February 2024

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Patient Willingness to Use Digital Health Technologies: A Quantitative and Qualitative Survey in Patients with Cancer Cachexia.
Anil Tarachandani, Fikret Isik Karahanoglu, Andrew Messere, Lisa Tarasenko, Ann-Marie LaRonde-Richard, Michelle Rossulek

Patient Prefer Adherence· April 2023

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Preclinical characterization of an intravenous coronavirus 3CL protease inhibitor for the potential treatment of COVID19.
Britton Boras, Rhys M Jones, Brandon J Anson, Dan Arenson, Lisa Aschenbrenner, Michelle I Rossulek

Nat Commun· October 2021

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Discovery of a Novel Inhibitor of Coronavirus 3CL Protease for the Potential Treatment of COVID-19.
Britton Boras, Rhys M Jones, Brandon J Anson, Dan Arenson, Lisa Aschenbrenner, Michelle I Rossulek

bioRxiv· February 2021

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GDF-15 Neutralization Alleviates Platinum-Based Chemotherapy-Induced Emesis, Anorexia, and Weight Loss in Mice and Nonhuman Primates.
Danna M Breen, Hanna Kim, Donald Bennett, Roberto A Calle, Susie Collins, Michelle Rossulek

Cell Metab· December 2020

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Decreased VMAT2 in the pancreas of humans with type 2 diabetes mellitus measured in vivo by PET imaging.
Gary W Cline, Mika Naganawa, Laigao Chen, Kristin Chidsey, Santos Carvajal-Gonzalez, Michelle Rossulek

Diabetologia· December 2018

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A Long-Acting FGF21 Molecule, PF-05231023, Decreases Body Weight and Improves Lipid Profile in Non-human Primates and Type 2 Diabetic Subjects.
Saswata Talukdar, Yingjiang Zhou, Dongmei Li, Michelle Rossulek, Jennifer Dong

Cell Metab· March 2016

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Pharmacokinetics and pharmacodynamics of PF-05231023, a novel long-acting FGF21 mimetic, in a first-in-human study.
Jennifer Q Dong, Michelle Rossulek, Veena R Somayaji, Daniel Baltrukonis, Yali Liang

Br J Clin Pharmacol· November 2015

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Metabolism, pharmacokinetics, and excretion of a cholesteryl ester transfer protein inhibitor, torcetrapib, in rats, monkeys, and mice: characterization of unusual and novel metabolites by high-resolution liquid chromatography-tandem mass spectrometry and 1H nuclear magnetic resonance.
Chandra Prakash, Weichao Chen, Michelle Rossulek, Kim Johnson, Chenghong Zhang

Drug Metab Dispos· October 2008

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Novel CCR1 antagonists with improved metabolic stability.
Matthew F Brown, Mike Avery, William H Brissette, J H Chang, Kevin Colizza, Michelle I Rossulek

Bioorg Med Chem Lett· May 2004

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