Publications by authors named "Nilesh Samani"

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Genomic and transcriptomic analyses of aortic stenosis enhance therapeutic target discovery and disease prediction.
Aeron M Small, Ta-Yu Yang, Shinsuke Itoh, Sébastien Thériault, Line Dufresne, Nilesh J Samani

Nat Genet· December 2025

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Higher dietary n - 3 PUFA and fiber intake are associated with longer leukocyte telomere length: Evidence from a substitution model analysis in the UK Biobank.
Vasiliki Bountziouka, Christopher P Nelson, Veryan Codd, Nilesh J Samani

Nutr Res· October 2025

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Polygenic prediction of body mass index and obesity through the life course and across ancestries.
Roelof A J Smit, Kaitlin H Wade, Qin Hui, Joshua D Arias, Xianyong Yin, Nilesh J Samani

Nat Med· September 2025

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Evaluation of current indirect methods for measuring LDL-cholesterol.
Sophia Drobnik, Hubert Scharnagl, Nilesh J Samani, Peter S Braund, Christopher P Nelson

Clin Chem Lab Med· May 2025

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Genome-wide association study meta-analysis provides insights into the etiology of heart failure and its subtypes.
Albert Henry, Xiaodong Mo, Chris Finan, Mark D Chaffin, Doug Speed, Nilesh J Samani

Nat Genet· April 2025

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Leucocyte telomere length and conduction system ageing.
Stefan van Duijvenboden, Christopher P Nelson, Zahra Raisi-Estabragh, Julia Ramirez, Michele Orini, Nilesh J Samani

Heart· March 2025

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Activation of Neutrophil Extracellular Trap Formation in Patients with Heart Failure and a Preserved Ejection Fraction.
Bart J VAN Essen, Jasper Tromp, Andreas B Gevaert, Tristan V De Jong, Wouter Ouwerkerk, Nilesh J Samani

J Card Fail· March 2025

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Distinct Genetic Risk Profile in Aortic Stenosis Compared With Coronary Artery Disease.
Teresa Trenkwalder, Carlo Maj, Baravan Al-Kassou, Radoslaw Debiec, Stefanie A Doppler, Nilesh J Samani

JAMA Cardiol· February 2025

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Heart failure with improved versus persistently reduced left ventricular ejection fraction: A comparison of the BIOSTAT-CHF (European) study with the ASIAN-HF registry.
Thong Huy Cao, Wan Ting Tay, Donald J L Jones, John G F Cleland, Jasper Tromp, Nilesh J Samani

Eur J Heart Fail· December 2024

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Micronutrient intake and telomere length: findings from the UK Biobank.
Marianna Spinou, Androniki Naska, Christopher P Nelson, Veryan Codd, Nilesh J Samani

Eur J Nutr· December 2024

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Genome-wide association analysis provides insights into the molecular etiology of dilated cardiomyopathy.
Sean L Zheng, Albert Henry, Douglas Cannie, Michael Lee, David Miller, Nilesh J Samani

Nat Genet· December 2024

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Discovery of myosin light chain kinase gene variant in a patient with tetralogy of Fallot suffering aortic dissection: Implications for pathogenesis and the role of family and population screening.
Radoslaw Debiec, Armia Ebeid, Stephen Hamby, Odeta Anciunaite, Anne Illsley, Nilesh J Samani

Int J Cardiol Congenit Heart Dis· December 2024

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Correction: Micronutrient intake and telomere length: findings from the UK Biobank.
Marianna Spinou, Androniki Naska, Christopher P Nelson, Veryan Codd, Nilesh J Samani

Eur J Nutr· December 2024

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The transcriptional profile of iron deficiency in patients with heart failure: Heme-sparing and reduced immune processes.
Niels Grote Beverborg, Ridha I S Alnuwaysir, George Markousis-Mavrogenis, Martijn F Hoes, Haye H van der Wal, Nilesh J Samani

Eur J Heart Fail· December 2024

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Polygenic risk score adds to a clinical risk score in the prediction of cardiovascular disease in a clinical setting.
Nilesh J Samani, Emma Beeston, Chris Greengrass, Fernando Riveros-McKay, Radoslaw Debiec

Eur Heart J· September 2024

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Genetic architecture of telomere length in 462,666 UK Biobank whole-genome sequences.
Oliver S Burren, Ryan S Dhindsa, Sri V V Deevi, Sean Wen, Abhishek Nag, Nilesh J Samani

Nat Genet· September 2024

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Genetic influence on vascular smooth muscle cell apoptosis.
David G McVey, Catherine Andreadi, Peng Gong, Paulina J Stanczyk, Charles U Solomon, Nilesh J Samani

Cell Death Dis· June 2024

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Four-week inhibition of the renin-angiotensin system in spontaneously hypertensive rats results in persistently lower blood pressure with reduced kidney renin and changes in expression of relevant gene networks.
Sean G Byars, Priscilla R Prestes, Varaporn Suphapimol, Fumihiko Takeuchi, Nathan De Vries, Nilesh Samani

Cardiovasc Res· May 2024

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Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits.
Jacob M Keaton, Zoha Kamali, Tian Xie, Ahmad Vaez, Ariel Williams, Nilesh J Samani

Nat Genet· May 2024

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Biomarker and transcriptomics profiles of serum selenium concentrations in patients with heart failure are associated with immunoregulatory processes.
Ali A Al-Mubarak, George Markousis Mavrogenis, Xuanxuan Guo, Marco De Bruyn, Mintu Nath, Nilesh J Samani

Redox Biol· April 2024

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Differential biomarker expression in heart failure patients with and without mitral regurgitation: Insights from BIOSTAT-CHF.
Marianna Adamo, Matteo Pagnesi, Mattia Di Pasquale, Alice Ravera, Kenneth Dickstein, Nilesh J Samani

Int J Cardiol· March 2024

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Genetic imputation of kidney transcriptome, proteome and multi-omics illuminates new blood pressure and hypertension targets.
Xiaoguang Xu, Chachrit Khunsriraksakul, James M Eales, Sebastien Rubin, David Scannali, Nilesh J Samani

Nat Commun· March 2024

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Coronary artery disease and outcomes following transcatheter aortic valve implantation.
Sameer Kurmani, Bhavik Modi, Aditya Mukherjee, David Adlam, Amerjeet Banning, Nilesh J Samani

Open Heart· March 2024

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Multiomics Analysis Provides Novel Pathways Related to Progression of Heart Failure.
Wouter Ouwerkerk, Joao P Belo Pereira, Troy Maasland, Johanna E Emmens, Sylwia M Figarska, Nilesh J Samani

J Am Coll Cardiol· November 2023

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Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci.
Lisa de las Fuentes, Karen L Schwander, Michael R Brown, Amy R Bentley, Thomas W Winkler, Nilesh J Samani

Front Genet· November 2023

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