Publications by authors named "Peter Bruno"

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Exploitable mechanisms of antibody and CAR mediated macrophage cytotoxicity.
Tianyi Liu, Meng Zhang, Tatyanah Farsh, Haolong Li, Audrey Kishishita, Peter M Bruno

Nat Commun· July 2025

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PepTCR-Net: prediction of multi-class antigen peptides by T-cell receptor sequences with deep learning.
Phi Le, Leah Ung, Hai Yang, Anwen Huang, Tao He, Peter Bruno

Brief Bioinform· July 2025

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A multi-subunit autophagic capture complex facilitates degradation of ER stalled MHC-I in pancreatic cancer.
Marine Berquez, Alexander L Li, Matthew A Luy, Anthony C Venida, Thomas O'Loughlin, Peter M Bruno

bioRxiv· October 2024

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The genomics revolution comes to the immunopeptidome.
Peter M Bruno

Genes Immun· June 2024

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High-throughput, targeted MHC class I immunopeptidomics using a functional genetics screening platform.
Peter M Bruno, Richard T Timms, Nouran S Abdelfattah, Yumei Leng, Felipe J N Lelis

Nat Biotechnol· July 2023

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Author Correction: Nanoparticle conjugates of a highly potent toxin enhance safety and circumvent platinum resistance in ovarian cancer.
Ruogu Qi, Yongheng Wang, Peter M Bruno, Haihua Xiao, Yingjie Yu

Nat Commun· April 2020

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The primary mechanism of cytotoxicity of the chemotherapeutic agent CX-5461 is topoisomerase II poisoning.
Peter M Bruno, Mengrou Lu, Kady A Dennis, Haider Inam, Connor J Moore

Proc Natl Acad Sci U S A· February 2020

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Publisher Correction: Nanoparticle conjugates of a highly potent toxin enhance safety and circumvent platinum resistance in ovarian cancer.
Ruogu Qi, Yongheng Wang, Peter M Bruno, Haihua Xiao, Yingjie Yu

Nat Commun· February 2018

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Nanoparticle conjugates of a highly potent toxin enhance safety and circumvent platinum resistance in ovarian cancer.
Ruogu Qi, Yongheng Wang, Peter M Bruno, Haihua Xiao, Yingjie Yu

Nat Commun· December 2017

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Aneuploid Cell Survival Relies upon Sphingolipid Homeostasis.
Yun-Chi Tang, Hui Yuwen, Kaiying Wang, Peter M Bruno, Kevin Bullock

Cancer Res· October 2017

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Induction of Necroptosis in Cancer Stem Cells using a Nickel(II)-Dithiocarbamate Phenanthroline Complex.
Marie Flamme, Paul B Cressey, Chunxin Lu, Peter M Bruno, Arvin Eskandari

Chemistry· July 2017

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A subset of platinum-containing chemotherapeutic agents kills cells by inducing ribosome biogenesis stress.
Peter M Bruno, Yunpeng Liu, Ga Young Park, Junko Murai, Catherine E Koch

Nat Med· April 2017

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The breast cancer stem cell potency of copper(ii) complexes bearing nonsteroidal anti-inflammatory drugs and their encapsulation using polymeric nanoparticles.
Arvin Eskandari, Janine N Boodram, Paul B Cressey, Chunxin Lu, Peter M Bruno

Dalton Trans· November 2016

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Mechanistic Studies of the Anticancer Activity of An Octahedral Hexanuclear Pt(II) Cage.
Yao-Rong Zheng, Kogularamanan Suntharalingam, Peter M Bruno, Wei Lin, Weixue Wang

Inorganica Chim Acta· October 2016

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The Potent Inhibitory Effect of a Naproxen-Appended Cobalt(III)-Cyclam Complex on Cancer Stem Cells.
Paul B Cressey, Arvin Eskandari, Peter M Bruno, Chunxin Lu, Michael T Hemann

Chembiochem· September 2016

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Using an RNAi Signature Assay To Guide the Design of Three-Drug-Conjugated Nanoparticles with Validated Mechanisms, In Vivo Efficacy, and Low Toxicity.
Jonathan C Barnes, Peter M Bruno, Hung V-T Nguyen, Longyan Liao, Jenny Liu

J Am Chem Soc· September 2016

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Versatile in vivo regulation of tumor phenotypes by dCas9-mediated transcriptional perturbation.
Christian J Braun, Peter M Bruno, Max A Horlbeck, Luke A Gilbert, Jonathan S Weissman

Proc Natl Acad Sci U S A· July 2016

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Correction to "A Pt(IV) Pro-drug Preferentially Targets Indoleamine-2,3-dioxygenase, Providing Enhanced Ovarian Cancer Immuno-Chemotherapy".
Samuel G Awuah, Yao-Rong Zheng, Peter M Bruno, Michael T Hemann, Stephen J Lippard

J Am Chem Soc· March 2016

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Breast Cancer Stem Cell Potent Copper(II)-Non-Steroidal Anti-Inflammatory Drug Complexes.
Janine N Boodram, Iain J Mcgregor, Peter M Bruno, Paul B Cressey, Michael T Hemann

Angew Chem Int Ed Engl· February 2016

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A Pt(IV) Pro-drug Preferentially Targets Indoleamine-2,3-dioxygenase, Providing Enhanced Ovarian Cancer Immuno-Chemotherapy.
Samuel G Awuah, Yao-Rong Zheng, Peter M Bruno, Michael T Hemann, Stephen J Lippard

J Am Chem Soc· December 2015

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Necroptosis-inducing rhenium(V) oxo complexes.
Kogularamanan Suntharalingam, Samuel G Awuah, Peter M Bruno, Timothy C Johnstone, Fang Wang

J Am Chem Soc· March 2015

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A breast cancer stem cell-selective, mammospheres-potent osmium(VI) nitrido complex.
Kogularamanan Suntharalingam, Wei Lin, Timothy C Johnstone, Peter M Bruno, Yao-Rong Zheng

J Am Chem Soc· October 2014

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Bidentate ligands on osmium(VI) nitrido complexes control intracellular targeting and cell death pathways.
Kogularamanan Suntharalingam, Timothy C Johnstone, Peter M Bruno, Wei Lin, Michael T Hemann

J Am Chem Soc· September 2013

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Predicting cancer drug mechanisms of action using molecular network signatures.
Justin R Pritchard, Peter M Bruno, Michael T Hemann, Douglas A Lauffenburger

Mol Biosyst· July 2013

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A new fracture assessment approach coupling HR-pQCT imaging and fracture mechanics-based finite element modeling.
Ani Ural, Peter Bruno, Bin Zhou, X Tony Shi, X Edward Guo

J Biomech· April 2013

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