Publications by authors named "Paul Kussie"

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Cardiovascular and hemodynamic consequences of recombinant placental growth factor administration in Guinea pigs.
Adelene Y Tan, Ken Kearney, Courtney Jenkins, S Ananth Karumanchi, Walter Bee, Paul Kussie

Hypertens Pregnancy· May 2022

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Administration of recombinant human placental growth factor decreases blood pressure in obese hypertensive pregnant rats.
Ana C Palei, Adelene Y Tan, Woo S Joo, Paul Kussie, Christopher D Anderson

J Hypertens· November 2020

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Placental Growth Factor Administration Abolishes Placental Ischemia-Induced Hypertension.
Frank T Spradley, Adelene Y Tan, Woo S Joo, Garrett Daniels, Paul Kussie

Hypertension· April 2016

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The structural basis for the function of two anti-VEGF receptor 2 antibodies.
Matthew C Franklin, Elizabeth C Navarro, Yujie Wang, Sheetal Patel, Pinki Singh, Paul Kussie

Structure· August 2011

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Antitumor Activity of IMC-038525, a Novel Oral Tubulin Polymerization Inhibitor.
Maria Carolina Tuma, Asra Malikzay, Xiaohu Ouyang, David Surguladze, James Fleming, Paul Kussie

Transl Oncol· October 2010

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Lack of detection of agonist activity by antibodies to platelet-derived growth factor receptor alpha in a subset of normal and systemic sclerosis patient sera.
Nick Loizos, Leah Lariccia, Jami Weiner, Heather Griffith, Francesco Boin, Paul Kussie

Arthritis Rheum· April 2009

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Arylphthalazines as potent, and orally bioavailable inhibitors of VEGFR-2.
Matthew A J Duncton, Eugene L Piatnitski Chekler, Reeti Katoch-Rouse, Dan Sherman, Wai C Wong, Paul Kussie

Bioorg Med Chem· January 2009

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Structural basis for EGF receptor inhibition by the therapeutic antibody IMC-11F8.
Shiqing Li, Paul Kussie, Kathryn M Ferguson

Structure· February 2008

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Monoclonal antibody antagonists of hypothalamic FGFR1 cause potent but reversible hypophagia and weight loss in rodents and monkeys.
Haijun D Sun, Maria Malabunga, James R Tonra, Roberto DiRenzo, Francine E Carrick, Paul Kussie

Am J Physiol Endocrinol Metab· March 2007

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Development of heparanase inhibitors for anti-cancer therapy.
Hua-Quan Miao, Hu Liu, Elizabeth Navarro, Paul Kussie, Zhenping Zhu

Curr Med Chem· September 2006

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N-(4-{[4-(1H-Benzoimidazol-2-yl)-arylamino]-methyl}-phenyl)-benzamide derivatives as small molecule heparanase inhibitors.
Yong-Jiang Xu, Hua-Quan Miao, Weitao Pan, Elizabeth C Navarro, James R Tonra, Paul Kussie

Bioorg Med Chem Lett· January 2006

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1-[4-(1H-Benzoimidazol-2-yl)-phenyl]-3-[4-(1H-benzoimidazol-2-yl)-phenyl]-urea derivatives as small molecule heparanase inhibitors.
Weitao Pan, Hua-Quan Miao, Yong-Jiang Xu, Elizabeth C Navarro, James R Tonra, Paul Kussie

Bioorg Med Chem Lett· January 2006

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Pyrimido-oxazepine as a versatile template for the development of inhibitors of specific kinases.
Weitao Pan, Hu Liu, Yong-Jiang Xu, Xin Chen, Ki Hwan Kim, Paul Kussie

Bioorg Med Chem Lett· December 2005

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Synthesis and structure-activity relationships of 1,2,4-triazoles as a novel class of potent tubulin polymerization inhibitors.
Xiaohu Ouyang, Xiaoling Chen, Evgueni L Piatnitski, Alexander S Kiselyov, Hai-Ying He, Paul Kussie

Bioorg Med Chem Lett· December 2005

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Identification of a transiently exposed VE-cadherin epitope that allows for specific targeting of an antibody to the tumor neovasculature.
Chad May, Jacqueline F Doody, Rashed Abdullah, Paul Balderes, Xiaohong Xu, Paul Kussie

Blood· June 2005

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Conservation of receptor antagonist anti-tumor activity by epidermal growth factor receptor antibody expressed in transgenic corn seed.
Dale L Ludwig, Larry Witte, Daniel J Hicklin, Marie Prewett, Rajiv Bassi, Paul Kussie

Hum Antibodies· April 2005

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Structural basis for inhibition of the epidermal growth factor receptor by cetuximab.
Shiqing Li, Karl R Schmitz, Philip D Jeffrey, Jed J W Wiltzius, Paul Kussie

Cancer Cell· April 2005

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Targeting the platelet-derived growth factor receptor alpha with a neutralizing human monoclonal antibody inhibits the growth of tumor xenografts: implications as a potential therapeutic target.
Nick Loizos, Yan Xu, Jim Huber, Meilin Liu, Dan Lu, Paul Kussie

Mol Cancer Ther· March 2005

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Heparanase promotes the spontaneous metastasis of myeloma cells to bone.
Yang Yang, Veronica Macleod, Manali Bendre, Yan Huang, Allison M Theus, Paul Kussie

Blood· February 2005

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Suppression of leukemia expressing wild-type or ITD-mutant FLT3 receptor by a fully human anti-FLT3 neutralizing antibody.
Yiwen Li, Hongli Li, Mei-Nai Wang, Dan Lu, Rajiv Bassi, Paul Kussie

Blood· August 2004

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High heparanase activity in multiple myeloma is associated with elevated microvessel density.
Thomas Kelly, Hua-Quan Miao, Yang Yang, Elizabeth Navarro, Paul Kussie

Cancer Res· December 2003

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A fully human monoclonal antibody to the insulin-like growth factor I receptor blocks ligand-dependent signaling and inhibits human tumor growth in vivo.
Douglas Burtrum, Zhenping Zhu, Dan Lu, Donna Marie Anderson, Marie Prewett, Paul Kussie

Cancer Res· December 2003

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Cloning, expression, and purification of mouse heparanase.
Hua-Quan Miao, Elizabeth Navarro, Sheetal Patel, David Sargent, Henry Koo, Paul Kussie

Protein Expr Purif· December 2002

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Selective targeting of angiogenic tumor vasculature by vascular endothelial-cadherin antibody inhibits tumor growth without affecting vascular permeability.
Fang Liao, Jacqueline F Doody, Jay Overholser, Bridget Finnerty, Rajiv Bassi, Paul Kussie

Cancer Res· May 2002

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