Publications by authors named "Paris Vail"

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CDK/cyclin dependencies define extreme cancer cell-cycle heterogeneity and collateral vulnerabilities.
Erik S Knudsen, Vishnu Kumarasamy, Ram Nambiar, Joel D Pearson, Paris Vail

Cell Rep· March 2022

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Functional Determinants of Cell Cycle Plasticity and Sensitivity to CDK4/6 Inhibition.
Vishnu Kumarasamy, Paris Vail, Ram Nambiar, Agnieszka K Witkiewicz, Erik S Knudsen

Cancer Res· March 2021

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Targeting dual signalling pathways in concert with immune checkpoints for the treatment of pancreatic cancer.
Erik S Knudsen, Vishnu Kumarasamy, Sejin Chung, Amanda Ruiz, Paris Vail

Gut· January 2021

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A Phase I Study of Ribociclib Plus Everolimus in Patients with Metastatic Pancreatic Adenocarcinoma Refractory to Chemotherapy.
Benjamin A Weinberg, Hongkun Wang, Agnieszka K Witkiewicz, John L Marshall, Aiwu R He, Paris Vail

J Pancreat Cancer· June 2020

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Interrogating Mutant Allele Expression via Customized Reference Genomes to Define Influential Cancer Mutations.
Adam D Grant, Paris Vail, Megha Padi, Agnieszka K Witkiewicz, Erik S Knudsen

Sci Rep· September 2019

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Cell cycle plasticity driven by MTOR signaling: integral resistance to CDK4/6 inhibition in patient-derived models of pancreatic cancer.
Erik S Knudsen, Vishnu Kumarasamy, Amanda Ruiz, Jared Sivinski, Sejin Chung, Paris Vail

Oncogene· May 2019

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Coordinately Targeting Cell-Cycle Checkpoint Functions in Integrated Models of Pancreatic Cancer.
Sejin Chung, Paris Vail, Agnieszka K Witkiewicz, Erik S Knudsen

Clin Cancer Res· April 2019

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Pancreatic cancer cell lines as patient-derived avatars: genetic characterisation and functional utility.
Erik S Knudsen, Uthra Balaji, Brian Mannakee, Paris Vail, Cody Eslinger

Gut· March 2018

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Composite analysis of immunological and metabolic markers defines novel subtypes of triple negative breast cancer.
Thomas A Adams, Paris J Vail, Amanda Ruiz, Mehri Mollaee, Peter A McCue

Mod Pathol· February 2018

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Targeting the Vulnerability of RB Tumor Suppressor Loss in Triple-Negative Breast Cancer.
Agnieszka K Witkiewicz, Sejin Chung, Rachel Brough, Paris Vail, Jorge Franco

Cell Rep· January 2018

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Stratification of Pancreatic Ductal Adenocarcinoma: Combinatorial Genetic, Stromal, and Immunologic Markers.
Erik S Knudsen, Paris Vail, Uthra Balaji, Hoai Ngo, Ihab W Botros

Clin Cancer Res· August 2017

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Biological specificity of CDK4/6 inhibitors: dose response relationship, in vivo signaling, and composite response signature.
Erik S Knudsen, Jack Hutcheson, Paris Vail, Agnieszka K Witkiewicz

Oncotarget· July 2017

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Assessment of in silico protein sequence analysis in the clinical classification of variants in cancer risk genes.
Iain D Kerr, Hannah C Cox, Kelsey Moyes, Brent Evans, Brianna C Burdett, Paris J Vail

J Community Genet· April 2017

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Comparison of locus-specific databases for BRCA1 and BRCA2 variants reveals disparity in variant classification within and among databases.
Paris J Vail, Brian Morris, Aric van Kan, Brianna C Burdett, Kelsey Moyes

J Community Genet· October 2015

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