Publications by authors named "Paul Erhardt"

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E
Evaluation of the Recent Dynamics for Funding Medicinal Chemistry Projects in Academia. Results of a Survey Conducted by IUPAC Division VII (Chemistry and Human Health).
Ayelet Rothstein, Mukund Chorghade, Hassan Ibrahim, A Ganesan, Paul W Erhardt

J Med Chem· February 2025

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Synthesis and Evaluation of PPARδ Agonists That Promote Osteogenesis in a Human Mesenchymal Stem Cell Culture and in a Mouse Model of Human Osteoporosis.
Brian J Kress, Dong Hyun Kim, Jared R Mayo, Jeffery T Farris, Benjamin Heck, Paul W Erhardt

J Med Chem· May 2021

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Repurposing metformin, simvastatin and digoxin as a combination for targeted therapy for pancreatic ductal adenocarcinoma.
Shi-He Liu, Juehua Yu, Justin F Creeden, Jeffrey M Sutton, Stephen Markowiak, Paul Erhardt

Cancer Lett· October 2020

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Investigating the Potential to Deliver and Maintain Plasma and Brain Levels of a Novel Practically Insoluble Methuosis Inducing Anticancer Agent 5-Methoxy MOMIPP Through an Injectable In Situ Forming Thermoresponsive Hydrogel Formulation.
Frank Oppong, Zehui Li, Ehsan Akbari Fakhrabadi, Tanvi Raorane, Paras M Giri, Paul W Erhardt

J Pharm Sci· September 2020

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Bilirubin remodels murine white adipose tissue by reshaping mitochondrial activity and the coregulator profile of peroxisome proliferator-activated receptor α.
Darren M Gordon, Kari L Neifer, Abdul-Rizaq Ali Hamoud, Charles F Hawk, Andrea L Nestor-Kalinoski, Paul W Erhardt

J Biol Chem· July 2020

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BIRC5 is a target for molecular imaging and detection of human pancreatic cancer.
Shi-He Liu, Yeahwa Hong, Stephen Markowiak, Robbi Sanchez, Justin Creeden, Paul Erhardt

Cancer Lett· August 2019

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6-MOMIPP, a novel brain-penetrant anti-mitotic indolyl-chalcone, inhibits glioblastoma growth and viability.
Shengnan Du, Jeffrey G Sarver, Christopher J Trabbic, Paul W Erhardt, Allen Schroering

Cancer Chemother Pharmacol· February 2019

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The JNK signaling pathway plays a key role in methuosis (non-apoptotic cell death) induced by MOMIPP in glioblastoma.
Zehui Li, Nneka E Mbah, Jean H Overmeyer, Jeffrey G Sarver, Sage George, Paul W Erhardt

BMC Cancer· January 2019

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Targeting the DNA Repair Endonuclease ERCC1-XPF with Green Tea Polyphenol Epigallocatechin-3-Gallate (EGCG) and Its Prodrug to Enhance Cisplatin Efficacy in Human Cancer Cells.
Joshua R Heyza, Sanjeevani Arora, Hao Zhang, Kayla L Conner, Wen Lei, Paul Erhardt

Nutrients· November 2018

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Corrigendum: Leukocyte integrin Mac-1 regulates thrombosis via interaction with platelet GPIbα.
Yunmei Wang, Huiyun Gao, Can Shi, Paul W Erhardt, Alexander Pavlovsky

Nat Commun· July 2017

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Leukocyte integrin Mac-1 regulates thrombosis via interaction with platelet GPIbα.
Yunmei Wang, Huiyun Gao, Can Shi, Paul W Erhardt, Alexander Pavlovsky

Nat Commun· May 2017

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Synthesis and biological evaluation of isomeric methoxy substitutions on anti-cancer indolyl-pyridinyl-propenones: Effects on potency and mode of activity.
Christopher J Trabbic, Sage M George, Evan M Alexander, Shengnan Du, Jennifer M Offenbacher, Paul W Erhardt

Eur J Med Chem· October 2016

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Total Synthesis of (±)-Glyceollin II and a Dihydro Derivative.
Neha Malik, Zhaoqi Zhang, Paul Erhardt

J Nat Prod· December 2015

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Synthesis and biological evaluation of indolyl-pyridinyl-propenones having either methuosis or microtubule disruption activity.
Christopher J Trabbic, Jean H Overmeyer, Evan M Alexander, Emily J Crissman, Heather M Kvale, Paul W Erhardt

J Med Chem· March 2015

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Differential Induction of Cytoplasmic Vacuolization and Methuosis by Novel 2-Indolyl-Substituted Pyridinylpropenones.
Christopher J Trabbic, Heather M Dietsch, Evan M Alexander, Peter I Nagy, Michael W Robinson, Paul W Erhardt

ACS Med Chem Lett· January 2014

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Practical synthesis of a chromene analog for use as a retinoic acid receptor alpha antagonist lead compound.
Rachael Jetson, Neha Malik, Amarjit Luniwal, Venkatesh Chari, Manohar Ratnam, Paul Erhardt

Eur J Med Chem· May 2013

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Early stage efficacy and toxicology screening for antibiotics and enzyme inhibitors.
Jeffrey G Sarver, Jill A Trendel, Nicole R Bearss, Lin Wang, Amarjit Luniwal, Paul W Erhardt

J Biomol Screen· June 2012

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Glyceollins, soy isoflavone phytoalexins, improve oral glucose disposal by stimulating glucose uptake.
Stephen M Boué, Iryna A Isakova, Matthew E Burow, Heping Cao, Deepak Bhatnagar, Paul W Erhardt

J Agric Food Chem· June 2012

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Molecular docking and enzymatic evaluation to identify selective inhibitors of aspartate semialdehyde dehydrogenase.
Amarjit Luniwal, Lin Wang, Alexander Pavlovsky, Paul W Erhardt, Ronald E Viola

Bioorg Med Chem· May 2012

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On the interaction of aliphatic amines and ammonium ions with carboxylic acids in solution and in receptor pockets.
Peter I Nagy, Paul W Erhardt

J Phys Chem B· May 2012

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Synthesis and evaluation of indole-based chalcones as inducers of methuosis, a novel type of nonapoptotic cell death.
Michael W Robinson, Jean H Overmeyer, Ashley M Young, Paul W Erhardt, William A Maltese

J Med Chem· March 2012

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Hypoxia activated prodrugs of a 9-aza-anthrapyrazole derivative that has promising anticancer activity.
Mohammad H El-Dakdouki, Nicholas Adamski, Lecia Foster, Miles P Hacker, Paul W Erhardt

J Med Chem· December 2011

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Syntheses of 2,3-diarylated 2H-benzo[e][1,2]thiazine 1,1-dioxides and their 3,4-dihydro derivatives, and assessment of their inhibitory activity against MCF-7 breast cancer cells.
Yuan-Yuan Shan, Cheng-Mei Zhang, Long-Qiang Tang, Zhao-Peng Liu, Nicole R Bearss, Paul W Erhardt

Med Chem· November 2011

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Biomimetic syntheses and antiproliferative activities of racemic, natural (-), and unnnatural (+) glyceollin I.
Rahul S Khupse, Jeffrey G Sarver, Jill A Trendel, Nicole R Bearss, Michael D Reese, Paul W Erhardt

J Med Chem· May 2011

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Theoretical studies of salt-bridge formation by amino acid side chains in low and medium polarity environments.
Peter I Nagy, Paul W Erhardt

J Phys Chem B· December 2010

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