Publications by authors named "Jens Pohlmann"

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Dual Inhibition of the Lactate Transporters MCT1 and MCT4 Is Synthetic Lethal with Metformin due to NAD+ Depletion in Cancer Cells.
Don Benjamin, Dimitri Robay, Sravanth K Hindupur, Jens Pohlmann, Marco Colombi

Cell Rep· December 2018

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The novel microtubule-destabilizing drug BAL27862 binds to the colchicine site of tubulin with distinct effects on microtubule organization.
Andrea E Prota, Franck Danel, Felix Bachmann, Katja Bargsten, Rubén M Buey, Jens Pohlmann

J Mol Biol· April 2014

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Propenylamide and propenylsulfonamide cephalosporins as a novel class of anti-MRSA beta-lactams.
Jens Pohlmann, Natalya I Vasilevich, Andrei I Glushkov, Laurenz Kellenberger, Stuart Shapiro

Bioorg Med Chem Lett· August 2010

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Discovery of the novel antithrombotic agent 5-chloro-N-({(5S)-2-oxo-3- [4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene- 2-carboxamide (BAY 59-7939): an oral, direct factor Xa inhibitor.
Susanne Roehrig, Alexander Straub, Jens Pohlmann, Thomas Lampe, Josef Pernerstorfer

J Med Chem· September 2005

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Pyrrolidinedione derivatives as antibacterial agents with a novel mode of action.
Jens Pohlmann, Thomas Lampe, Mitsuyuki Shimada, Peter G Nell, Josef Pernerstorfer

Bioorg Med Chem Lett· February 2005

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Identification and characterization of the first class of potent bacterial acetyl-CoA carboxylase inhibitors with antibacterial activity.
Christoph Freiberg, Nina A Brunner, Guido Schiffer, Thomas Lampe, Jens Pohlmann

J Biol Chem· June 2004

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New class of bacterial phenylalanyl-tRNA synthetase inhibitors with high potency and broad-spectrum activity.
Dieter Beyer, Hein-Peter Kroll, Rainer Endermann, Guido Schiffer, Stephan Siegel, Jens Pohlmann

Antimicrob Agents Chemother· February 2004

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Synthesis of Unsaturated Nine-Membered Ring Ethers (Δ -Oxonenes) Containing a Z- or E-Configurated Double Bond: Thermodynamic versus Kinetic Control in Palladium-Catalyzed Allylic Cyclizations.
Jens Pohlmann, Christopher Sabater, H M R Hoffmann

Angew Chem Int Ed Engl· March 1998

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