Publications by authors named "MuChun Li"

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Quantitative prediction of active components in turnip using near-infrared spectroscopy (NIRS) and a multimodal feature fusion method.
Zhicen Li, Jinmiao Song, Jiaxin Yang, He Tian, Gaoge Tang, Muchun Li

Spectrochim Acta A Mol Biomol Spectrosc· March 2026

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All Solid State Battery with Soft Carbon-TiSi Multilayer Structure for Optimized LiSi Anodes.
Qian Li, WeiTao He, MuChun Li, JiXian Luo, Wenlin Yan, Liquan Chen

Adv Mater· October 2025

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KIF2C promotes paclitaxel resistance by depolymerizing polyglutamylated microtubules.
Yuan-Shao Pao, Kuan-Ju Liao, Ya-Chia Shiau, Ming-Hong Chao, Mu-Chun Li, Li-Mei Lin, Shu-Yu Lin, Yu-Chun Lin, Lily Hui-Ching Wang

Dev Cell· August 2025

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Structure-Based Design of Potent and Selective MerTK Inhibitors by Modulating the Conformation of αC Helix.
Yi-Hui Peng, Mu-Chun Li, Wan-Ching Yen, Teng-Kuang Yeh, Ching-Cheng Hsueh, You-Liang Lai, Ling Chang

J Med Chem· June 2025

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Identification and Biological Evaluation of a Novel CLK4 Inhibitor Targeting Alternative Splicing in Pancreatic Cancer Using Structure-Based Virtual Screening.
Chun-Lin Yang, Yi-Wen Wu, Huang-Ju Tu, Yun-Hsuan Yeh, Tony Eight Lin, Mu-Chun Li, Shiow-Lin Pan

Adv Sci (Weinh)· May 2025

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Aldehyde dehydrogenases as drug targets for cancer: SAR and structural biology aspects for inhibitor design.
Himanshu Tahiliani, Arunkumar Dhayalan, Mu-Chun Li, Hsing-Pang Hsieh, Mohane Selvaraj Coumar

Bioorg Chem· January 2025

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Discovery of novel TANK-Binding Kinase 1 (TBK1) inhibitor against pancreatic ductal adenocarcinoma.
Wan-Hsi Shih, Han-Li Huang, Wei-Chun HuangFu, Tony Eight Lin, Tzu-Ying Sung, Mu-Chun Li, Guan-Lin Huang, Shiow-Lin Pan

Int J Biol Macromol· December 2024

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Optimization of enzyme-assisted microwave extraction, structural characterization, antioxidant activity and in vitro protective effect against HO-induced damage in HepG2 cells of polysaccharides from roots of Rubus crataegifolius Bunge.
Huiling Chen, Zifan Bai, Shuo Tao, Muchun Li, Liqiao Jian

Int J Biol Macromol· September 2024

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Discovery of Dual MER/AXL Kinase Inhibitors as Bifunctional Small Molecules for Inhibiting Tumor Growth and Enhancing Tumor Immune Microenvironment.
Mu-Chun Li, You-Liang Lai, Po-Hsien Kuo, Julakanti Satyanarayana Reddy, Chih-Ming Chen, Chin-Yu Lin, Ling Chang, Wen-Hsing Lin

J Med Chem· July 2024

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Targeting cancer-associated fibroblast autophagy renders pancreatic cancer eradicable with immunochemotherapy by inhibiting adaptive immune resistance.
Xiaozhen Zhang, Mengyi Lao, Hanshen Yang, Kang Sun, Yunfei Dong, Lihong He, Muchun Li, Xinyuan Liu, Xueli Bai, Tingbo Liang

Autophagy· June 2024

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Targeting leucine-rich repeat serine/threonine-protein kinase 2 sensitizes pancreatic ductal adenocarcinoma to anti-PD-L1 immunotherapy.
Kang Sun, Xiaozhen Zhang, Mengyi Lao, Lihong He, Sicheng Wang, Muchun Li, Xinyuan Liu, Jieru Lin, Tingbo Liang, Xueli Bai

