Publications by authors named "Patrick D Bhola"

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The Siren Song of Synergy.
Patrick D Bhola, Anthony Letai

Blood Cancer Discov· March 2024

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Sequential apoptotic and multiplexed proteomic evaluation of single cancer cells.
Emmalyn Lecky, Atreyi Mukherji, Rebecca German, Gabriella Antonellis, Jia-Ren Lin, Patrick D Bhola

Sci Adv· June 2023

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Identification of Novel Therapeutic Targets for Fibrolamellar Carcinoma Using Patient-Derived Xenografts and Direct-from-Patient Screening.
Gadi Lalazar, David Requena, Lavoisier Ramos-Espiritu, Denise Ng, Patrick D Bhola

Cancer Discov· October 2021

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Metabolic perturbations sensitize triple-negative breast cancers to apoptosis induced by BH3 mimetics.
Veerle W Daniels, Jason J Zoeller, Nick van Gastel, Kelley E McQueeney, Salma Parvin, Patrick D Bhola

Sci Signal· June 2021

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High-throughput dynamic BH3 profiling may quickly and accurately predict effective therapies in solid tumors.
Patrick D Bhola, Eman Ahmed, Jennifer L Guerriero, Ewa Sicinska, Emily Su

Sci Signal· June 2020

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Pooled Genomic Screens Identify Anti-apoptotic Genes as Targetable Mediators of Chemotherapy Resistance in Ovarian Cancer.
Elizabeth H Stover, Maria B Baco, Ofir Cohen, Yvonne Y Li, Elizabeth L Christie, Patrick D Bhola

Mol Cancer Res· November 2019

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Developmental Regulation of Mitochondrial Apoptosis by c-Myc Governs Age- and Tissue-Specific Sensitivity to Cancer Therapeutics.
Kristopher A Sarosiek, Cameron Fraser, Nathiya Muthalagu, Patrick D Bhola, Weiting Chang

Cancer Cell· January 2017

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Functionally identifiable apoptosis-insensitive subpopulations determine chemoresistance in acute myeloid leukemia.
Patrick D Bhola, Brenton G Mar, R Coleman Lindsley, Jeremy A Ryan, Leah J Hogdal

J Clin Invest· October 2016

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Mitochondria-Judges and Executioners of Cell Death Sentences.
Patrick D Bhola, Anthony Letai

Mol Cell· March 2016

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Determinism and divergence of apoptosis susceptibility in mammalian cells.
Patrick D Bhola, Sanford M Simon

J Cell Sci· December 2009

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Spatial and temporal dynamics of mitochondrial membrane permeability waves during apoptosis.
Patrick D Bhola, Alexa L Mattheyses, Sanford M Simon

Biophys J· October 2009

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