Publications by authors named "Patrick Leroy"

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Discovery and optimization of pyrazolopyrimidine sulfamates as ATG7 inhibitors.
Shih-Chung Huang, Sharmila Adhikari, James E Brownell, Emily F Calderwood, Jouhara Chouitar, Patrick J LeRoy

Bioorg Med Chem· October 2020

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Automated High-Throughput Flow Cytometry for High-Content Screening in Antibody Development.
Yana Wang, Tomoki Yoshihara, Samson King, Tinh Le, Patrick Leroy

SLAS Discov· August 2018

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Identification of a lung cancer cell line deficient in atg7-dependent autophagy.
Jonathan Mandelbaum, Neil Rollins, Pooja Shah, Doug Bowman, Janice Y Lee, Patrick LeRoy

Autophagy· June 2015

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MLN8054 and Alisertib (MLN8237): Discovery of Selective Oral Aurora A Inhibitors.
Todd B Sells, Ryan Chau, Jeffrey A Ecsedy, Rachel E Gershman, Kara Hoar, Patrick J LeRoy

ACS Med Chem Lett· June 2015

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Characterization of Alisertib (MLN8237), an investigational small-molecule inhibitor of aurora A kinase using novel in vivo pharmacodynamic assays.
Mark G Manfredi, Jeffrey A Ecsedy, Arijit Chakravarty, Lee Silverman, Mengkun Zhang, Patrick J Leroy

Clin Cancer Res· December 2011

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Genome-wide siRNA screen for modulators of cell death induced by proteasome inhibitor bortezomib.
Siquan Chen, Jonathan L Blank, Theodore Peters, Xiaozhen J Liu, David M Rappoli, Patrick J Leroy

Cancer Res· June 2010

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Localization of human TACC3 to mitotic spindles is mediated by phosphorylation on Ser558 by Aurora A: a novel pharmacodynamic method for measuring Aurora A activity.
Patrick J LeRoy, John J Hunter, Kara M Hoar, Krissy E Burke, Vaishali Shinde

Cancer Res· June 2007

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Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase.
Mark G Manfredi, Jeffrey A Ecsedy, Kristan A Meetze, Suresh K Balani, Olga Burenkova, Patrick J LeRoy

Proc Natl Acad Sci U S A· March 2007

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Detection of activity centers in cellular pathways using transcript profiling.
Joel Pradines, Laura Rudolph-Owen, John Hunter, Patrick Leroy, Michael Cary, Christophe Leroy

J Biopharm Stat· August 2004

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