Publications by authors named "Nicholas Bleeker"

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A novel SERCA inhibitor demonstrates synergy with classic SERCA inhibitors and targets multidrug-resistant AML.
Nicholas P Bleeker, Razvan L Cornea, David D Thomas, Chengguo Xing

Mol Pharm· November 2013

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Ethyl 2-amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate (CXL017): a novel scaffold that resensitizes multidrug resistant leukemia cells to chemotherapy.
Sonia G Das, David L Hermanson, Nicholas Bleeker, Xazmin Lowman, Yunfang Li

ACS Chem Biol· February 2013

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Synthesis and evaluation of the anti-proliferative and NF-κB activities of a library of simplified tylophorine analogs.
Micah J Niphakis, Bryant C Gay, Kwon Ho Hong, Nicholas P Bleeker, Gunda I Georg

Bioorg Med Chem· October 2012

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Structure-activity relationship (SAR) study of ethyl 2-amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate (CXL017) and the potential of the lead against multidrug resistance in cancer treatment.
Gopalakrishnan Aridoss, Bo Zhou, David L Hermanson, Nicholas P Bleeker, Chengguo Xing

J Med Chem· June 2012

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Structure-activity relationship and molecular mechanisms of ethyl 2-amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate (CXL017) and its analogues.
Sonia G Das, Balasubramanian Srinivasan, David L Hermanson, Nicholas P Bleeker, Jignesh M Doshi

J Med Chem· August 2011

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