Publications by authors named "Ottavio Vitolo"

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"When Will All of This End?": A 65-Year-Old Man With Amyotrophic Lateral Sclerosis and Psychiatric Distress.
Ethan G Lester, Ottavio V Vitolo, Alice Flaherty, Yvan Beaussant, Margaret Cramer

J Clin Psychiatry· December 2023

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Resilient together-ALS: leveraging the NDD transdiagnostic framework to develop an early dyadic intervention for people with amyotrophic lateral sclerosis and their informal care-partners.
Christina L Rush, Ethan G Lester, Heena Manglani, Emily Woodworth, Ottavio Vitolo

Amyotroph Lateral Scler Frontotemporal Degener· June 2023

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REL-1017 (Esmethadone) as Adjunctive Treatment in Patients With Major Depressive Disorder: A Phase 2a Randomized Double-Blind Trial.
Maurizio Fava, Stephen Stahl, Luca Pani, Sara De Martin, Marco Pappagallo, Ottavio V Vitolo

Am J Psychiatry· February 2022

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When real life conditions do not follow textbook diagnosis: A diagnostic challenge from a neuropsychiatric clinic.
Mahdi Razafsha, Karen A Buch, Ottavio V Vitolo, Zeina N Chemali

Int J Psychiatry Med· November 2021

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The N-methyl-D-aspartate receptor antagonist d-methadone acutely improves depressive-like behavior in the forced swim test performance of rats.
Taleen Hanania, Paolo Manfredi, Charles Inturrisi, Ottavio V Vitolo

Exp Clin Psychopharmacol· April 2020

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N-Methyl-D-aspartate receptor antagonist d-methadone produces rapid, mTORC1-dependent antidepressant effects.
Manoela V Fogaça, Kenichi Fukumoto, Tina Franklin, Rong-Jian Liu, Catharine H Duman, Ottavio V Vitolo

Neuropsychopharmacology· December 2019

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Characterization of the Safety and Pharmacokinetic Profile of D-Methadone, a Novel N-Methyl-D-Aspartate Receptor Antagonist in Healthy, Opioid-Naive Subjects: Results of Two Phase 1 Studies.
Galina Bernstein, Kelly Davis, Catherine Mills, Lu Wang, Michael McDonnell, Ottavio V Vitolo

J Clin Psychopharmacol· August 2019

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Biometric monitoring devices for assessing end points in clinical trials: developing an ecosystem.
Stephen P Arnerić, Jesse M Cedarbaum, Sean Khozin, Spyros Papapetropoulos, Derek L Hill, Ottavio V Vitolo

Nat Rev Drug Discov· October 2017

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In vivo measurement of PDE10A enzyme occupancy by positron emission tomography (PET) following single oral dose administration of PF-02545920 in healthy male subjects.
Marielle Delnomdedieu, Anton Forsberg, Adam Ogden, Patrik Fazio, Ching-Ray Yu, Ottavio V Vitolo

Neuropharmacology· May 2017

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Challenges, solutions, and recommendations for Alzheimer's disease combination therapy.
James A Hendrix, Randall J Bateman, H Robert Brashear, Cynthia Duggan, Maria C Carrillo, Ottavio V Vitolo

Alzheimers Dement· May 2016

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Efficacy and safety of a form of cranial electrical stimulation (CES) as an add-on intervention for treatment-resistant major depressive disorder: A three week double blind pilot study.
David Mischoulon, Marasha F De Jong, Ottavio V Vitolo, Cristina Cusin, Christina M Dording

J Psychiatr Res· November 2015

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S-adenosyl methionine (SAMe) versus escitalopram and placebo in major depression RCT: efficacy and effects of histamine and carnitine as moderators of response.
Jerome Sarris, George I Papakostas, Ottavio Vitolo, Maurizio Fava, David Mischoulon

J Affect Disord· August 2014

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Relationship between sleep disturbance and depression, anxiety, and functioning in college students.
Maren Nyer, Amy Farabaugh, Kiki Fehling, David Soskin, Daphne Holt, Ottavio Vitolo

Depress Anxiety· September 2013

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The effect of sildenafil on quality of life.
Christina M Dording, Rachel A LaRocca, Katherine A Hails, Ottavio V Vitolo, Stephen R Wisniewski

Ann Clin Psychiatry· February 2013

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A 12-week, randomized, double-blind, placebo-controlled, sequential parallel comparison trial of ziprasidone as monotherapy for major depressive disorder.
George I Papakostas, Ottavio V Vitolo, Waguih W Ishak, Mark H Rapaport, John M Zajecka

J Clin Psychiatry· December 2012

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Functional alterations in memory networks in early Alzheimer's disease.
Reisa A Sperling, Bradford C Dickerson, Maija Pihlajamaki, Patrizia Vannini, Peter S LaViolette, Ottavio V Vitolo

Neuromolecular Med· March 2010

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Protection against beta-amyloid induced abnormal synaptic function and cell death by Ginkgolide J.
Ottavio Vitolo, Bing Gong, Zixuan Cao, Hideki Ishii, Stanislav Jaracz

Neurobiol Aging· February 2009

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Amyloid beta peptide adversely affects spine number and motility in hippocampal neurons.
Brikha R Shrestha, Ottavio V Vitolo, Powrnima Joshi, Tamar Lordkipanidze, Michael Shelanski

Mol Cell Neurosci· November 2006

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Ubiquitin hydrolase Uch-L1 rescues beta-amyloid-induced decreases in synaptic function and contextual memory.
Bing Gong, Zixuan Cao, Ping Zheng, Ottavio V Vitolo, Shumin Liu

Cell· August 2006

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Amyloid-beta peptide inhibits activation of the nitric oxide/cGMP/cAMP-responsive element-binding protein pathway during hippocampal synaptic plasticity.
Daniela Puzzo, Ottavio Vitolo, Fabrizio Trinchese, Joel P Jacob, Agostino Palmeri

J Neurosci· July 2005

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Persistent improvement in synaptic and cognitive functions in an Alzheimer mouse model after rolipram treatment.
Bing Gong, Ottavio V Vitolo, Fabrizio Trinchese, Shumin Liu, Michael Shelanski

J Clin Invest· December 2004

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Dendrite and dendritic spine alterations in Alzheimer models.
Donna L Moolman, Ottavio V Vitolo, Jean-Paul G Vonsattel, Michael L Shelanski

J Neurocytol· May 2004

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Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease.
Elizabeth J Ryu, Heather P Harding, James M Angelastro, Ottavio V Vitolo, David Ron

J Neurosci· December 2002

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Amyloid beta -peptide inhibition of the PKA/CREB pathway and long-term potentiation: reversibility by drugs that enhance cAMP signaling.
Ottavio V Vitolo, Antonino Sant'Angelo, Vincenzo Costanzo, Fortunato Battaglia, Ottavio Arancio

Proc Natl Acad Sci U S A· October 2002

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