Publications by authors named "Nigel Botting"

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Anthocyanins and their physiologically relevant metabolites alter the expression of IL-6 and VCAM-1 in CD40L and oxidized LDL challenged vascular endothelial cells.
Hiren P Amin, Charles Czank, Saki Raheem, Qingzhi Zhang, Nigel P Botting

Mol Nutr Food Res· June 2015

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Methods for isolating, identifying, and quantifying anthocyanin metabolites in clinical samples.
Rachel M de Ferrars, Charles Czank, Shikha Saha, Paul W Needs, Qingzhi Zhang, Nigel P Botting

Anal Chem· October 2014

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Quantification of soy isoflavones and their conjugative metabolites in plasma and urine: an automated and validated UHPLC-MS/MS method for use in large-scale studies.
Sebastian T Soukup, Nawaf Al-Maharik, Nigel Botting, Sabine E Kulling

Anal Bioanal Chem· September 2014

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Synthesis and biological evaluation of nitric oxide-donating analogues of sulindac for prostate cancer treatment.
Andrew Nortcliffe, Alexander G Ekstrom, James R Black, James A Ross, Fouad K Habib, Nigel P Botting

Bioorg Med Chem· January 2014

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Novel amino acids: synthesis of furoxan and sydnonimine containing amino acids and peptides as potential nitric oxide releasing motifs.
Andrew Nortcliffe, Nigel P Botting, David O'Hagan

Org Biomol Chem· July 2013

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Development and characterization of glutamyl-protected N-hydroxyguanidines as reno-active nitric oxide donor drugs with therapeutic potential in acute renal failure.
Qingzhi Zhang, Philip Milliken, Agnieszka Kulczynska, Alex M Z Slawin, Adele Gordon, Nigel P Botting

J Med Chem· July 2013

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Human metabolism and elimination of the anthocyanin, cyanidin-3-glucoside: a (13)C-tracer study.
Charles Czank, Aedín Cassidy, Qingzhi Zhang, Douglas J Morrison, Tom Preston, Nigel P Botting

Am J Clin Nutr· May 2013

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A new class of NO-donor pro-drugs triggered by γ-glutamyl transpeptidase with potential for reno-selective vasodilatation.
Qingzhi Zhang, Agnieszka Kulczynska, David J Webb, Ian L Megson, Nigel P Botting

Chem Commun (Camb)· February 2013

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A gram scale synthesis of a multi-13C-labelled anthocyanin, [6,8,10,3',5'-13C5]cyanidin-3-glucoside, for use in oral tracer studies in humans.
Qingzhi Zhang, Nigel P Botting, Colin Kay

Chem Commun (Camb)· October 2011

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The metabolism and analysis of isoflavones and other dietary polyphenols in foods and biological systems.
Stephen Barnes, Jeevan Prasain, Tracy D'Alessandro, Ali Arabshahi, Nigel Botting

Food Funct· May 2011

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Flavonoid conjugates interact with organic anion transporters (OATs) and attenuate cytotoxicity of adefovir mediated by organic anion transporter 1 (OAT1/SLC22A6).
Chi Chun Wong, Nigel P Botting, Caroline Orfila, Nawaf Al-Maharik, Gary Williamson

Biochem Pharmacol· April 2011

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Bioavailability of Sulforaphane from two broccoli sprout beverages: results of a short-term, cross-over clinical trial in Qidong, China.
Patricia A Egner, Jian Guo Chen, Jin Bing Wang, Yan Wu, Yan Sun, Nigel P Botting

Cancer Prev Res (Phila)· March 2011

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Disposition of soy isoflavones in normal human breast tissue.
Selin Bolca, Mireia Urpi-Sarda, Phillip Blondeel, Nathalie Roche, Lynn Vanhaecke, Nigel Botting

Am J Clin Nutr· April 2010

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First synthesis of [1,3,5-(13)C3]gallic acid.
Laura J Marshall, Karl M Cable, Nigel P Botting

Org Biomol Chem· February 2009

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Orally administered isoflavones are present as glucuronides in the human prostate.
Laurent Guy, Nicolas Védrine, Mireia Urpi-Sarda, Angel Gil-Izquierdo, Nawaf Al-Maharik, Nigel P Botting

Nutr Cancer· November 2008

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1-(5-Chloro-2,4-dihydroxy-phen-yl)-2-(4-ethoxy-phen-yl)ethanone.
Nigel P Botting, Alexandra M Z Slawin, Qingzhi Zhang

Acta Crystallogr Sect E Struct Rep Online· September 2008

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Structural and kinetic characterization of quinolinate phosphoribosyltransferase (hQPRTase) from homo sapiens.
Huanting Liu, Kerry Woznica, Gemma Catton, Amanda Crawford, Nigel Botting

J Mol Biol· October 2007

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Anti-inflammatory effects of isoflavones are dependent on flow and human endothelial cell PPARgamma.
Balu K Chacko, Robert T Chandler, Tracy L D'Alessandro, Ameya Mundhekar, Nicholas K H Khoo, Nigel Botting

J Nutr· February 2007

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Synthesis of multiply 13C-labeled furofuran lignans using 13C-labeled cinnamyl alcohols as building blocks.
Kati Haajanen, Nigel P Botting

Steroids· March 2006

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Metabolism of phytoestrogen conjugates.
Tracy L D'Alessandro, Brenda J Boersma-Maland, T Greg Peterson, Jeff Sfakianos, Jeevan K Prasain, Nigel P Botting

Methods Enzymol· February 2006

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Analysis of glucosinolates, isothiocyanates, and amine degradation products in vegetable extracts and blood plasma by LC-MS/MS.
Lijiang Song, John J Morrison, Nigel P Botting, Paul J Thornalley

Anal Biochem· December 2005

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Quantification of lignans in food using isotope dilution gas chromatography/mass spectrometry.
José L Peñalvo, Kati M Haajanen, Nigel Botting, Herman Adlercreutz

J Agric Food Chem· November 2005

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Determination of lignans in human plasma by liquid chromatography with coulometric electrode array detection.
José L Peñalvo, Tarja Nurmi, Kati Haajanen, Nawaf Al-Maharik, Nigel Botting

Anal Biochem· September 2004

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Phytoestrogen concentrations in serum and spot urine as biomarkers for dietary phytoestrogen intake and their relation to breast cancer risk in European prospective investigation of cancer and nutrition-norfolk.
Philip B Grace, James I Taylor, Yen-Ling Low, Robert N Luben, Angela A Mulligan, Nigel P Botting

Cancer Epidemiol Biomarkers Prev· May 2004

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Sulfation of genistein alters its antioxidant properties and its effect on platelet aggregation and monocyte and endothelial function.
Gerald Rimbach, Peter D Weinberg, Sonia de Pascual-Teresa, Maria Garcia Alonso, Ben A Ewins, Nigel Botting

Biochim Biophys Acta· February 2004

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