Publications by authors named "Olga Nemirovskiy"

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Modulation of cellular S1P levels with a novel, potent and specific inhibitor of sphingosine kinase-1.
Mark E Schnute, Matthew D McReynolds, Tom Kasten, Matthew Yates, Gina Jerome, Olga Nemirovskiy

Biochem J· May 2012

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High-throughput screening assay for sphingosine kinase inhibitors in whole blood using RapidFire® mass spectrometry.
Maureen K Highkin, Matthew P Yates, Olga V Nemirovskiy, William A Lamarr, Grace E Munie

J Biomol Screen· February 2011

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Cartilage degradation biomarkers predict efficacy of a novel, highly selective matrix metalloproteinase 13 inhibitor in a dog model of osteoarthritis: confirmation by multivariate analysis that modulation of type II collagen and aggrecan degradation peptides parallels pathologic changes.
Steven Settle, Lillian Vickery, Olga Nemirovskiy, Tom Vidmar, Alison Bendele

Arthritis Rheum· October 2010

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Design and validation of an immunoaffinity LC-MS/MS assay for the quantification of a collagen type II neoepitope peptide in human urine: application as a biomarker of osteoarthritis.
Olga Nemirovskiy, Wenlin Wendy Li, Gabriella Szekely-Klepser

Methods Mol Biol· August 2010

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Pharmacokinetic/pharmacodynamic (PK/PD) differentiation of native and PEGylated recombinant human growth hormone (rhGH and PEG-rhGH) in the rat model of osteoarthritis.
Olga Nemirovskiy, Yi J Zheng, David Tung, Brian Korniski, Steve Settle

Xenobiotica· August 2010

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A novel autotaxin inhibitor reduces lysophosphatidic acid levels in plasma and the site of inflammation.
James Gierse, Atli Thorarensen, Konstantine Beltey, Erica Bradshaw-Pierce, Luz Cortes-Burgos, Olga Nemirovskiy

J Pharmacol Exp Ther· July 2010

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Biochemical, cellular, and anti-inflammatory properties of a potent, selective, orally bioavailable benzamide inhibitor of Rho kinase activity.
Lakshman E Rajagopalan, Michael S Davies, Larry E Kahn, Christine M Kornmeier, Hideaki Shimada, Olga V Nemirovskiy

J Pharmacol Exp Ther· June 2010

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Distinction of microsomal prostaglandin E synthase-1 (mPGES-1) inhibition from cyclooxygenase-2 inhibition in cells using a novel, selective mPGES-1 inhibitor.
Gabriel Mbalaviele, Adele M Pauley, Alexander F Shaffer, Ben S Zweifel, Sumathy Mathialagan, Olga V Nemirovskiy

Biochem Pharmacol· May 2010

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Discovery of (pyridin-4-yl)-2H-tetrazole as a novel scaffold to identify highly selective matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis.
Mark E Schnute, Patrick M O'Brien, Joe Nahra, Mark Morris, W Howard Roark, Olga Nemirovskiy

Bioorg Med Chem Lett· January 2010

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ADAM-8 isolated from human osteoarthritic chondrocytes cleaves fibronectin at Ala(271).
Marc D Zack, Anne-Marie Malfait, Adam P Skepner, Matthew P Yates, David W Griggs, Olga V Nemirovskiy

Arthritis Rheum· September 2009

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Plasma 3-nitrotyrosine is a biomarker in animal models of arthritis: Pharmacological dissection of iNOS' role in disease.
Olga V Nemirovskiy, Melissa R Radabaugh, Poonam Aggarwal, Christie L Funckes-Shippy, Stephen J Mnich

Nitric Oxide· May 2009

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LC-MS/MS mediated absolute quantification and comparison of bile salt export pump and breast cancer resistance protein in livers and hepatocytes across species.
Na Li, Joe Palandra, Olga V Nemirovskiy, Yurong Lai

Anal Chem· March 2009

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Immunoaffinity liquid chromatography-tandem mass spectrometry detection of nitrotyrosine in biological fluids: development of a clinically translatable biomarker.
Melissa R Radabaugh, Olga V Nemirovskiy, Thomas P Misko, Poonam Aggarwal, W Rodney Mathews

Anal Biochem· September 2008

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Absolute quantification of multidrug resistance-associated protein 2 (MRP2/ABCC2) using liquid chromatography tandem mass spectrometry.
Na Li, Olga V Nemirovskiy, Yiqun Zhang, Haodan Yuan, Jianming Mo

Anal Biochem· September 2008

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Clinical validation of an immunoaffinity LC-MS/MS assay for the quantification of a collagen type II neoepitope peptide: A biomarker of matrix metalloproteinase activity and osteoarthritis in human urine.
Wenlin Wendy Li, Olga Nemirovskiy, Scott Fountain, W Rodney Mathews, Gabriella Szekely-Klepser

Anal Biochem· October 2007

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Identification of an ADAMTS-4 cleavage motif using phage display leads to the development of fluorogenic peptide substrates and reveals matrilin-3 as a novel substrate.
Robert Hills, Richard Mazzarella, Kam Fok, Min Liu, Olga Nemirovskiy

J Biol Chem· April 2007

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Unexpected fragmentation of beta-substituted meso-tetraphenylporphyrins induced by high-energy collisional activation.
M Rosario M Domingues, M Graça O S Marques, Cristina M A Alonso, M Graça P M S Neves, J A S Cavaleiro, Olga V Nemirovskiy

J Am Soc Mass Spectrom· December 2002

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