Publications by authors named "Patrick Bray"

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Effects of CurraNZ, a New Zealand Blackcurrant Extract during 1 Hour of Treadmill Running in Female and Male Marathon des Sables Athletes in Hot Conditions: Two Case Studies.
Mark E T Willems, Patrick W Bray, Holly M Bassett, Tilly J Spurr, Andrew T West

J Funct Morphol Kinesiol· April 2024

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Dose prediction for repurposing nitazoxanide in SARS-CoV-2 treatment or chemoprophylaxis.
Rajith K R Rajoli, Henry Pertinez, Usman Arshad, Helen Box, Lee Tatham, Patrick G Bray

Br J Clin Pharmacol· April 2021

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Prioritization of Anti-SARS-Cov-2 Drug Repurposing Opportunities Based on Plasma and Target Site Concentrations Derived from their Established Human Pharmacokinetics.
Usman Arshad, Henry Pertinez, Helen Box, Lee Tatham, Rajith K R Rajoli, Patrick G Bray

Clin Pharmacol Ther· October 2020

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Dose prediction for repurposing nitazoxanide in SARS-CoV-2 treatment or chemoprophylaxis.
Rajith Kr Rajoli, Henry Pertinez, Usman Arshad, Helen Box, Lee Tatham, Patrick G Bray

medRxiv· May 2020

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Forgetting the madeleine: Proust and the neurosciences.
Patrick M Bray

Prog Brain Res· June 2014

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Loss of pH control in Plasmodium falciparum parasites subjected to oxidative stress.
Donelly A van Schalkwyk, Kevin J Saliba, Giancarlo A Biagini, Patrick G Bray, Kiaran Kirk

PLoS One· December 2013

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Glutathione transport: a new role for PfCRT in chloroquine resistance.
Eva-Maria Patzewitz, J Enrique Salcedo-Sora, Eleanor H Wong, Sonal Sethia, Paul A Stocks, Patrick G Bray

Antioxid Redox Signal· September 2013

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The molecular basis of folate salvage in Plasmodium falciparum: characterization of two folate transporters.
J Enrique Salcedo-Sora, Edwin Ochong, Susan Beveridge, David Johnson, Alexis Nzila, Patrick G Bray

J Biol Chem· December 2011

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Synthesis and antimalarial activities of a diverse set of triazole-containing furamidine analogues.
Olivier Berger, Archana Kaniti, Christophe Tran van Ba, Henri Vial, Stephen A Ward, Patrick G Bray

ChemMedChem· November 2011

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Sequence and gene expression of chloroquine resistance transporter (pfcrt) in the association of in vitro drugs resistance of Plasmodium falciparum.
Wanna Chaijaroenkul, Stephen A Ward, Mathirut Mungthin, David Johnson, Andrew Owen, Patrick G Bray

Malar J· February 2011

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Identification of a 1,2,4,5-tetraoxane antimalarial drug-development candidate (RKA 182) with superior properties to the semisynthetic artemisinins.
Paul M O'Neill, Richard K Amewu, Gemma L Nixon, Fatima Bousejra ElGarah, Mathirut Mungthin, Patrick G Bray

Angew Chem Int Ed Engl· August 2010

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An acid-loading chloride transport pathway in the intraerythrocytic malaria parasite, Plasmodium falciparum.
Roselani I Henry, Simon A Cobbold, Richard J W Allen, Asif Khan, Rhys Hayward, Patrick G Bray

J Biol Chem· June 2010

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Concentration-dependent effects and intracellular accumulation of HIV protease inhibitors in cultured CD4 T cells and primary human lymphocytes.
Omar Janneh, Patrick G Bray, Elizabeth Jones, Christoph Wyen, Peter Chiba

J Antimicrob Chemother· May 2010

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Plant homologs of the Plasmodium falciparum chloroquine-resistance transporter, PfCRT, are required for glutathione homeostasis and stress responses.
Spencer C Maughan, Maciej Pasternak, Narelle Cairns, Guy Kiddle, Thorsten Brach, Patrick Bray

Proc Natl Acad Sci U S A· February 2010

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The accumulation and metabolism of zidovudine in 3T3-F442A pre-adipocytes.
Omar Janneh, Andrew Owen, Patrick G Bray, David J Back, Munir Pirmohamed

Br J Pharmacol· January 2010

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Antitumour and antimalarial activity of artemisinin-acridine hybrids.
Michael Jones, Amy E Mercer, Paul A Stocks, Louise J I La Pensée, Rick Cosstick, Patrick G Bray

Bioorg Med Chem Lett· April 2009

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Semi-synthetic and synthetic 1,2,4-trioxaquines and 1,2,4-trioxolaquines: synthesis, preliminary SAR and comparison with acridine endoperoxide conjugates.
Nuna C P Araújo, Victoria Barton, Michael Jones, Paul A Stocks, Stephen A Ward, Patrick G Bray

Bioorg Med Chem Lett· April 2009

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Synthesis, antimalarial activity, and preclinical pharmacology of a novel series of 4'-fluoro and 4'-chloro analogues of amodiaquine. Identification of a suitable "back-up" compound for N-tert-butyl isoquine.
Paul M O'Neill, Alison E Shone, Deborah Stanford, Gemma Nixon, Eghbaleh Asadollahy, Patrick G Bray

J Med Chem· April 2009

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Plasmodium falciparum and dihydrofolate reductase I164L mutations in Africa.
Alisa P Alker, Jonathan J Juliano, Steven R Meshnick, Andrew Owen, Edwin Ochong, Patrick G Bray

Antimicrob Agents Chemother· April 2009

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Candidate selection and preclinical evaluation of N-tert-butyl isoquine (GSK369796), an affordable and effective 4-aminoquinoline antimalarial for the 21st century.
Paul M O'Neill, B Kevin Park, Alison E Shone, James L Maggs, Phillip Roberts, Patrick G Bray

J Med Chem· March 2009

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Glycerol: an unexpected major metabolite of energy metabolism by the human malaria parasite.
Lu-Yun Lian, Mohammed Al-Helal, Abd Majid Roslaini, Nicholas Fisher, Patrick G Bray

Malar J· March 2009

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Plasmodium falciparum strains harboring dihydrofolate reductase with the I164L mutation are absent in Malawi and Zambia even under antifolate drug pressure.
Edwin Ochong, David J Bell, David J Johnson, Umberto D'Alessandro, Modest Mulenga, Patrick G Bray

Antimicrob Agents Chemother· November 2008

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Acridinediones: selective and potent inhibitors of the malaria parasite mitochondrial bc1 complex.
Giancarlo A Biagini, Nicholas Fisher, Neil Berry, Paul A Stocks, Brigitte Meunier, Patrick G Bray

Mol Pharmacol· May 2008

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A comprehensive model of purine uptake by the malaria parasite Plasmodium falciparum: identification of four purine transport activities in intraerythrocytic parasites.
Neils B Quashie, Dominique Dorin-Semblat, Patrick G Bray, Giancarlo A Biagini, Christian Doerig

Biochem J· April 2008

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Accumulation of the antimalarial microtubule inhibitors trifluralin and vinblastine by Plasmodium falciparum.
Julie Ann Naughton, Ruth Hughes, Patrick Bray, Angus Bell

Biochem Pharmacol· April 2008

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