Publications by authors named "Peter Langfelder"

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Dendritome mapping reveals the spatial organization of striatal neuron morphology.
Chang Sin Park, Ming Yan, Muye Zhu, Masood A Akram, Nicholas N Foster, Peter Langfelder

Nat Neurosci· December 2025

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Gene signature for response prediction to immunotherapy and prognostic markers in metastatic urothelial carcinoma.
Peter Langfelder, En-Tni Lin, Yi-Ta Tsai, Tai-Lung Cha, Grace S Shieh

Front Immunol· December 2025

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Striatal pathology in Spinocerebellar Ataxia Type 1 mice: A comparative study with Huntington's disease.
Pragya Goel, Praseuth Yang, Lisa Duvick, Orion Rainwater, Shannah Serres, Peter Langfelder

bioRxiv· December 2025

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A rare genetic variant confers resistance to neurodegeneration across multiple neurological disorders by augmenting selective autophagy.
Katherine R Croce, Christopher Ng, Serihy Pankiv, Eddy Albarran, Peter Langfelder

Neuron· November 2025

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Distinct mismatch-repair complex genes set neuronal CAG-repeat expansion rate to drive selective pathogenesis in HD mice.
Nan Wang, Shasha Zhang, Peter Langfelder, Lalini Ramanathan, Fuying Gao

Cell· March 2025

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Dendritome Mapping Unveils Spatial Organization of Striatal D1/D2-Neuron Morphology.
Chang Sin Park, Ming Yan, Muye Zhu, Masood A Akram, Nicholas N Foster, Peter Langfelder

bioRxiv· October 2024

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Msh3 and Pms1 Set Neuronal CAG-repeat Migration Rate to Drive Selective Striatal and Cortical Pathogenesis in HD Mice.
Nan Wang, Shasha Zhang, Peter Langfelder, Lalini Ramanathan, Mary Plascencia

bioRxiv· July 2024

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Decreased but persistent epigenetic age acceleration is associated with changes in T-cell subsets after initiation of highly active antiretroviral therapy in persons living with HIV.
Mary E Sehl, Elizabeth Crabb Breen, Roger Shih, Fengxue Li, Joshua Zhang, Peter Langfelder

Front Bioinform· May 2024

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Erratum: Accelerated aging with HIV begins at the time of initial HIV infection.
Elizabeth Crabb Breen, Mary E Sehl, Roger Shih, Peter Langfelder, Ruibin Wang

iScience· August 2023

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BAC Transgenic Expression of Human TREM2-R47H Remodels Amyloid Plaques but Unable to Reprogram Plaque-associated Microglial Reactivity in 5xFAD Mice.
C Y Daniel Lee, Amberlene J De La Rocha, Kellie Inouye, Peter Langfelder, Anthony Daggett

bioRxiv· August 2023

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Mapping brain gene coexpression in daytime transcriptomes unveils diurnal molecular networks and deciphers perturbation gene signatures.
Nan Wang, Peter Langfelder, Matthew Stricos, Lalini Ramanathan, Jeffrey B Richman

Neuron· October 2022

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Accelerated aging with HIV begins at the time of initial HIV infection.
Elizabeth Crabb Breen, Mary E Sehl, Roger Shih, Peter Langfelder, Ruibin Wang

iScience· July 2022

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Uninterrupted CAG repeat drives striatum-selective transcriptionopathy and nuclear pathogenesis in human Huntingtin BAC mice.
Xiaofeng Gu, Jeffrey Richman, Peter Langfelder, Nan Wang, Shasha Zhang

Neuron· April 2022

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Core liver homeostatic co-expression networks are preserved but respond to perturbations in an organism- and disease-specific manner.
Saeed Esmaili, Peter Langfelder, T Grant Belgard, Daniele Vitale, Mahmoud Karimi Azardaryany

Cell Syst· May 2021

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PIAS1 modulates striatal transcription, DNA damage repair, and SUMOylation with relevance to Huntington's disease.
Eva L Morozko, Charlene Smith-Geater, Alejandro Mas Monteys, Subrata Pradhan, Ryan G Lim, Peter Langfelder

Proc Natl Acad Sci U S A· January 2021

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Disease-related Huntingtin seeding activities in cerebrospinal fluids of Huntington's disease patients.
C Y Daniel Lee, Nan Wang, Koning Shen, Matthew Stricos, Peter Langfelder

Sci Rep· November 2020

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Brainwide Genetic Sparse Cell Labeling to Illuminate the Morphology of Neurons and Glia with Cre-Dependent MORF Mice.
Matthew B Veldman, Chang Sin Park, Charles M Eyermann, Jason Y Zhang, Elizabeth Zuniga-Sanchez, Peter Langfelder

Neuron· October 2020

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DNA methylation study of Huntington's disease and motor progression in patients and in animal models.
Ake T Lu, Pritika Narayan, Matthew J Grant, Peter Langfelder, Nan Wang

Nat Commun· September 2020

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No reliable gene expression biomarkers of current or impending neurocognitive impairment in peripheral blood monocytes of persons living with HIV.
Austin Quach, Steve Horvath, Natasha Nemanim, Dimitrios Vatakis, Mallory D Witt, Peter Langfelder

J Neurovirol· June 2018

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A Weighted SNP Correlation Network Method for Estimating Polygenic Risk Scores.
Morgan E Levine, Peter Langfelder, Steve Horvath

Methods Mol Biol· May 2018

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Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer's Disease Models.
C Y Daniel Lee, Anthony Daggett, Xiaofeng Gu, Lu-Lin Jiang, Peter Langfelder

Neuron· March 2018

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MicroRNA signatures of endogenous Huntingtin CAG repeat expansion in mice.
Peter Langfelder, Fuying Gao, Nan Wang, David Howland, Seung Kwak

PLoS One· February 2018

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Titanium biomaterials with complex surfaces induced aberrant peripheral circadian rhythms in bone marrow mesenchymal stromal cells.
Nathaniel Hassan, Kirstin McCarville, Kenzo Morinaga, Cristiane M Mengatto, Peter Langfelder

PLoS One· October 2017

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Exosomes and Homeostatic Synaptic Plasticity Are Linked to Each other and to Huntington's, Parkinson's, and Other Neurodegenerative Diseases by Database-Enabled Analyses of Comprehensively Curated Datasets.
James K T Wang, Peter Langfelder, Steve Horvath, Michael J Palazzolo

Front Neurosci· March 2017

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Huntington's disease accelerates epigenetic aging of human brain and disrupts DNA methylation levels.
Steve Horvath, Peter Langfelder, Seung Kwak, Jeff Aaronson, Jim Rosinski

Aging (Albany NY)· July 2016

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