Publications by authors named "Peter Coward"

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5
5-Alkyl-2-urea-Substituted Pyridines: Identification of Efficacious Glucokinase Activators with Improved Properties.
Todd J Kohn, Xiaohui Du, SuJen Lai, YuMei Xiong, Renee Komorowski, Peter Coward

ACS Med Chem Lett· July 2016

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Novel Series of Potent Glucokinase Activators Leading to the Discovery of AM-2394.
Paul J Dransfield, Vatee Pattaropong, Sujen Lai, Zice Fu, Todd J Kohn, Peter Coward

ACS Med Chem Lett· July 2016

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Characterization of a novel glucokinase activator in rat and mouse models.
Min Lu, Pingping Li, Gautam Bandyopadhyay, William Lagakos, Walter E Dewolf, Peter Coward

PLoS One· January 2015

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C5-Alkyl-2-methylurea-Substituted Pyridines as a New Class of Glucokinase Activators.
Xiaohui Du, Ronald J Hinklin, Yumei Xiong, Paul Dransfield, Jaehyeon Park, Peter Coward

ACS Med Chem Lett· December 2014

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Structure-assisted discovery of the first non-retinoid ligands for Retinol-Binding Protein 4.
Yingcai Wang, Richard Connors, Pingchen Fan, Xiaodong Wang, Zhongyu Wang, Peter Coward

Bioorg Med Chem Lett· July 2014

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Discovery and optimization of 5-(2-((1-(phenylsulfonyl)-1,2,3,4-tetrahydroquinolin-7-yl)oxy)pyridin-4-yl)-1,2,4-oxadiazoles as novel gpr119 agonists.
Yingcai Wang, Ming Yu, Jiang Zhu, Jian Ken Zhang, Frank Kayser, Peter Coward

Bioorg Med Chem Lett· February 2014

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Discovery and optimization of N-(3-(1,3-dioxo-2,3-dihydro-1H-pyrrolo[3,4-c]pyridin-4-yloxy)phenyl)benzenesulfonamides as novel GPR119 agonists.
Ming Yu, Jian Ken Zhang, Yingcai Wang, Jiang Zhu, Frank Kayser, Peter Coward

Bioorg Med Chem Lett· January 2014

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Discovery and optimization of arylsulfonyl 3-(pyridin-2-yloxy)anilines as novel GPR119 agonists.
Jian Ken Zhang, An-Rong Li, Ming Yu, Yingcai Wang, Jiang Zhu, Peter Coward

Bioorg Med Chem Lett· June 2013

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Discovery and optimization of a series of liver X receptor antagonists.
XianYun Jiao, David J Kopecky, Ben Fisher, Derek E Piper, Marc Labelle, Peter Coward

Bioorg Med Chem Lett· September 2012

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Discovery of a new binding mode for a series of liver X receptor agonists.
David J Kopecky, Xian Yun Jiao, Ben Fisher, Sharon McKendry, Marc Labelle, Peter Coward

Bioorg Med Chem Lett· April 2012

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Discovery and optimization of a novel Neuromedin B receptor antagonist.
Jiasheng Fu, Stephen J Shuttleworth, Richard V Connors, Anne Chai, Peter Coward

Bioorg Med Chem Lett· August 2009

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Identification of a PPARdelta agonist with partial agonistic activity on PPARgamma.
Richard V Connors, Zhulun Wang, Martin Harrison, Alex Zhang, Malgorzata Wanska, Peter Coward

Bioorg Med Chem Lett· July 2009

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Identification and characterization of a non-retinoid ligand for retinol-binding protein 4 which lowers serum retinol-binding protein 4 levels in vivo.
Alykhan Motani, Zhulun Wang, Marion Conn, Karen Siegler, Ying Zhang, Peter Coward

J Biol Chem· March 2009

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Application of an allosteric model to describe the interactions among retinol binding protein 4, transthyretin, and small molecule retinol binding protein 4 ligands.
Peter Coward, Marion Conn, Jie Tang, Fei Xiong, Anthony Menjares

Anal Biochem· January 2009

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Effects of peroxisome proliferator-activated receptor alpha/delta agonists on HDL-cholesterol in vervet monkeys.
Jeanne M Wallace, Margrit Schwarz, Peter Coward, Jonathan Houze, Janet K Sawyer

J Lipid Res· May 2005

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Identification and optimization of novel partial agonists of neuromedin B receptor using parallel synthesis.
Stephen J Shuttleworth, Mike E Lizarzaburu, Anne Chai, Peter Coward

Bioorg Med Chem Lett· June 2004

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Tools for dissecting signaling pathways in vivo: receptors activated solely by synthetic ligands.
Kimberly Scearce-Levie, Peter Coward, Charles H Redfern, Bruce R Conklin

Methods Enzymol· February 2002

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