Publications by authors named "Paul Spellman"

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Cell free RNA detection of pancreatic cancer in pre diagnostic high risk and symptomatic patients.
Travis W Moore, Elias Spiliotopoulos, Rowan L Callahan, C Ward Kirschbaum, Conner F Bailey, Paul T Spellman

Nat Commun· August 2025

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Autosomal Allelic Inactivation: Variable Replication and Dosage Sensitivity.
Michael B Heskett, Athanasios E Vouzas, Brian Johnstone, Krister P Freese, Phillip A Yates, Paul T Spellman

bioRxiv· August 2025

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Pan-cancer immune and stromal deconvolution predicts clinical outcomes and mutation profiles.
Bhavneet Bhinder, Verena Friedl, Sunantha Sethuraman, Davide Risso, Kami E Chiotti, Paul Spellman

Sci Rep· July 2025

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Diverse Genomes, Shared Health: Insights from a Health System Biobank.
Roni Haas, Michael P Margolis, Angela Wei, Takafumi N Yamaguchi, Jeffrey Feng, Paul T Spellman

medRxiv· June 2025

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The History of Chromosomal Instability in Genome-Doubled Tumors.
Toby M Baker, Siqi Lai, Andrew R Lynch, Tom Lesluyes, Haixi Yan, Paul T Spellman

Cancer Discov· October 2024

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Multiplex imaging of localized prostate tumors reveals altered spatial organization of AR-positive cells in the microenvironment.
Çiğdem Ak, Zeynep Sayar, Guillaume Thibault, Erik A Burlingame, M J Kuykendall, Paul T Spellman

iScience· September 2024

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ASAR lncRNAs control DNA replication timing through interactions with multiple hnRNP/RNA binding proteins.
Mathew Thayer, Michael B Heskett, Leslie G Smith, Paul T Spellman, Phillip A Yates

Elife· June 2024

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Mutation of SIVA, a candidate metastasis gene identified from clonally related bilateral breast cancers, promotes breast cancer cell spread in vitro and in vivo.
Anke Vermehren-Schmaedick, Myron Peto, Wendy Wagoner, Kami E Chiotti, Elizabeth Ramsey, Paul Spellman

PLoS One· May 2024

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The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma.
Christopher J Ricketts, Aguirre A De Cubas, Huihui Fan, Christof C Smith, Martin Lang, Paul T Spellman

Cell Rep· April 2024

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HER2 heterogeneity and treatment response-associated profiles in HER2-positive breast cancer in the NCT02326974 clinical trial.
Zheqi Li, Otto Metzger Filho, Giuseppe Viale, Patrizia dell'Orto, Leila Russo, Paul T Spellman

J Clin Invest· February 2024

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Novel recruitment approaches and operational results for a statewide population Cohort for cancer research: The Healthy Oregon Project.
Zhenzhen Zhang, Autumn Shafer, Katie Johnson-Camacho, Andrew Adey, Pavana Anur, Paul T Spellman

J Clin Transl Sci· January 2024

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Population screening shows risk of inherited cancer and familial hypercholesterolemia in Oregon.
Timothy D O'Brien, Amiee B Potter, Catherine C Driscoll, Gregory Goh, John H Letaw, Paul T Spellman

Am J Hum Genet· August 2023

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An open protocol for modeling T Cell Clonotype repertoires using TCRβ CDR3 sequences.
Burcu Gurun, Wesley Horton, Dhaarini Murugan, Biqing Zhu, Patrick Leyshock, Paul T Spellman

BMC Genomics· June 2023

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Defining clonal hematopoiesis of indeterminate potential: evolutionary dynamics and detection under aging and inflammation.
Elisabeth A Goldman, Paul T Spellman, Anupriya Agarwal

Cold Spring Harb Mol Case Stud· April 2023

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Corrigendum: Blood, toil, and taxoteres: Biological determinants of treatment-induced ctDNA dynamics for interpreting tumor response.
Christopher T Boniface, Paul T Spellman

Pathol Oncol Res· March 2023

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Supervised learning of high-confidence phenotypic subpopulations from single-cell data.
Tao Ren, Canping Chen, Alexey V Danilov, Susan Liu, Xiangnan Guan, Paul T Spellman

bioRxiv· March 2023

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Author Correction: The evolutionary history of 2,658 cancers.
Moritz Gerstung, Clemency Jolly, Ignaty Leshchiner, Stefan C Dentro, Santiago Gonzalez, Paul T Spellman

Nature· February 2023

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An open protocol for modeling T Cell Clonotype repertoires using TCRβ CDR3 sequences.
Burcu Gurun, Wesley Horton, Dhaarini Murugan, Biqing Zhu, Patrick Leyshock, Paul T Spellman

Res Sq· February 2023

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Epigenetic control of chromosome-associated lncRNA genes essential for replication and stability.
Michael B Heskett, Athanasios E Vouzas, Leslie G Smith, Phillip A Yates, Christopher Boniface, Paul T Spellman

Nat Commun· October 2022

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Blood, toil, and taxoteres: Biological determinants of treatment-induced ctDNA dynamics for interpreting tumor response.
Christopher T Boniface, Paul T Spellman

Pathol Oncol Res· June 2022

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Identifying phenotype-associated subpopulations by integrating bulk and single-cell sequencing data.
Duanchen Sun, Xiangnan Guan, Amy E Moran, Ling-Yun Wu, David Z Qian, Paul T Spellman

Nat Biotechnol· April 2022

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Plasma cell-free RNA profiling distinguishes cancers from pre-malignant conditions in solid and hematologic malignancies.
Breeshey Roskams-Hieter, Hyun Ji Kim, Pavana Anur, Josiah T Wagner, Rowan Callahan, Paul T Spellman

NPJ Precis Oncol· April 2022

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An omic and multidimensional spatial atlas from serial biopsies of an evolving metastatic breast cancer.
Brett E Johnson, Allison L Creason, Jayne M Stommel, Jamie M Keck, Swapnil Parmar, Paul T Spellman

Cell Rep Med· February 2022

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Epigenetic loss of heterogeneity from low to high grade localized prostate tumours.
Sebnem Ece Eksi, Alex Chitsazan, Zeynep Sayar, George V Thomas, Andrew J Fields, Paul T Spellman

Nat Commun· December 2021

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Differential Allelic Expression among Long Non-Coding RNAs.
Michael B Heskett, Paul T Spellman, Mathew J Thayer

Noncoding RNA· October 2021

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