Publications by authors named "Nicolas Soldermann"

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Direct and selective pharmacological disruption of the YAP-TEAD interface by IAG933 inhibits Hippo-dependent and RAS-MAPK-altered cancers.
Emilie A Chapeau, Laurent Sansregret, Giorgio G Galli, Patrick Chène, Markus Wartmann, Nicolas Soldermann

Nat Cancer· July 2024

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Author Correction: Direct and selective pharmacological disruption of the YAP-TEAD interface by IAG933 inhibits Hippo-dependent and RAS-MAPK-altered cancers.
Emilie A Chapeau, Laurent Sansregret, Giorgio G Galli, Patrick Chène, Markus Wartmann, Nicolas Soldermann

Nat Cancer· July 2024

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Optimization of a Class of Dihydrobenzofurane Analogs toward Orally Efficacious YAP-TEAD Protein-Protein Interaction Inhibitors.
Holger Sellner, Emilie Chapeau, Pascal Furet, Markus Voegtle, Bahaa Salem, Nicolas Soldermann

ChemMedChem· June 2023

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The First Class of Small Molecules Potently Disrupting the YAP-TEAD Interaction by Direct Competition.
Pascal Furet, Vincent Bordas, Mickaël Le Douget, Bahaa Salem, Yannick Mesrouze, Nicolas Soldermann

ChemMedChem· October 2022

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Effective "activated PI3Kδ syndrome"-targeted therapy with the PI3Kδ inhibitor leniolisib.
V Koneti Rao, Sharon Webster, Virgil A S H Dalm, Anna Šedivá, P Martin van Hagen, Nicolas Soldermann

Blood· November 2017

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Discovery of CDZ173 (Leniolisib), Representing a Structurally Novel Class of PI3K Delta-Selective Inhibitors.
Klemens Hoegenauer, Nicolas Soldermann, Frédéric Zécri, Ross S Strang, Nadege Graveleau

ACS Med Chem Lett· September 2017

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Discovery of novel pyrrolidineoxy-substituted heteroaromatics as potent and selective PI3K delta inhibitors with improved physicochemical properties.
Klemens Hoegenauer, Nicolas Soldermann, Christina Hebach, Gregory J Hollingworth, Ian Lewis

Bioorg Med Chem Lett· December 2016

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Discovery and Pharmacological Characterization of Novel Quinazoline-Based PI3K Delta-Selective Inhibitors.
Klemens Hoegenauer, Nicolas Soldermann, Frédéric Stauffer, Pascal Furet, Nadege Graveleau

ACS Med Chem Lett· August 2016

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Novel ROCK inhibitors for the treatment of pulmonary arterial hypertension.
Duncan Shaw, Greg Hollingworth, Nicolas Soldermann, Elizabeth Sprague, Walter Schuler

Bioorg Med Chem Lett· October 2014

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6-Amino quinazolinedione sulfonamides as orally active competitive AMPA receptor antagonists.
David Orain, Silvio Ofner, Manuel Koller, David A Carcache, Wolfgang Froestl, Nicolas Soldermann

Bioorg Med Chem Lett· January 2012

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2,6-Naphthyridines as potent and selective inhibitors of the novel protein kinase C isozymes.
Maurice J van Eis, Jean-Pierre Evenou, Philipp Floersheim, Christoph Gaul, Sandra W Cowan-Jacob, Nicolas Soldermann

Bioorg Med Chem Lett· December 2011

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3,5-diarylazoles as novel and selective inhibitors of protein kinase D.
Gabriel G Gamber, Erik Meredith, Qingming Zhu, Wanlin Yan, Chang Rao, Nicolas Soldermann

Bioorg Med Chem Lett· March 2011

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Identification of potent and selective amidobipyridyl inhibitors of protein kinase D.
Erik L Meredith, Kimberly Beattie, Robin Burgis, Michael Capparelli, Joseph Chapo, Nicolas Soldermann

J Med Chem· August 2010

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Pharmacophore mapping in the laulimalide series: total synthesis of a vinylogue for a late-stage metathesis diversification strategy.
Paul A Wender, Michael K Hilinski, Philip R Skaanderup, Nicolas G Soldermann, Susan L Mooberry

Org Lett· August 2006

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Total synthesis and biological evaluation of 11-desmethyllaulimalide, a highly potent simplified laulimalide analogue.
Paul A Wender, Michael K Hilinski, Nicolas Soldermann, Susan L Mooberry

Org Lett· March 2006

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Origins of boat or chair preferences in the Ireland-Claisen rearrangements of cyclohexenyl esters: a theoretical study.
Mahmood M Khaledy, Mohammad Y S Kalani, Kelli S Khuong, K N Houk, Viktorya Aviyente, Nicolas Soldermann

J Org Chem· January 2003

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