Publications by authors named "Nullin Divecha"

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Cellular and functional insights into FIH-mediated hydroxylation of TRPA1.
Tao Guo, Dianne Marquez Lopez, Siyuan Wang, Liudi Yao, Xi Li, Nullin Divecha

J Biol Chem· November 2025

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Enhancing Gene Delivery in NB-4 Cells: Overcoming Transduction and Selection Challenges.
Stefano Leto, Sonakshi Gehlot, Bhavwanti Sheth, Stefano Ratti, Lucia Manzoli, Nullin Divecha

Cells· November 2024

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Mechanisms of SARS-CoV-2 Inactivation Using UVC Laser Radiation.
George Devitt, Peter B Johnson, Niall Hanrahan, Simon I R Lane, Magdalena C Vidale, Nullin Divecha

ACS Photonics· January 2024

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A luminescence-based reporter to study tau secretion reveals overlapping mechanisms for the release of healthy and pathological tau.
Dianne Marquez Lopez, Connor J Maltby, Hannah Warming, Nullin Divecha, Mariana Vargas-Caballero

Front Neurosci· June 2023

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Nuclear Phosphoinositides as Key Determinants of Nuclear Functions.
Magdalena C Vidalle, Bhavwanti Sheth, Antonietta Fazio, Maria Vittoria Marvi, Stefano Leto, Nullin Divecha

Biomolecules· June 2023

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PIP4K2B is mechanoresponsive and controls heterochromatin-driven nuclear softening through UHRF1.
Alessandro Poli, Fabrizio A Pennacchio, Andrea Ghisleni, Mariagrazia di Gennaro, Margaux Lecacheur, Nullin Divecha

Nat Commun· March 2023

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Identification and optimization of a novel series of selective PIP5K inhibitors.
David M Andrews, Sharon Cartic, Sabina Cosulich, Nullin Divecha, Paul Faulder

Bioorg Med Chem· January 2022

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Proteomic characterization of GSK3β knockout shows altered cell adhesion and metabolic pathway utilisation in colorectal cancer cells.
Emily Bowler-Barnett, Francisco D Martinez-Garcia, Matthew Sherwood, Ahood Aleidan, Steve John, Nullin Divecha

PLoS One· December 2021

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PIP4Ks impact on PI3K, FOXP3, and UHRF1 signaling and modulate human regulatory T cell proliferation and immunosuppressive activity.
Alessandro Poli, Shidqiyyah Abdul-Hamid, Antonio Enrico Zaurito, Francesca Campagnoli, Valeria Bevilacqua, Nullin Divecha

Proc Natl Acad Sci U S A· August 2021

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"Modulating Phosphoinositide Profiles as a Roadmap for Treatment in Acute Myeloid Leukemia".
Stefano Ratti, Camilla Evangelisti, Sara Mongiorgi, Alessia De Stefano, Antonietta Fazio, Nullin Divecha

Front Oncol· May 2021

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Deep proteomic analysis of Dnmt1 mutant/hypomorphic colorectal cancer cells reveals dysregulation of epithelial-mesenchymal transition and subcellular re-localization of Beta-Catenin.
Emily H Bowler, Alex Smith-Vidal, Alex Lester, Joseph Bell, Zhenghe Wang, Nullin Divecha

Epigenetics· April 2021

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Exploring the controversial role of PI3K signalling in CD4 regulatory T (T-Reg) cells.
Alessandro Poli, Roberta Fiume, Sara Mongiorgi, Antonio Zaurito, Bhavwanti Sheth, Nullin Divecha

Adv Biol Regul· May 2020

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Phosphatidylinositol 5 Phosphate (PI5P): From Behind the Scenes to the Front (Nuclear) Stage.
Alessandro Poli, Antonio Enrico Zaurito, Shidqiyyah Abdul-Hamid, Roberta Fiume, Irene Faenza, Nullin Divecha

Int J Mol Sci· April 2019

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Proteomic Analysis of Azacitidine-Induced Degradation Profiles Identifies Multiple Chromatin and Epigenetic Regulators Including Uhrf1 and Dnmt1 as Sensitive to Azacitidine.
Emily H Bowler, Joseph Bell, Nullin Divecha, Paul Skipp, Rob M Ewing

J Proteome Res· March 2019

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Phosphatidylinositol-5-Phosphate 4-Kinases Regulate Cellular Lipid Metabolism By Facilitating Autophagy.
Mark R Lundquist, Marcus D Goncalves, Ryan M Loughran, Elite Possik, Tarika Vijayaraghavan, Nullin Divecha

Mol Cell· May 2018

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PIP4K2B: Coupling GTP Sensing to PtdIns5P Levels to Regulate Tumorigenesis.
Roberta Fiume, David R Jones, Nullin Divecha

Trends Biochem Sci· June 2016

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Phosphoinositides in the nucleus and myogenic differentiation: how a nuclear turtle with a PHD builds muscle.
Nullin Divecha

Biochem Soc Trans· February 2016

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PIP4K and the role of nuclear phosphoinositides in tumour suppression.
Roberta Fiume, Yvette Stijf-Bultsma, Zahid H Shah, Willem Jan Keune, David R Jones, Nullin Divecha

Biochim Biophys Acta· June 2015

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The basal transcription complex component TAF3 transduces changes in nuclear phosphoinositides into transcriptional output.
Yvette Stijf-Bultsma, Lilly Sommer, Maria Tauber, Mai Baalbaki, Panagiota Giardoglou, Nullin Divecha

Mol Cell· May 2015

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A targeted knockdown screen of genes coding for phosphoinositide modulators identifies PIP4K2A as required for acute myeloid leukemia cell proliferation and survival.
Julian G Jude, Gary J Spencer, Xu Huang, Tim D D Somerville, David R Jones, Nullin Divecha

Oncogene· March 2015

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The hexosamine biosynthesis pathway and O-GlcNAcylation maintain insulin-stimulated PI3K-PKB phosphorylation and tumour cell growth after short-term glucose deprivation.
David R Jones, Willem-Jan Keune, Karen E Anderson, Len R Stephens, Phillip T Hawkins, Nullin Divecha

FEBS J· August 2014

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Accessibility of different histone H3-binding domains of UHRF1 is allosterically regulated by phosphatidylinositol 5-phosphate.
Kathy A Gelato, Maria Tauber, Michelle S Ong, Stefan Winter, Kyoko Hiragami-Hamada, Nullin Divecha

Mol Cell· June 2014

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Nuclear phosphoinositides and their impact on nuclear functions.
Zahid H Shah, David R Jones, Lilly Sommer, Rebecca Foulger, Yvette Bultsma, Nullin Divecha

FEBS J· December 2013

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Low PIP4K2B expression in human breast tumors correlates with reduced patient survival: A role for PIP4K2B in the regulation of E-cadherin expression.
Willem-Jan Keune, Andrew H Sims, David R Jones, Yvette Bultsma, James T Lynch, Nullin Divecha

Cancer Res· December 2013

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Collaboration of AMPK and PKC to induce phosphorylation of Ser413 on PIP5K1B resulting in decreased kinase activity and reduced PtdIns(4,5)P2 synthesis in response to oxidative stress and energy restriction.
Iman van den Bout, David R Jones, Zahid H Shah, Jonathan R Halstead, Willem-Jan Keune, Nullin Divecha

Biochem J· November 2013

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