Publications by authors named "Paulo Lin"

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Treatment of a metabolic liver disease in mice with a transient prime editing approach.
Tanja Rothgangl, András Tálas, Eleonora I Ioannidi, Yanik Weber, Desirée Böck, Elina Andrea Villiger, Paulo J C Lin

Nat Biomed Eng· October 2025

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Computationally designed mRNA-launched protein nanoparticle immunogens elicit protective antibody and T cell responses in mice.
Grace G Hendricks, Lilit Grigoryan, Mary Jane Navarro, Nicholas J Catanzaro, Miranda L Hubbard, Paulo J C Lin

Sci Transl Med· October 2025

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mRNA delivery of genetically encoded mosaic-8 pan-sarbecovirus RBD vaccines.
Alexander A Cohen, Jennifer R Keeffe, Lusineh Manasyan, Indeever Madireddy, Ange-Célia I Priso Fils, Paulo J C Lin

bioRxiv· October 2025

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Bivalent mRNA booster encoding virus-like particles elicits potent polyclass RBD antibodies in pre-vaccinated mice.
Chengcheng Fan, Alexander A Cohen, Kim-Marie A Dam, Annie V Rorick, Ange-Célia I Priso Fils, Paulo J C Lin

bioRxiv· August 2025

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Predicting adenine base editing efficiencies in different cellular contexts by deep learning.
Lucas Kissling, Amina Mollaysa, Sharan Janjuha, Nicolas Mathis, Kim F Marquart, Paulo J C Lin

Genome Biol· May 2025

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Author Correction: Lipid nanoparticles (LNP) induce activation and maturation of antigen presenting cells in young and aged individuals.
Jennifer Connors, David Joyner, Nathan J Mege, Gina M Cusimano, Matthew R Bell, Paulo J C Lin

Commun Biol· February 2025

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Mosaic sarbecovirus nanoparticles elicit cross-reactive responses in pre-vaccinated animals.
Alexander A Cohen, Jennifer R Keeffe, Ariën Schiepers, Sandra E Dross, Allison J Greaney, Paulo J C Lin

Cell· October 2024

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mRNA lipid nanoparticles expressing cell-surface cleavage independent HIV Env trimers elicit autologous tier-2 neutralizing antibodies.
Javier Guenaga, Mehrdad Alirezaei, Yu Feng, Mohamad-Gabriel Alameh, Wen-Hsin Lee, Paulo Lin

Front Immunol· August 2024

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Immunotherapeutic effects of specific and nonspecific mRNA-lipid nanoparticles in a mouse model of HDM-induced airway inflammation.
Chanatip Thanasarnthungcharoen, Supapich Chanasit, Laurence Fievez, Theerayuth Kaewamatawong, Piyachat Patniboon, Paulo J C Lin

Allergy· July 2024

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Exploring Mechanisms of Lipid Nanoparticle-Mucus Interactions in Healthy and Cystic Fibrosis Conditions.
Belal Tafech, Mohammad-Reza Rokhforouz, Jerry Leung, Molly Mh Sung, Paulo Jc Lin

Adv Healthc Mater· July 2024

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Computationally designed mRNA-launched protein nanoparticle vaccines.
Grace G Hendricks, Lilit Grigoryan, Mary Jane Navarro, Nicholas J Catanzaro, Miranda L Hubbard, Paulo J C Lin

bioRxiv· July 2024

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Mosaic sarbecovirus nanoparticles elicit cross-reactive responses in pre-vaccinated animals.
Alexander A Cohen, Jennifer R Keeffe, Ariën Schiepers, Sandra E Dross, Allison J Greaney, Paulo J C Lin

bioRxiv· May 2024

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Author Correction: A Pvs25 mRNA vaccine induces complete and durable transmission-blocking immunity to Plasmodium vivax.
Nawapol Kunkeaw, Wang Nguitragool, Eizo Takashima, Niwat Kangwanrangsan, Hiromi Muramatsu, Paulo J C Lin

