Publications by authors named "Orla Sheils"

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Multi-omic analysis of PBMCs in sepsis reveals widespread cytotoxic dysfunction and an increased population of expressing naïve CD4+ T cells.
Joshua Flynn, Anne Marie Baird, Eamon Breen, Michael Carty, Ciara S McNevin, Orla Sheils

Front Immunol· November 2025

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Prevalence of Mismatch Repair Deficiency in Primary Prostate Cancer in a Large Prospective Cohort.
Ciara S McNevin, Anna Keogh, Mutaz Mohammed Nur, Brianán McGovern, Julie McFadden, Orla Sheils

Clin Cancer Res· May 2025

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Deep feature batch correction using ComBat for machine learning applications in computational pathology.
Pierre Murchan, Pilib Ó Broin, Anne-Marie Baird, Orla Sheils, Stephen P Finn

J Pathol Inform· December 2024

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Surrogate Biomarker Prediction from Whole-Slide Images for Evaluating Overall Survival in Lung Adenocarcinoma.
Pierre Murchan, Anne-Marie Baird, Pilib Ó Broin, Orla Sheils, Stephen P Finn

Diagnostics (Basel)· February 2024

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Implementing a physiotherapy led cancer exercise programme in a National Cancer Centre: the FIXCAS study.
Kate Devenney, Niamh Murphy, Ronan Ryan, Clíona Grant, M John Kennedy, Orla Sheils

Physiotherapy· September 2023

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Developing a health promoting university in Trinity College Dublin-overview and outline process evaluation.
Catherine D Darker, Martina Mullin, Louise Doyle, Michelle Tanner, David McGrath, Orla Sheils

Health Promot Int· August 2023

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The Lung Microbiome in COPD and Lung Cancer: Exploring the Potential of Metal-Based Drugs.
Megan O'Shaughnessy, Orla Sheils, Anne-Marie Baird

Int J Mol Sci· August 2023

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ExPeCT: a randomised trial examining the impact of exercise on quality of life in men with metastatic prostate cancer.
Gráinne Sheill, Lauren Brady, Brian Hayes, Anne-Marie Baird, Emer Guinan, Orla Sheils

Support Care Cancer· April 2023

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Electroconvulsive Stimulation in Rats Induces Alterations in the Hippocampal miRNome: Translational Implications for Depression.
Karen M Ryan, Paul Smyth, Gordon Blackshields, Laura Kranaster, Alexander Sartorius, Orla Sheils

Mol Neurobiol· March 2023

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Correlation of integrated ERG/PTEN assessment with biochemical recurrence in prostate cancer.
Lauren Brady, Jessica Carlsson, Anne-Marie Baird, Orla Casey, Tatjana Vlajnic, Orla Sheils

Cancer Treat Res Commun· March 2022

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The induction of a mesenchymal phenotype by platelet cloaking of cancer cells is a universal phenomenon.
Cathy D Spillane, Niamh M Cooke, Mark P Ward, Dermot Kenny, Gordon Blackshields, Orla Sheils

Transl Oncol· December 2021

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hsa_circ_0001275 Is One of a Number of circRNAs Dysregulated in Enzalutamide Resistant Prostate Cancer and Confers Enzalutamide Resistance In Vitro.
Marvin C J Lim, Anne-Marie Baird, John Greene, Ciara McNevin, Karine Ronan, Orla Sheils

Cancers (Basel)· December 2021

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Pathogenic Variants as Biomarkers for Risk in Prostate Cancer.
Ciara S McNevin, Karen Cadoo, Anne-Marie Baird, Pierre Murchan, Orla Sheils

Cancers (Basel)· November 2021

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Circulating Tumour Cell Numbers Correlate with Platelet Count and Circulating Lymphocyte Subsets in Men with Advanced Prostate Cancer: Data from the ExPeCT Clinical Trial (CTRIAL-IE 15-21).
Brian Hayes, Lauren Brady, Gráinne Sheill, Anne-Marie Baird, Emer Guinan, Orla Sheils

Cancers (Basel)· September 2021

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Deep Learning of Histopathological Features for the Prediction of Tumour Molecular Genetics.
Pierre Murchan, Cathal Ó'Brien, Shane O'Connell, Ciara S McNevin, Anne-Marie Baird, Orla Sheils

Diagnostics (Basel)· August 2021

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The Role of Human Papilloma Virus in Dictating Outcomes in Head and Neck Squamous Cell Carcinoma.
Shane Brennan, Anne-Marie Baird, Esther O'Regan, Orla Sheils

Front Mol Biosci· June 2021

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Platelet cloaking of circulating tumour cells in patients with metastatic prostate cancer: Results from ExPeCT, a randomised controlled trial.
Lauren Brady, Brian Hayes, Gráinne Sheill, Anne-Marie Baird, Emer Guinan, Orla Sheils

PLoS One· February 2021

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The Role of Cancer Stem Cells in Drug Resistance in Gastroesophageal Junction Adenocarcinoma.
Kate Dinneen, Anne-Marie Baird, Ciara Ryan, Orla Sheils

Front Mol Biosci· February 2021

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Differential CircRNA Expression Signatures May Serve as Potential Novel Biomarkers in Prostate Cancer.
John Greene, Anne-Marie Baird, Marvin Lim, Joshua Flynn, Ciara McNevin, Orla Sheils

Front Cell Dev Biol· February 2021

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Epigenetic Modifier UHRF1 May Be a Potential Target in Malignant Pleural Mesothelioma.
Anne-Marie Baird, Stephen P Finn, Steven G Gray, Orla Sheils

J Thorac Oncol· January 2021

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The feasibility of implementing an exercise programme for deconditioned cancer survivors in a national cancer centre: FIXCAS Study.
Kate Devenney, Niamh Murphy, Ronan Ryan, Clíona Grant, John Kennedy, Orla Sheils

HRB Open Res· December 2020

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Prostate cancer-derived holoclones: a novel and effective model for evaluating cancer stemness.
Louise Flynn, Martin P Barr, Anne-Marie Baird, Paul Smyth, Orla M Casey, Orla Sheils

Sci Rep· July 2020

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Anal cancer in people living with HIV: A case series.
Corinna Sadlier, Almida Lynam, Colm Kerr, Orla Sheils, Colm Bergin

Int J STD AIDS· January 2020

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Suppression of Natural Killer cell NKG2D and CD226 anti-tumour cascades by platelet cloaked cancer cells: Implications for the metastatic cascade.
Christopher D Cluxton, Cathy Spillane, Sharon A O'Toole, Orla Sheils, Clair M Gardiner

PLoS One· December 2019

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Potentially important miRNAs in enteropathy-associated T-cell lymphoma pathogenesis: A pilot study.
Lindsey Clarke, Raju Sr Adduri, Paul Smyth, Fiona Quinn, Michael Jeffers, Orla Sheils

Leuk Res Rep· October 2018

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