Publications by authors named "Nicholas Navin"

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CoCo-ST detects global and local biological structures in spatial transcriptomics datasets.
Muhammad Aminu, Bo Zhu, Natalie Vokes, Hong Chen, Lingzhi Hong, Nicholas Navin

Nat Cell Biol· November 2025

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Coalescing single-cell genomes and transcriptomes to decode breast cancer progression.
Kaile Wang, Rui Ye, Shanshan Bai, Zhenna Xiao, Lei Yang, Nicholas E Navin

Cell· October 2025

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Defining breast epithelial cell types in the single-cell era.
G Kenneth Gray, Eric G Carlson, Tatyana Lev, Bailey Marshall, Austin D Reed, Nicholas Navin

Dev Cell· September 2025

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Radiotherapy promotes cuproptosis and synergizes with cuproptosis inducers to overcome tumor radioresistance.
Guang Lei, Mingchuang Sun, Jun Cheng, Rui Ye, Zhengze Lu, Nicholas Navin

Cancer Cell· June 2025

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A spatial atlas of chemoradiation therapy in pancreatic cancer identifies cellular and microenvironmental determinants of persister populations.
Vincent Bernard, Li-Ting Ku, Tianyu Wang, Ariana Acevedo-Diaz, Kimal I Rajapakshe, Nicholas E Navin

bioRxiv· June 2025

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Longitudinal Profiling of Circulating Tumor DNA Reveals the Evolutionary Dynamics of Metastatic Prostate Cancer during Serial Therapy.
Yuehui Zhao, Naveen Ramesh, Ping Xu, Emi Sei, Min Hu, Nicholas E Navin

Cancer Res· May 2025

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The impact of breast radiotherapy on the tumor genome and immune ecosystem.
Aislyn Schalck, Tuan Tran, Jianzhuo Li, Emi Sei, Shanshan Bai, Nicholas E Navin

Cell Rep· May 2025

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The dynamic immune behavior of primary and metastatic ovarian carcinoma.
Elaine Stur, Fuduan Peng, Pang-Ning Teng, Emine Bayraktar, Min Hu, Nicholas E Navin

NPJ Precis Oncol· April 2025

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Immune landscape of isocitrate dehydrogenase-stratified primary and recurrent human gliomas.
Pravesh Gupta, Minghao Dang, Shivangi Oberai, Simona Migliozzi, Rakesh Trivedi, Nicholas E Navin

Neuro Oncol· December 2024

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Normal breast tissues harbour rare populations of aneuploid epithelial cells.
Yiyun Lin, Junke Wang, Kaile Wang, Shanshan Bai, Aatish Thennavan, Nicholas Navin

Nature· December 2024

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Single cell genome and epigenome co-profiling reveals hardwiring and plasticity in breast cancer.
Kaile Wang, Yun Yan, Heba Elgamal, Jianzhuo Li, Chenling Tang, Nicholas Navin

bioRxiv· September 2024

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Single-nucleotide variant calling in single-cell sequencing data with Monopogen.
Jinzhuang Dou, Yukun Tan, Kian Hong Kock, Jun Wang, Xuesen Cheng, Nicholas Navin

Nat Biotechnol· May 2024

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A spatially resolved single-cell genomic atlas of the adult human breast.
Tapsi Kumar, Kevin Nee, Runmin Wei, Siyuan He, Quy H Nguyen, Nicholas Navin

Nature· August 2023

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Archival single-cell genomics reveals persistent subclones during DCIS progression.
Kaile Wang, Tapsi Kumar, Junke Wang, Darlan Conterno Minussi, Emi Sei, Nicholas E Navin

Cell· August 2023

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Anaplastic transformation in thyroid cancer revealed by single-cell transcriptomics.
Lina Lu, Jennifer Rui Wang, Ying C Henderson, Shanshan Bai, Jie Yang, Nicholas Navin

J Clin Invest· June 2023

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Dimeric p53 Mutant Elicits Unique Tumor-Suppressive Activities through an Altered Metabolic Program.
Jovanka Gencel-Augusto, Xiaoping Su, Yuan Qi, Elizabeth M Whitley, Vinod Pant, Nicholas E Navin

Cancer Discov· May 2023

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Dissociation protocols used for sarcoma tissues bias the transcriptome observed in single-cell and single-nucleus RNA sequencing.
Danh D Truong, Salah-Eddine Lamhamedi-Cherradi, Robert W Porter, Sandhya Krishnan, Jyothishmathi Swaminathan, Nicholas E Navin

BMC Cancer· May 2023

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A spatially resolved single cell genomic atlas of the adult human breast.
Tapsi Kumar, Kevin Nee, Runmin Wei, Siyuan He, Quy H Nguyen, Nicholas Navin

bioRxiv· April 2023

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Author Correction: Learning to distinguish progressive and non-progressive ductal carcinoma in situ.
Anna K Casasent, Mathilde M Almekinders, Charlotta Mulder, Proteeti Bhattacharjee, Deborah Collyar, Nicholas E Navin

Nat Rev Cancer· February 2023

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Targeting T cell checkpoints 41BB and LAG3 and myeloid cell CXCR1/CXCR2 results in antitumor immunity and durable response in pancreatic cancer.
Pat Gulhati, Aislyn Schalck, Shan Jiang, Xiaoying Shang, Chang-Jiun Wu, Nicholas E Navin

Nat Cancer· January 2023

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Reconstructing mutational lineages in breast cancer by multi-patient-targeted single-cell DNA sequencing.
Jake Leighton, Min Hu, Emi Sei, Funda Meric-Bernstam, Nicholas E Navin

Cell Genom· January 2023

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Learning to distinguish progressive and non-progressive ductal carcinoma in situ.
Anna K Casasent, Mathilde M Almekinders, Charlotta Mulder, Proteeti Bhattacharjee, Deborah Collyar, Nicholas E Navin

Nat Rev Cancer· December 2022

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EGFR is a master switch between immunosuppressive and immunoactive tumor microenvironment in inflammatory breast cancer.
Xiaoping Wang, Takashi Semba, Ganiraju C Manyam, Jing Wang, Shan Shao, Nicholas Navin

Sci Adv· December 2022

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MEDICC2: whole-genome doubling aware copy-number phylogenies for cancer evolution.
Tom L Kaufmann, Marina Petkovic, Thomas B K Watkins, Emma C Colliver, Sofya Laskina, Nicholas Navin

Genome Biol· November 2022

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Spatial intra-tumor heterogeneity is associated with survival of lung adenocarcinoma patients.
Hua-Jun Wu, Daniel Temko, Zoltan Maliga, Andre L Moreira, Emi Sei, Nicholas Navin

Cell Genom· August 2022

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