Publications by authors named "Nan Laird"

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X chromosome associations with chronic obstructive pulmonary disease and related phenotypes: an X chromosome-wide association study.
Lystra P Hayden, Brian D Hobbs, Robert Busch, Michael H Cho, Ming Liu, Nan M Laird

Respir Res· February 2023

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Region-based analysis of rare genomic variants in whole-genome sequencing datasets reveal two novel Alzheimer's disease-associated genes: DTNB and DLG2.
Dmitry Prokopenko, Sanghun Lee, Julian Hecker, Kristina Mullin, Sarah Morgan, Nan Laird

Mol Psychiatry· April 2022

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Genome-wide association analysis of COVID-19 mortality risk in SARS-CoV-2 genomes identifies mutation in the SARS-CoV-2 spike protein that colocalizes with P.1 of the Brazilian strain.
Georg Hahn, Chloe M Wu, Sanghun Lee, Sharon M Lutz, Surender Khurana, Nan M Laird

Genet Epidemiol· October 2021

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A unifying framework for rare variant association testing in family-based designs, including higher criticism approaches, SKATs, and burden tests.
Julian Hecker, F William Townes, Priyadarshini Kachroo, Cecelia Laurie, Jessica Lasky-Su, Nan M Laird

Bioinformatics· April 2021

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Statistical considerations for the analysis of massively parallel reporter assays data.
Dandi Qiao, Corwin M Zigler, Michael H Cho, Edwin K Silverman, Xiaobo Zhou, Nan H Laird

Genet Epidemiol· October 2020

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Identification of Novel Alzheimer's Disease Loci Using Sex-Specific Family-Based Association Analysis of Whole-Genome Sequence Data.
Dmitry Prokopenko, Julian Hecker, Rory Kirchner, Brad A Chapman, Oliver Hoffman, Nan Laird

Sci Rep· March 2020

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Exome sequencing in schizophrenia-affected parent-offspring trios reveals risk conferred by protein-coding de novo mutations.
Daniel P Howrigan, Samuel A Rose, Kaitlin E Samocha, Menachem Fromer, Felecia Cerrato, Nan Laird

Nat Neurosci· February 2020

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A comparison of popular TDT-generalizations for family-based association analysis.
Julian Hecker, Nan Laird, Christoph Lange

Genet Epidemiol· April 2019

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Family-based tests for associating haplotypes with general phenotype data: Improving the FBAT-haplotype algorithm.
Julian Hecker, Xin Xu, F William Townes, Heide Loehlein Fier, Chris Corcoran, Nan Laird

Genet Epidemiol· February 2018

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Gene-based segregation method for identifying rare variants in family-based sequencing studies.
Dandi Qiao, Christoph Lange, Nan M Laird, Sungho Won, Craig P Hersh

Genet Epidemiol· May 2017

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Genome-Wide Association Study of the Genetic Determinants of Emphysema Distribution.
Adel Boueiz, Sharon M Lutz, Michael H Cho, Craig P Hersh, Russell P Bowler, Nan M Laird

Am J Respir Crit Care Med· March 2017

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Sex-Based Genetic Association Study Identifies CELSR1 as a Possible Chronic Obstructive Pulmonary Disease Risk Locus among Women.
Megan Hardin, Michael H Cho, Sunita Sharma, Kimberly Glass, Peter J Castaldi, Nan Laird

Am J Respir Cell Mol Biol· March 2017

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Statistical Methods in the Journal - An Update.
Yasunori Sato, Masahiko Gosho, Kengo Nagashima, Sho Takahashi, James H Ware, Nan M Laird

N Engl J Med· March 2017

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Exome Array Analysis Identifies a Common Variant in IL27 Associated with Chronic Obstructive Pulmonary Disease.
Brian D Hobbs, Margaret M Parker, Han Chen, Taotao Lao, Megan Hardin, Nan M Laird

Am J Respir Crit Care Med· July 2016

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Integrating Multiple Correlated Phenotypes for Genetic Association Analysis by Maximizing Heritability.
Jin J Zhou, Michael H Cho, Christoph Lange, Sharon Lutz, Edwin K Silverman, Nan M Laird

Hum Hered· March 2016

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A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Sharon M Lutz, Michael H Cho, Kendra Young, Craig P Hersh, Peter J Castaldi, Nan M Laird

BMC Genet· December 2015

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Socioeconomic disadvantage and neural development from infancy through early childhood.
Galen Chin-Lun Hung, Jill Hahn, Bibi Alamiri, Stephen L Buka, Jill M Goldstein, Nan Laird

Int J Epidemiol· December 2015

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Meta-analysis in clinical trials revisited.
Rebecca DerSimonian, Nan Laird

Contemp Clin Trials· November 2015

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A Genome-Wide Association Study of Emphysema and Airway Quantitative Imaging Phenotypes.
Michael H Cho, Peter J Castaldi, Craig P Hersh, Brian D Hobbs, R Graham Barr, Nan M Laird

Am J Respir Crit Care Med· September 2015

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A novel method for detecting association between DNA methylation and diseases using spatial information.
Wai-Ki Yip, Heide Fier, Dawn L DeMeo, Martin Aryee, Nan Laird

Genet Epidemiol· December 2014

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A comparative analysis of family-based and population-based association tests using whole genome sequence data.
Jin J Zhou, Wai-Ki Yip, Michael H Cho, Dandi Qiao, Merry-Lynn N McDonald, Nan M Laird

BMC Proc· December 2014

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Genome-wide association identifies regulatory Loci associated with distinct local histogram emphysema patterns.
Peter J Castaldi, Michael H Cho, Raúl San José Estépar, Merry-Lynn N McDonald, Nan Laird

Am J Respir Crit Care Med· August 2014

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Analyzing networks of phenotypes in complex diseases: methodology and applications in COPD.
Jen-hwa Chu, Craig P Hersh, Peter J Castaldi, Michael H Cho, Benjamin A Raby, Nan Laird

BMC Syst Biol· June 2014

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Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis.
Michael H Cho, Merry-Lynn N McDonald, Xiaobo Zhou, Manuel Mattheisen, Peter J Castaldi, Nan M Laird

Lancet Respir Med· March 2014

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Distinct quantitative computed tomography emphysema patterns are associated with physiology and function in smokers.
Peter J Castaldi, Raúl San José Estépar, Carlos S Mendoza, Craig P Hersh, Nan Laird

Am J Respir Crit Care Med· November 2013

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