Publications by authors named "Patrick Harriott"

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Insulin secretory and antidiabetic actions of Heritiera fomes bark together with isolation of active phytomolecules.
Prawej Ansari, Peter R Flatt, Patrick Harriott, Yasser H A Abdel-Wahab

PLoS One· April 2022

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Anti-hyperglycaemic and insulin-releasing effects of leaves and isolation and characterisation of active compounds.
Prawej Ansari, Peter R Flatt, Patrick Harriott, Yasser H A Abdel-Wahab

Br J Nutr· October 2021

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Insulinotropic and antidiabetic properties of Eucalyptus citriodora leaves and isolation of bioactive phytomolecules.
Prawej Ansari, Peter R Flatt, Patrick Harriott, Yasser H A Abdel-Wahab

J Pharm Pharmacol· July 2021

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Identification of Multiple Pancreatic and Extra-Pancreatic Pathways Underlying the Glucose-Lowering Actions of Bark in Type-2 Diabetes and Isolation of Active Phytoconstituents.
Prawej Ansari, Peter R Flatt, Patrick Harriott, J M A Hannan, Yasser H A Abdel-Wahab

Plants (Basel)· June 2021

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Evaluation of the Antidiabetic and Insulin Releasing Effects of , Including Isolation and Characterization of Active Phytochemicals.
Prawej Ansari, Peter R Flatt, Patrick Harriott, Yasser H A Abdel-Wahab

Plants (Basel)· October 2020

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Administration of an acylated GLP-1 and GIP preparation provides added beneficial glucose-lowering and insulinotropic actions over single incretins in mice with Type 2 diabetes and obesity.
Victor A Gault, Barry D Kerr, Patrick Harriott, Peter R Flatt

Clin Sci (Lond)· August 2011

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A modified Tat peptide for selective intracellular delivery of macromolecules.
Diarmaid J Murphy, Brian Walker, Brett Greer, Patrick Harriott, S Lorraine Martin

J Pharm Pharmacol· May 2011

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Glucagon-like peptide-1 analogues enhance synaptic plasticity in the brain: a link between diabetes and Alzheimer's disease.
Paula L McClean, Victor A Gault, Patrick Harriott, Christian Hölscher

Eur J Pharmacol· March 2010

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Comparison of the anti-diabetic effects of GIP- and GLP-1-receptor activation in obese diabetic (ob/ob) mice: studies with DPP IV resistant N-AcGIP and exendin(1-39)amide.
Nigel Irwin, Paula L McClean, Roslyn S Cassidy, Finbarr P M O'harte, Brian D Green, Patrick Harriott

Diabetes Metab Res Rev· October 2007

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Impairments of hippocampal synaptic plasticity induced by aggregated beta-amyloid (25-35) are dependent on stimulation-protocol and genetic background.
Simon Gengler, Victor A Gault, Patrick Harriott, Christian Hölscher

Exp Brain Res· June 2007

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Antagonistic effects of two novel GIP analogs, (Hyp3)GIP and (Hyp3)GIPLys16PAL, on the biological actions of GIP and longer-term effects in diabetic ob/ob mice.
Finbarr P M O'Harte, Kerry Hunter, Victor A Gault, Nigel Irwin, Brian D Green, Patrick Harriott

Am J Physiol Endocrinol Metab· June 2007

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Characterisation and biological activity of Glu3 amino acid substituted GIP receptor antagonists.
Victor A Gault, Kerry Hunter, Nigel Irwin, Brian D Green, Brett Greer, Patrick Harriott

Arch Biochem Biophys· May 2007

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Beneficial effects of sub-chronic activation of glucagon-like peptide-1 (GLP-1) receptors on deterioration of glucose homeostasis and insulin secretion in aging mice.
Nigel Irwin, Paula L McClean, Patrick Harriott, Peter R Flatt

Exp Gerontol· April 2007

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Soluble beta-amyloid[25-35] reversibly impairs hippocampal synaptic plasticity and spatial learning.
Christian Holscher, Simon Gengler, Victor A Gault, Patrick Harriott, Hanspeter A Mallot

Eur J Pharmacol· April 2007

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Characterisation and glucoregulatory actions of a novel acylated form of the (Pro3)GIP receptor antagonist in type 2 diabetes.
Victor A Gault, Kerry Hunter, Nigel Irwin, Brett Greer, Brian D Green, Patrick Harriott

Biol Chem· February 2007

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Evaluation of the antidiabetic activity of DPP IV resistant N-terminally modified versus mid-chain acylated analogues of glucose-dependent insulinotropic polypeptide.
Nigel Irwin, Gillian C Clarke, Brian D Green, Brett Greer, Patrick Harriott

Biochem Pharmacol· September 2006

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Novel glucagon-like peptide-1 (GLP-1) analog (Val8)GLP-1 results in significant improvements of glucose tolerance and pancreatic beta-cell function after 3-week daily administration in obese diabetic (ob/ob) mice.
Brian D Green, Kerry S Lavery, Nigel Irwin, Finbarr P M O'harte, Patrick Harriott

J Pharmacol Exp Ther· August 2006

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Effects on glucose homeostasis and insulin secretion of long term activation of the glucose-dependent insulinotropic polypeptide (GIP) receptor by N-AcGIP(LysPAL37) in normal mice.
Nigel Irwin, Brian D Green, Victor A Gault, Roslyn S Cassidy, Finbarr P M O'Harte, Patrick Harriott

Peptides· April 2006

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GIP(Lys16PAL) and GIP(Lys37PAL): novel long-acting acylated analogues of glucose-dependent insulinotropic polypeptide with improved antidiabetic potential.
Nigel Irwin, Finbarr P M O'Harte, Victor A Gault, Brian D Green, Brett Greer, Patrick Harriott

J Med Chem· February 2006

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A novel, long-acting agonist of glucose-dependent insulinotropic polypeptide suitable for once-daily administration in type 2 diabetes.
Nigel Irwin, Brian D Green, Mark H Mooney, Brett Greer, Patrick Harriott

J Pharmacol Exp Ther· September 2005

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Chemical ablation of gastric inhibitory polypeptide receptor action by daily (Pro3)GIP administration improves glucose tolerance and ameliorates insulin resistance and abnormalities of islet structure in obesity-related diabetes.
Victor A Gault, Nigel Irwin, Brian D Green, Jane T McCluskey, Brett Greer, Patrick Harriott

Diabetes· August 2005

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Antidiabetic potential of two novel fatty acid derivatised, N-terminally modified analogues of glucose-dependent insulinotropic polypeptide (GIP): N-AcGIP(LysPAL16) and N-AcGIP(LysPAL37).
Nigel Irwin, Victor A Gault, Brian D Green, Brett Greer, Patrick Harriott

Biol Chem· July 2005

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Degradation, insulin secretion, and antihyperglycemic actions of two palmitate-derivitized N-terminal pyroglutamyl analogues of glucose-dependent insulinotropic polypeptide.
Nigel Irwin, Brian D Green, Victor A Gault, Brett Greer, Patrick Harriott

J Med Chem· February 2005

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Effects of short-term chemical ablation of the GIP receptor on insulin secretion, islet morphology and glucose homeostasis in mice.
Nigel Irwin, Victor A Gault, Brian D Green, Brett Greer, Jane T McCluskey, Patrick Harriott

Biol Chem· September 2004

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A strategy for designing inhibitors of alpha-synuclein aggregation and toxicity as a novel treatment for Parkinson's disease and related disorders.
Omar M A El-Agnaf, Katerina E Paleologou, Brett Greer, Abdulmawala M Abogrein, Jenny E King, Patrick Harriott

FASEB J· August 2004

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