Publications by authors named "Nikolay Ninov"

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Developmental beta-cell death orchestrates the islet's inflammatory milieu by regulating immune system crosstalk.
Mohammad Nadeem Akhtar, Alisa Hnatiuk, Luis Delgadillo-Silva, Shirin Geravandi, Katrin Sameith, Nikolay Ninov

EMBO J· February 2025

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Transcriptomic heterogeneity of non-beta islet cells is associated with type 2 diabetes development in mouse models.
Pascal Gottmann, Thilo Speckmann, Mandy Stadion, Prateek Chawla, Judith Saurenbach, Nikolay Ninov

Diabetologia· January 2025

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Optogenetic β cell interrogation in vivo reveals a functional hierarchy directing the Ca response to glucose supported by vitamin B6.
Luis Fernando Delgadillo-Silva, Emirhan Tasöz, Sumeet Pal Singh, Prateek Chawla, Eleni Georgiadou, Nikolay Ninov

Sci Adv· June 2024

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A missense mutation in the proprotein convertase gene furinb causes hepatic cystogenesis during liver development in zebrafish.
Jillian L Ellis, Kimberley J Evason, Changwen Zhang, Makenzie N Fourman, Jiandong Liu, Nikolay Ninov

Hepatol Commun· November 2022

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Wnt4 is heterogeneously activated in maturing β-cells to control calcium signaling, metabolism and function.
Keiichi Katsumoto, Siham Yennek, Chunguang Chen, Luis Fernando Delgadillo Silva, Sofia Traikov, Nikolay Ninov

Nat Commun· October 2022

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A single-cell atlas of de novo β-cell regeneration reveals the contribution of hybrid β/δ-cells to diabetes recovery in zebrafish.
Sumeet Pal Singh, Prateek Chawla, Alisa Hnatiuk, Margrit Kamel, Luis Delgadillo Silva, Nikolay Ninov

Development· January 2022

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Simultaneous Calcium Imaging and Glucose Stimulation in Living Zebrafish to Investigate In Vivo β-Cell Function.
Luis Fernando Delgadillo-Silva, Mohammad Nadeem Akhtar, Emirhan Taşöz, Nikolay Ninov

J Vis Exp· September 2021

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Sexually dimorphic roles for the type 2 diabetes-associated C2cd4b gene in murine glucose homeostasis.
S Neda Mousavy Gharavy, Bryn M Owen, Steven J Millership, Pauline Chabosseau, Grazia Pizza, Nikolay Ninov

Diabetologia· April 2021

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Multicolor Labeling and Tracing of Pancreatic Beta-Cell Proliferation in Zebrafish.
Sumeet Pal Singh, Nikolay Ninov

Methods Mol Biol· March 2021

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Single-cell transcriptome analysis reveals thyrocyte diversity in the zebrafish thyroid gland.
Pierre Gillotay, Meghna Shankar, Benoit Haerlingen, Eski Sema Elif, Macarena Pozo-Morales, Nikolay Ninov

EMBO Rep· December 2020

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Comment on Satin et al. "Take Me To Your Leader": An Electrophysiological Appraisal of the Role of Hub Cells in Pancreatic Islets. Diabetes 2020;69:830-836.
Guy A Rutter, Nikolay Ninov, Victoria Salem, David J Hodson

Diabetes· September 2020

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Leader β-cells coordinate Ca dynamics across pancreatic islets in vivo.
Victoria Salem, Luis Delgadillo Silva, Kinga Suba, Eleni Georgiadou, S Neda Mousavy Gharavy, Nikolay Ninov

Nat Metab· June 2019

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The triumvirate of beta-cell regeneration: solutions and bottlenecks to curing diabetes.
Sumeet P Singh, Nikolay Ninov

Int J Dev Biol· April 2019

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Nano-Sampling and Reporter Tools to Study Metabolic Regulation in Zebrafish.
Thomas Dickmeis, Yi Feng, Maria Caterina Mione, Nikolay Ninov, Massimo Santoro

Front Cell Dev Biol· February 2019

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Modelling pancreatic β-cell inflammation in zebrafish identifies the natural product wedelolactone for human islet protection.
Luis Fernando Delgadillo-Silva, Anastasia Tsakmaki, Nadeem Akhtar, Zara J Franklin, Judith Konantz, Nikolay Ninov

Dis Model Mech· January 2019

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Machine learning based classification of cells into chronological stages using single-cell transcriptomics.
Sumeet Pal Singh, Sharan Janjuha, Samata Chaudhuri, Susanne Reinhardt, Annekathrin Kränkel, Nikolay Ninov

Sci Rep· November 2018

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Analysis of Beta-cell Function Using Single-cell Resolution Calcium Imaging in Zebrafish Islets.
Sharan Janjuha, Sumeet Pal Singh, Nikolay Ninov

J Vis Exp· July 2018

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Wnt/β-catenin signaling controls intrahepatic biliary network formation in zebrafish by regulating notch activity.
Juhoon So, Mehwish Khaliq, Kimberley Evason, Nikolay Ninov, Benjamin L Martin

Hepatology· June 2018

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Simultaneous lineage tracing and cell-type identification using CRISPR-Cas9-induced genetic scars.
Bastiaan Spanjaard, Bo Hu, Nina Mitic, Pedro Olivares-Chauvet, Sharan Janjuha, Nikolay Ninov

Nat Biotechnol· June 2018

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Age-related islet inflammation marks the proliferative decline of pancreatic beta-cells in zebrafish.
Sharan Janjuha, Sumeet Pal Singh, Anastasia Tsakmaki, S Neda Mousavy Gharavy, Priyanka Murawala, Nikolay Ninov

Elife· April 2018

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Catching new targets in metabolic disease with a zebrafish.
Margrit Kamel, Nikolay Ninov

Curr Opin Pharmacol· December 2017

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Bone morphogenetic protein signaling governs biliary-driven liver regeneration in zebrafish through tbx2b and id2a.
Tae-Young Choi, Mehwish Khaliq, Shinya Tsurusaki, Nikolay Ninov, Didier Y R Stainier

Hepatology· November 2017

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Different developmental histories of beta-cells generate functional and proliferative heterogeneity during islet growth.
Sumeet Pal Singh, Sharan Janjuha, Theresa Hartmann, Özge Kayisoglu, Judith Konantz, Nikolay Ninov

Nat Commun· September 2017

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Distinct Levels of Reactive Oxygen Species Coordinate Metabolic Activity with Beta-cell Mass Plasticity.
Ezzaldin Ahmed Alfar, Dilyana Kirova, Judith Konantz, Sarah Birke, Jörg Mansfeld, Nikolay Ninov

Sci Rep· June 2017

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Current advances in tissue repair and regeneration: the future is bright.
Nikolay Ninov, Maximina H Yun

Regeneration (Oxf)· April 2015

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