Publications by authors named "Nicholas Duggan"

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Levels of orientation bias differ across digital content categories: Implications for visual perception.
Nicholas Duggan, Peter Gerhardstein

Perception· April 2023

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Correction to "Discovery of Fevipiprant (NVP-QAW039), a Potent and Selective DP Receptor Antagonist for Treatment of Asthma".
David A Sandham, Lucy Barker, Lyndon Brown, Zarin Brown, David Budd, Nicholas Duggan

ACS Med Chem Lett· September 2017

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Discovery of Fevipiprant (NVP-QAW039), a Potent and Selective DP Receptor Antagonist for Treatment of Asthma.
David A Sandham, Lucy Barker, Lyndon Brown, Zarin Brown, David Budd, Nicholas Duggan

ACS Med Chem Lett· May 2017

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Novel ROCK inhibitors for the treatment of pulmonary arterial hypertension.
Duncan Shaw, Greg Hollingworth, Nicolas Soldermann, Elizabeth Sprague, Walter Schuler, Nicholas Duggan

Bioorg Med Chem Lett· October 2014

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A translational preclinical model of interstitial pulmonary fibrosis and pulmonary hypertension: mechanistic pathways driving disease pathophysiology.
Elizabeth R Jarman, Valerie S Khambata, Li Yun Ye, Kenneth Cheung, Matthew Thomas, Nicholas Duggan

Physiol Rep· September 2014

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Sex-dependent influence of endogenous estrogen in pulmonary hypertension.
Kirsty M Mair, Audrey F Wright, Nicholas Duggan, David J Rowlands, Martin J Hussey

Am J Respir Crit Care Med· August 2014

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An inhibitor of NADPH oxidase-4 attenuates established pulmonary fibrosis in a rodent disease model.
Elizabeth R Jarman, Valerie S Khambata, Claire Cope, Peter Jones, Jan Roger, Nicholas Duggan

Am J Respir Cell Mol Biol· January 2014

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Discovery and characterization of NVP-QAV680, a potent and selective CRTh2 receptor antagonist suitable for clinical testing in allergic diseases.
David A Sandham, Nicola Arnold, Heinrich Aschauer, Kamlesh Bala, Lucy Barker, Nicholas Duggan

Bioorg Med Chem· November 2013

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Treatment with anti-gremlin 1 antibody ameliorates chronic hypoxia/SU5416-induced pulmonary arterial hypertension in mice.
Loredana Ciuclan, Kellyann Sheppard, Liqun Dong, Daniel Sutton, Nicholas Duggan

Am J Pathol· November 2013

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Imatinib attenuates hypoxia-induced pulmonary arterial hypertension pathology via reduction in 5-hydroxytryptamine through inhibition of tryptophan hydroxylase 1 expression.
Loredana Ciuclan, Martin J Hussey, Victoria Burton, Robert Good, Nicholas Duggan

Am J Respir Crit Care Med· January 2013

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A novel murine model of severe pulmonary arterial hypertension.
Loredana Ciuclan, Olivier Bonneau, Martin Hussey, Nicholas Duggan, Alan M Holmes

Am J Respir Crit Care Med· November 2011

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Essential role of phosphoinositide 3-kinase gamma in eosinophil chemotaxis within acute pulmonary inflammation.
Matthew Thomas, Matthew J Edwards, Elzbieta Sawicka, Nicholas Duggan, Emilio Hirsch

Immunology· March 2009

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Activin-like kinase 5 (ALK5) mediates abnormal proliferation of vascular smooth muscle cells from patients with familial pulmonary arterial hypertension and is involved in the progression of experimental pulmonary arterial hypertension induced by monocrotaline.
Matthew Thomas, Cerys Docx, Alan M Holmes, Sarah Beach, Nicholas Duggan

Am J Pathol· February 2009

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