Publications by authors named "Nicholas Liau"

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Decreased lipidated ApoE-receptor interactions confer protection against pathogenicity of ApoE and its lipid cargoes in lysosomes.
Jing L Guo, Dylan Braun, Gabriel A Fitzgerald, Yun-Ting Hsieh, Lionel Rougé, Nicholas P D Liau

Cell· January 2025

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Author Correction: CIS is a potent checkpoint in NK cell-mediated tumor immunity.
Rebecca B Delconte, Tatiana B Kolesnik, Laura F Dagley, Jai Rautela, Wei Shi, Nicholas P D Liau

Nat Immunol· February 2024

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Author Correction: CD98hc is a target for brain delivery of biotherapeutics.
Kylie S Chew, Robert C Wells, Arash Moshkforoush, Darren Chan, Kendra J Lechtenberg, Nicholas P D Liau

Nat Commun· September 2023

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CD98hc is a target for brain delivery of biotherapeutics.
Kylie S Chew, Robert C Wells, Arash Moshkforoush, Darren Chan, Kendra J Lechtenberg, Nicholas P D Liau

Nat Commun· August 2023

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Filling a nick in NIK: Extending the half-life of a NIK inhibitor through structure-based drug design.
James J Crawford, Jianwen Feng, Hans D Brightbill, Adam R Johnson, Matthew Wright, Nicholas Liau

Bioorg Med Chem Lett· June 2023

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Structure guided studies of the interaction between PTP1B and JAK.
Rhiannon Morris, Narelle Keating, Cyrus Tan, Hao Chen, Artem Laktyushin, Nicholas P D Liau

Commun Biol· June 2023

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Synthetic Multivalent Disulfide-Constrained Peptide Agonists Potentiate Wnt1/β-Catenin Signaling via LRP6 Coreceptor Clustering.
Avinash K Thakur, Stephen E Miller, Nicholas P D Liau, Sunhee Hwang, Simon Hansen

ACS Chem Biol· April 2023

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Structural basis for SHOC2 modulation of RAS signalling.
Nicholas P D Liau, Matthew C Johnson, Saeed Izadi, Luca Gerosa, Michal Hammel

Nature· September 2022

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CRAF dimerization with ARAF regulates KRAS-driven tumor growth.
Avinashnarayan Venkatanarayan, Jason Liang, Ivana Yen, Frances Shanahan, Benjamin Haley, Nicholas P D Liau

Cell Rep· February 2022

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ARAF mutations confer resistance to the RAF inhibitor belvarafenib in melanoma.
Ivana Yen, Frances Shanahan, Jeeyun Lee, Yong Sang Hong, Sang Joon Shin, Nicholas P D Liau

Nature· June 2021

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Dimerization Induced by C-Terminal 14-3-3 Binding Is Sufficient for BRAF Kinase Activation.
Nicholas P D Liau, Avinashnarayan Venkatanarayan, John G Quinn, Wilson Phung, Shiva Malek

Biochemistry· October 2020

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Negative regulation of RAF kinase activity by ATP is overcome by 14-3-3-induced dimerization.
Nicholas P D Liau, Timothy J Wendorff, John G Quinn, Micah Steffek, Wilson Phung

Nat Struct Mol Biol· February 2020

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Enzymatic Characterization of Wild-Type and Mutant Janus Kinase 1.
Nicholas P D Liau, Artem Laktyushin, Rhiannon Morris, Jarrod J Sandow, Nicos A Nicola

Cancers (Basel)· November 2019

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Expression and Purification of JAK1 and SOCS1 for Structural and Biochemical Studies.
Nicholas P D Liau, Jeffrey J Babon

Methods Mol Biol· January 2019

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Accumulation of JAK activation loop phosphorylation is linked to type I JAK inhibitor withdrawal syndrome in myelofibrosis.
Denis Tvorogov, Daniel Thomas, Nicholas P D Liau, Mara Dottore, Emma F Barry

Sci Adv· November 2018

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The molecular basis of JAK/STAT inhibition by SOCS1.
Nicholas P D Liau, Artem Laktyushin, Isabelle S Lucet, James M Murphy, Shenggen Yao

Nat Commun· April 2018

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Purification of SOCS (Suppressor of Cytokine Signaling) SH2 Domains for Structural and Functional Studies.
Nicholas P D Liau, Artem Laktyushin, Jeffrey J Babon

Methods Mol Biol· February 2018

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CIS is a potent checkpoint in NK cell-mediated tumor immunity.
Rebecca B Delconte, Tatiana B Kolesnik, Laura F Dagley, Jai Rautela, Wei Shi, Nicholas P D Liau

Nat Immunol· July 2016

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JAK1 Takes a FERM Hold of Type II Cytokine Receptors.
Jeffrey J Babon, Nicholas P D Liau, Nadia J Kershaw

Structure· June 2016

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Mechanistic insights into activation and SOCS3-mediated inhibition of myeloproliferative neoplasm-associated JAK2 mutants from biochemical and structural analyses.
Leila N Varghese, Daniela Ungureanu, Nicholas P D Liau, Samuel N Young, Artem Laktyushin

Biochem J· March 2014

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SOCS3 binds specific receptor-JAK complexes to control cytokine signaling by direct kinase inhibition.
Nadia J Kershaw, James M Murphy, Nicholas P D Liau, Leila N Varghese, Artem Laktyushin

Nat Struct Mol Biol· April 2013

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F-18 FDG PET/CT detection of mediastinal malignancy in a patient with dermatomyositis.
Nicholas Liau, Colin Ooi, Catherine Reid, Ian D Kirkwood, Dylan Bartholomeusz

Clin Nucl Med· April 2007

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