Publications by authors named "Owen Callaghan"

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Changes in plasma methionine-enkephalin levels associated with a cluster headache episode.
Aron D Mosnaim, Patricio Maturana, Owen H Callaghan, Marion E Wolf

Am J Ther· December 2014

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Rat brain-uptake index for phenylethylamine and various monomethylated derivatives.
Aron D Mosnaim, Owen H Callaghan, Thomas Hudzik, Marion E Wolf

Neurochem Res· April 2013

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Fragment-based drug discovery applied to Hsp90. Discovery of two lead series with high ligand efficiency.
Christopher W Murray, Maria G Carr, Owen Callaghan, Gianni Chessari, Miles Congreve

J Med Chem· August 2010

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Fragment-based discovery of mexiletine derivatives as orally bioavailable inhibitors of urokinase-type plasminogen activator.
Martyn Frederickson, Owen Callaghan, Gianni Chessari, Miles Congreve, Suzanna R Cowan

J Med Chem· January 2008

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Application of fragment-based lead generation to the discovery of novel, cyclic amidine beta-secretase inhibitors with nanomolar potency, cellular activity, and high ligand efficiency.
Philip D Edwards, Jeffrey S Albert, Mark Sylvester, David Aharony, Donald Andisik, Owen Callaghan

J Med Chem· November 2007

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Application of fragment screening by X-ray crystallography to beta-secretase.
Christopher W Murray, Owen Callaghan, Gianni Chessari, Anne Cleasby, Miles Congreve

J Med Chem· March 2007

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Application of fragment screening by X-ray crystallography to the discovery of aminopyridines as inhibitors of beta-secretase.
Miles Congreve, David Aharony, Jeffrey Albert, Owen Callaghan, James Campbell

J Med Chem· March 2007

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