Publications by authors named "Peter D Williams"

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Neonatal Suckling, Oxytocin, and Early Infant Attachment to the Mother.
Raymond Nowak, Frédéric Lévy, Elodie Chaillou, Fabien Cornilleau, Juliette Cognié, Peter D Williams

Front Endocrinol (Lausanne)· May 2021

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Design and Synthesis of Piperazine Sulfonamide Cores Leading to Highly Potent HIV-1 Protease Inhibitors.
Christopher J Bungard, Peter D Williams, Jurgen Schulz, Catherine M Wiscount, M Katharine Holloway

ACS Med Chem Lett· December 2017

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Discovery of highly potent and selective orexin 1 receptor antagonists (1-SORAs) suitable for in vivo interrogation of orexin 1 receptor pharmacology.
Craig A Stump, Andrew J Cooke, Joseph Bruno, Tamara D Cabalu, Anthony L Gotter, Peter D Williams

Bioorg Med Chem Lett· December 2016

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Discovery of MK-8718, an HIV Protease Inhibitor Containing a Novel Morpholine Aspartate Binding Group.
Christopher J Bungard, Peter D Williams, Jeanine E Ballard, David J Bennett, Christian Beaulieu

ACS Med Chem Lett· July 2016

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Discovery of piperidine ethers as selective orexin receptor antagonists (SORAs) inspired by filorexant.
Izzat T Raheem, Michael J Breslin, Joseph Bruno, Tamara D Cabalu, Andrew Cooke, Peter D Williams

Bioorg Med Chem Lett· February 2015

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Design, synthesis and SAR of a series of 1,3,5-trisubstituted benzenes as thrombin inhibitors.
Richard C A Isaacs, Christina L Newton, Kellie J Cutrona, Swati P Mercer, Linda S Payne, Peter D Williams

Bioorg Med Chem Lett· March 2011

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Potent and selective HIV-1 ribonuclease H inhibitors based on a 1-hydroxy-1,8-naphthyridin-2(1H)-one scaffold.
Peter D Williams, Donnette D Staas, Shankar Venkatraman, H Marie Loughran, Rowena D Ruzek

Bioorg Med Chem Lett· November 2010

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Structural basis for the inhibition of RNase H activity of HIV-1 reverse transcriptase by RNase H active site-directed inhibitors.
Hua-Poo Su, Youwei Yan, G Sridhar Prasad, Robert F Smith, Christopher L Daniels, Peter D Williams

J Virol· August 2010

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Purification of untagged HIV-1 reverse transcriptase by affinity chromatography.
Meiqing Lu, Winnie Ngo, Ye Mei, Vandna Munshi, Christine Burlein, Peter D Williams

Protein Expr Purif· June 2010

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10-Hydroxy-7,8-dihydropyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-1,9(2H,6H)-diones: potent, orally bioavailable HIV-1 integrase strand-transfer inhibitors with activity against integrase mutants.
Catherine M Wiscount, Peter D Williams, Lekhanh O Tran, Mark W Embrey, Thorsten E Fisher

Bioorg Med Chem Lett· August 2008

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Design and synthesis of substituted 4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxamides, novel HIV-1 integrase inhibitors.
H Marie Langford, Peter D Williams, Carl F Homnick, Joseph P Vacca, Peter J Felock

Bioorg Med Chem Lett· January 2008

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Dihydroxypyridopyrazine-1,6-dione HIV-1 integrase inhibitors.
John S Wai, Boyoung Kim, Thorsten E Fisher, Linghang Zhuang, Mark W Embrey, Peter D Williams

Bioorg Med Chem Lett· October 2007

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Discovery of potent, selective 4-fluoroproline-based thrombin inhibitors with improved metabolic stability.
Donnette D Staas, Kelly L Savage, Vanessa L Sherman, Heidi L Shimp, Terry A Lyle, Peter D Williams

Bioorg Med Chem· October 2006

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Tetrazole thioacetanilides: potent non-nucleoside inhibitors of WT HIV reverse transcriptase and its K103N mutant.
Ester Muraglia, Olaf D Kinzel, Ralph Laufer, Michael D Miller, Gregory Moyer, Peter D Williams

Bioorg Med Chem Lett· May 2006

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Development of an oxazolopyridine series of dual thrombin/factor Xa inhibitors via structure-guided lead optimization.
James Z Deng, Daniel R McMasters, Philippe M A Rabbat, Peter D Williams, Craig A Coburn

Bioorg Med Chem Lett· October 2005

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9-hydroxyazafluorenes and their use in thrombin inhibitors.
Kenneth J Stauffer, Peter D Williams, Harold G Selnick, Philippe G Nantermet, Christina L Newton

J Med Chem· April 2005

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Low molecular weight thrombin inhibitors with excellent potency, metabolic stability, and oral bioavailability.
Matthew M Morrissette, Kenneth J Stauffer, Peter D Williams, Terry A Lyle, Joseph P Vacca

Bioorg Med Chem Lett· August 2004

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Discovery and evaluation of potent P1 aryl heterocycle-based thrombin inhibitors.
Mary Beth Young, James C Barrow, Kristen L Glass, George F Lundell, Christina L Newton, Peter D Williams

J Med Chem· June 2004

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Metabolism-directed optimization of 3-aminopyrazinone acetamide thrombin inhibitors. Development of an orally bioavailable series containing P1 and P3 pyridines.
Christopher S Burgey, Kyle A Robinson, Terry A Lyle, Philip E J Sanderson, S Dale Lewis, Peter D Williams

J Med Chem· February 2003

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A nonpeptide oxytocin receptor antagonist radioligand highly selective for human receptors.
Wei Lemaire, Julie A O'Brien, Maryann Burno, Ashok G Chaudhary, Dennis C Dean, Peter D Williams, David L Williams

Eur J Pharmacol· August 2002

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