Publications by authors named "Parantu Shah"

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MLH1 Mismatch Repair Deficiency Predicts Exceptional Response to Immune Checkpoint Inhibition in Clear-cell Renal Cell Carcinoma.
Mark T Dawidek, Lina Posada Calderon, Parantu K Shah, Rohan Mittal, Burcin Agridag Ucpinar

Eur Urol· November 2025

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Biomarker Analyses Investigating Disease Biology and Associations with Outcomes in the JAVELIN Merkel 200 Trial of Avelumab in Metastatic Merkel Cell Carcinoma.
Sandra P D'Angelo, Céleste Lebbé, Paul Nghiem, Andrew S Brohl, Thomas Mrowiec, Parantu Shah

Clin Cancer Res· October 2024

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Avelumab first-line maintenance in advanced urothelial carcinoma: Complete screening for prognostic and predictive factors using machine learning in the JAVELIN Bladder 100 phase 3 trial.
Juliane Manitz, Aslihan Gerhold-Ay, Pascal Kieslich, Parantu Shah, Thomas Mrowiec

Cancer Med· June 2024

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HLA-A*03 and response to immune checkpoint blockade in cancer: an epidemiological biomarker study.
Vivek Naranbhai, Mathias Viard, Michael Dean, Stefan Groha, David A Braun, Parantu Shah

Lancet Oncol· January 2022

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First-line avelumab in a cohort of 116 patients with metastatic Merkel cell carcinoma (JAVELIN Merkel 200): primary and biomarker analyses of a phase II study.
Sandra P D'Angelo, Celeste Lebbé, Laurent Mortier, Andrew S Brohl, Nicola Fazio, Parantu Shah

J Immunother Cancer· July 2021

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Avelumab in patients with previously treated metastatic Merkel cell carcinoma: long-term data and biomarker analyses from the single-arm phase 2 JAVELIN Merkel 200 trial.
Sandra P D'Angelo, Shailender Bhatia, Andrew S Brohl, Omid Hamid, Janice M Mehnert, Parantu Shah

J Immunother Cancer· May 2020

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Applications of machine learning in drug discovery and development.
Jessica Vamathevan, Dominic Clark, Paul Czodrowski, Ian Dunham, Edgardo Ferran, Parantu Shah

Nat Rev Drug Discov· June 2019

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Cross-talk between chromatin acetylation and SUMOylation of tripartite motif-containing protein 24 (TRIM24) impacts cell adhesion.
Srikanth Appikonda, Kaushik N Thakkar, Parantu K Shah, Sharon Y R Dent, Jannik N Andersen

J Biol Chem· May 2018

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TRIM28 and Interacting KRAB-ZNFs Control Self-Renewal of Human Pluripotent Stem Cells through Epigenetic Repression of Pro-differentiation Genes.
Urszula Oleksiewicz, Marta Gładych, Ayush T Raman, Holger Heyn, Elisabetta Mereu, Parantu K Shah

Stem Cell Reports· December 2017

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TRIM28 multi-domain protein regulates cancer stem cell population in breast tumor development.
Patrycja Czerwińska, Parantu K Shah, Katarzyna Tomczak, Marta Klimczak, Sylwia Mazurek

Oncotarget· January 2017

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In Vivo Functional Platform Targeting Patient-Derived Xenografts Identifies WDR5-Myc Association as a Critical Determinant of Pancreatic Cancer.
Alessandro Carugo, Giannicola Genovese, Sahil Seth, Luigi Nezi, Johnathon Lynn Rose, Parantu Krushnakant Shah

Cell Rep· June 2016

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The SMARCA2/4 ATPase Domain Surpasses the Bromodomain as a Drug Target in SWI/SNF-Mutant Cancers: Insights from cDNA Rescue and PFI-3 Inhibitor Studies.
Bhavatarini Vangamudi, Thomas A Paul, Parantu K Shah, Maria Kost-Alimova, Lisa Nottebaum

Cancer Res· September 2015

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Genetic events that limit the efficacy of MEK and RTK inhibitor therapies in a mouse model of KRAS-driven pancreatic cancer.
Piergiorgio Pettazzoni, Andrea Viale, Parantu Shah, Alessandro Carugo, Haoqiang Ying

Cancer Res· March 2015

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Computational characterisation of cancer molecular profiles derived using next generation sequencing.
Urszula Oleksiewicz, Katarzyna Tomczak, Jakub Woropaj, Monika Markowska, Piotr Stępniak, Parantu K Shah

Contemp Oncol (Pozn)· February 2015

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Editorial.
Maciej Wiznerowicz, Parantu K Shah, Jannik N Andersen

Contemp Oncol (Pozn)· January 2015

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Targeting poly(ADP-ribose) polymerase and the c-Myb-regulated DNA damage response pathway in castration-resistant prostate cancer.
Likun Li, Wenjun Chang, Guang Yang, Chengzhen Ren, Sanghee Park, Parantu K Shah

Sci Signal· May 2014

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Classify hyperdiploidy status of multiple myeloma patients using gene expression profiles.
Yingxiang Li, Xujun Wang, Haiyang Zheng, Chengyang Wang, Stéphane Minvielle, Parantu K Shah

PLoS One· October 2013

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The shaping and functional consequences of the dosage effect landscape in multiple myeloma.
Mehmet K Samur, Parantu K Shah, Xujun Wang, Stéphane Minvielle, Florence Magrangeas

BMC Genomics· October 2013

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canEvolve: a web portal for integrative oncogenomics.
Mehmet Kemal Samur, Zhenyu Yan, Xujun Wang, Qingyi Cao, Nikhil C Munshi, Parantu K Shah

PLoS One· August 2013

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Integrative analysis of gene and miRNA expression profiles with transcription factor-miRNA feed-forward loops identifies regulators in human cancers.
Zhenyu Yan, Parantu K Shah, Samir B Amin, Mehmet K Samur, Norman Huang

Nucleic Acids Res· September 2012

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A small molecule inhibitor of ubiquitin-specific protease-7 induces apoptosis in multiple myeloma cells and overcomes bortezomib resistance.
Dharminder Chauhan, Ze Tian, Benjamin Nicholson, K G Suresh Kumar, Bin Zhou, Parantu K Shah

Cancer Cell· September 2012

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Lessons from a decade of integrating cancer copy number alterations with gene expression profiles.
Norman Huang, Parantu K Shah, Cheng Li

Brief Bioinform· May 2012

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Determinants of antigenicity and specificity in immune response for protein sequences.
Yulong Wang, Wenjun Wu, Nicolas N Negre, Kevin P White, Cheng Li, Parantu K Shah

BMC Bioinformatics· June 2011

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The dChip survival analysis module for microarray data.
Samir B Amin, Parantu K Shah, Aimin Yan, Sophia Adamia, Stéphane Minvielle

BMC Bioinformatics· March 2011

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A cis-regulatory map of the Drosophila genome.
Nicolas Nègre, Christopher D Brown, Lijia Ma, Christopher Aaron Bristow, Steven W Miller, Parantu K Shah

Nature· March 2011

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