Mol Ther· October 2023

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Targeting MFAP5 in cancer-associated fibroblasts sensitizes pancreatic cancer to PD-L1-based immunochemotherapy via remodeling the matrix.
Yi Duan, Xiaozhen Zhang, Honggang Ying, Jian Xu, Hanshen Yang, Lihong He, Muchun Li, Tingbo Liang, Xueli Bai

Oncogene· June 2023

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Targeting ubiquitin-specific protease 8 sensitizes anti-programmed death-ligand 1 immunotherapy of pancreatic cancer.
Hanshen Yang, Xiaozhen Zhang, Mengyi Lao, Kang Sun, Lihong He, Muchun Li, Tingbo Liang, Xueli Bai

Cell Death Differ· February 2023

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Development of Furanopyrimidine-Based Orally Active Third-Generation EGFR Inhibitors for the Treatment of Non-Small Cell Lung Cancer.
Mu-Chun Li, Mohane Selvaraj Coumar, Shu-Yu Lin, Yih-Shyan Lin, Guan-Lin Huang, Tzu-Wen Lien, Bikashita Kalita, Shiow-Lin Pan

J Med Chem· February 2023

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Gut flora disequilibrium promotes the initiation of liver cancer by modulating tryptophan metabolism and up-regulating SREBP2.
Wen Chen, Liang Wen, Yingying Bao, Zengwei Tang, Jianhui Zhao, Jin Li, Muchun Li, Tingbo Liang

Proc Natl Acad Sci U S A· December 2022

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A critical overview of current progress for COVID-19: development of vaccines, antiviral drugs, and therapeutic antibodies.
Monika Kumari, Ruei-Min Lu, Mu-Chun Li, Jhih-Liang Huang, Fu-Fei Hsu, Kang-Hao Liang, Hsiao-Ling Chiang, Wen-Shan Li

J Biomed Sci· September 2022

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Targeting TNFR2: A Novel Breakthrough in the Treatment of Cancer.
Muchun Li, Xiaozhen Zhang, Xueli Bai, Tingbo Liang

Front Oncol· April 2022

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Quality Assessment of L. Using Quantitative Analysis of Multi-Components by Single Marker and Fingerprint Analysis.
Xueqin Cao, Muchun Li, Liuchun Ma, Miaomiao Wang, Xueling Hou

Molecules· April 2022

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Combination cancer immunotherapy targeting TNFR2 and PD-1/PD-L1 signaling reduces immunosuppressive effects in the microenvironment of pancreatic tumors.
Xiaozhen Zhang, Mengyi Lao, Jian Xu, Yi Duan, Hanshen Yang, Muchun Li, Lihong He, Xueli Bai, Tingbo Liang

J Immunother Cancer· March 2022

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Global profiling of regulatory elements in the histone benzoylation pathway.
Duo Wang, Fuxiang Yan, Ping Wu, Kexue Ge, Muchun Li, Tingting Li

Nat Commun· March 2022

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Design and synthesis of novel orally selective and type II pan-TRK inhibitors to overcome mutations by property-driven optimization.
Mu-Chun Li, Wen-Hsing Lin, Pei-Chen Wang, Yu-Chieh Su, Pei-Yi Chen, Ling Chang

Eur J Med Chem· November 2021

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CK1δ stimulates ubiquitination-dependent proteasomal degradation of ATF4 to promote chemoresistance in gastric Cancer.
Lifeng Feng, Muchun Li, Xinyang Hu, Yiling Li, Liyuan Zhu

Clin Transl Med· October 2021

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Sirt1 deacetylates and stabilizes p62 to promote hepato-carcinogenesis.
Lifeng Feng, Miaoqin Chen, Yiling Li, Muchun Li, Shiman Hu, Liyuan Zhu, Linghui Tan

Cell Death Dis· April 2021

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Mimicking H3 Substrate Arginine in the Design of G9a Lysine Methyltransferase Inhibitors for Cancer Therapy: A Computational Study for Structure-Based Drug Design.
M Ramya Chandar Charles, Mu-Chun Li, Hsing-Pang Hsieh, Mohane Selvaraj Coumar

ACS Omega· March 2021

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Design of drug-like hepsin inhibitors against prostate cancer and kidney stones.
Vincent Blay, Mu-Chun Li, Sunita P Ho, Mashall L Stoller, Hsing-Pang Hsieh

Acta Pharm Sin B· July 2020

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