NPJ Vaccines· February 2024

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Multivalent cytomegalovirus glycoprotein B nucleoside modified mRNA vaccines did not demonstrate a greater antibody breadth.
Hsuan-Yuan Wang, Leike Li, Cody S Nelson, Richard Barfield, Sarah Valencia, Paulo J C Lin

NPJ Vaccines· February 2024

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The Regulation of Nucleic Acid Vaccine Responses by the Microbiome.
Andrew M F Johnson, Kevin Hager, Mohamad-Gabriel Alameh, Phuong Van, Nicole Potchen, Paulo J C Lin, James G Kublin

J Immunol· December 2023

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A Pvs25 mRNA vaccine induces complete and durable transmission-blocking immunity to Plasmodium vivax.
Nawapol Kunkeaw, Wang Nguitragool, Eizo Takashima, Niwat Kangwanrangsan, Hiromi Muramatsu, Paulo J C Lin

NPJ Vaccines· December 2023

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Author Correction: mRNA-LNP expressing PfCSP and Pfs25 vaccine candidates targeting infection and transmission of Plasmodium falciparum.
Clifford T H Hayashi, Yi Cao, Leor C Clark, Abhai K Tripathi, Fidel Zavala, Paulo J C Lin

NPJ Vaccines· August 2023

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ESCRT recruitment to SARS-CoV-2 spike induces virus-like particles that improve mRNA vaccines.
Magnus A G Hoffmann, Zhi Yang, Kathryn E Huey-Tubman, Alexander A Cohen, Priyanthi N P Gnanapragasam, Paulo J C Lin

Cell· May 2023

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Molecular fate-mapping of serum antibody responses to repeat immunization.
Ariën Schiepers, Marije F L van 't Wout, Allison J Greaney, Trinity Zang, Hiromi Muramatsu, Paulo J C Lin

Nature· March 2023

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Single immunizations of self-amplifying or non-replicating mRNA-LNP vaccines control HPV-associated tumors in mice.
Jamile Ramos da Silva, Karine Bitencourt Rodrigues, Guilherme Formoso Pelegrin, Natiely Silva Sales, Hiromi Muramatsu, Ana Carolina Ramos Moreno, Katalin Karikó, Paulo J C Lin

Sci Transl Med· March 2023

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Restoration of Motor Function through Delayed Intraspinal Delivery of Human IL-10-Encoding Nucleoside-Modified mRNA after Spinal Cord Injury.
László Gál, Tamás Bellák, Annamária Marton, Zoltán Fekécs, Drew Weissman, Paulo J C Lin

Research (Wash D C)· March 2023

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A pan-variant mRNA-LNP T cell vaccine protects HLA transgenic mice from mortality after infection with SARS-CoV-2 Beta.
Brandon Carter, Pinghan Huang, Ge Liu, Yuejin Liang, Paulo J C Lin, Lindsay G A McKay

Front Immunol· March 2023

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Lipid nanoparticles (LNP) induce activation and maturation of antigen presenting cells in young and aged individuals.
Jennifer Connors, David Joyner, Nathan J Mege, Gina M Cusimano, Matthew R Bell, Paulo J C Lin

Commun Biol· February 2023

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The Regulation of Nucleic Acid Vaccine Responses by the Microbiome.
Andrew M F Johnson, Kevin Hager, Mohamad-Gabriel Alameh, Phuong Van, Nicole Potchen, Paulo J C Lin, James G Kublin

bioRxiv· February 2023

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ESCRT recruitment to mRNA-encoded SARS-CoV-2 spike induces virus-like particles and enhanced antibody responses.
Magnus A G Hoffmann, Zhi Yang, Kathryn E Huey-Tubman, Alexander A Cohen, Priyanthi N P Gnanapragasam, Paulo J C Lin

bioRxiv· December 2022

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