Publications by authors named "Patrick Caspers"

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Discovery and Structure-Activity Relationship of Cadazolid: A First-In-Class Quinoxolidinone Antibiotic for the Treatment of Infection.
Georg Rueedi, Philippe Panchaud, Astrid Friedli, Jean-Luc Specklin, Christian Hubschwerlen, Patrick Caspers

J Med Chem· June 2024

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Synthesis and Structure-Activity Relationship of Xenocoumacin 1 and Analogues as Inhibitors of Ribosomal Protein Synthesis.
Cornelia Zumbrunn, Daniela Krüsi, Christina Stamm, Patrick Caspers, Daniel Ritz

ChemMedChem· March 2021

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Structural basis of translation inhibition by cadazolid, a novel quinoxolidinone antibiotic.
Alain Scaiola, Marc Leibundgut, Daniel Boehringer, Patrick Caspers, Daniel Bur

Sci Rep· April 2019

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Total Synthesis and Biological Evaluation of the Glycosylated Macrocyclic Antibiotic Mangrolide A.
Hiromu Hattori, Joel Roesslein, Patrick Caspers, Katja Zerbe, Hideki Miyatake-Ondozabal

Angew Chem Int Ed Engl· August 2018

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Different Resistance Mechanisms for Cadazolid and Linezolid in Clostridium difficile Found by Whole-Genome Sequencing Analysis.
Patrick Caspers, Hans H Locher, Philippe Pfaff, Sarah Diggelmann, Georg Rueedi

Antimicrob Agents Chemother· August 2017

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Investigations of the mode of action and resistance development of cadazolid, a new antibiotic for treatment of Clostridium difficile infections.
Hans H Locher, Patrick Caspers, Thierry Bruyère, Susanne Schroeder, Philippe Pfaff

Antimicrob Agents Chemother· September 2014

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Asparaginyl-tRNA synthetase pre-transfer editing assay.
Franck Danel, Patrick Caspers, Claude Nuoffer, Michael Härtlein, Michael A Kron

Curr Drug Discov Technol· March 2011

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Propenylamide and propenylsulfonamide cephalosporins as a novel class of anti-MRSA beta-lactams.
Jens Pohlmann, Natalya I Vasilevich, Andrei I Glushkov, Laurenz Kellenberger, Stuart Shapiro, Patrick Caspers

Bioorg Med Chem Lett· August 2010

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In vitro activities of three new dihydrofolate reductase inhibitors against clinical isolates of gram-positive bacteria.
Karen E Bowker, Patrick Caspers, Bérengère Gaucher, Alasdair P MacGowan

Antimicrob Agents Chemother· November 2009

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In vitro and in vivo properties of dihydrophthalazine antifolates, a novel family of antibacterial drugs.
Patrick Caspers, Luc Bury, Bérangère Gaucher, Jutta Heim, Stuart Shapiro

Antimicrob Agents Chemother· September 2009

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Antistaphylococcal activity of dihydrophthalazine antifolates, a family of novel antibacterial drugs.
Catherine Clark, Lois M Ednie, Gengrong Lin, Kathy Smith, Klaudia Kosowska-Shick, Patrick Caspers

Antimicrob Agents Chemother· April 2009

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Structure-activity relationships of different beta-lactam antibiotics against a soluble form of Enterococcus faecium PBP5, a type II bacterial transpeptidase.
Andrea M Hujer, Malgosia Kania, Thomas Gerken, Vernon E Anderson, John D Buynak, Patrick Caspers

Antimicrob Agents Chemother· February 2005

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Impact of specific pbp5 mutations on expression of beta-lactam resistance in Enterococcus faecium.
Louis B Rice, Samuel Bellais, Lenore L Carias, Rebecca Hutton-Thomas, Robert A Bonomo, Patrick Caspers

Antimicrob Agents Chemother· August 2004

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