Publications by authors named "Peter Roach"

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The biochemical dynamics of the glycogen phosphatase laforin directly impact brain metabolism.
M Kathryn Brewer, Katherine J Donohue, Pankaj K Singh, Madushi Raththagala, Zoe R Simmons, Peter J Roach, Anna DePaoli-Roach

J Biol Chem· December 2025

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Subcutaneous drainage of refractory lower limb oedema at the end of life.
Dawn Marie Hooper, Peter Edward Roach

BMJ Case Rep· December 2024

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Lessons learnt from the first two SARS-CoV-2 Omicron waves of the COVID-19 pandemic in six remote Aboriginal and Torres Strait Islander communities in Queensland, Australia: a retrospective epidemiological review.
Allison Hempenstall, Barbara Telfer, Sean Cowley, Shalomie Shadrach, Caroline Taunton, Peter Roach

Med J Aust· October 2024

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Impaired malin expression and interaction with partner proteins in Lafora disease.
Alexander V Skurat, Dyann M Segvich, Christopher J Contreras, Yueh-Chiang Hu, Thomas D Hurley, Anna A DePaoli-Roach, Peter J Roach

J Biol Chem· May 2024

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Integration of metabolic flux with hepatic glucagon signaling and gene expression profiles in the conscious dog.
Katie C Coate, Christopher J Ramnanan, Marta Smith, Jason J Winnick, Guillaume Kraft, Peter J Roach

Am J Physiol Endocrinol Metab· April 2024

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Small-molecule inhibition of glycogen synthase 1 for the treatment of Pompe disease and other glycogen storage disorders.
Julie C Ullman, Kevin T Mellem, Yannan Xi, Vyas Ramanan, Hanne Merritt, Anna A DePaoli-Roach, Peter J Roach

Sci Transl Med· January 2024

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Integration of metabolic flux with hepatic glucagon signaling and gene expression profiles in the conscious dog.
Katie C Coate, Christopher J Ramnanan, Marta Smith, Jason J Winnick, Guillaume Kraft, Peter J Roach

bioRxiv· October 2023

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Dying with behavioral and psychological symptoms of dementia in Australian nursing homes: a retrospective case-control study.
Peter Roach, Melanie R Lovell, Stephen Macfarlane

Front Psychiatry· May 2023

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The structural mechanism of human glycogen synthesis by the GYS1-GYG1 complex.
Nathan M Fastman, Yuxi Liu, Vyas Ramanan, Hanne Merritt, Eileen Ambing, Anna A DePaoli-Roach, Peter J Roach

Cell Rep· July 2022

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Brain glycogen serves as a critical glucosamine cache required for protein glycosylation.
Ramon C Sun, Lyndsay E A Young, Ronald C Bruntz, Kia H Markussen, Zhengqiu Zhou, Anna A DePaoli-Roach, Peter J Roach

Cell Metab· July 2021

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GYS1 or PPP1R3C deficiency rescues murine adult polyglucosan body disease.
Erin E Chown, Peixiang Wang, Xiaochu Zhao, Justin J Crowder, Jordan W Strober, Peter J Roach, Anna A Depaoli-Roach

Ann Clin Transl Neurol· November 2020

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Discovery and Development of Small-Molecule Inhibitors of Glycogen Synthase.
Buyun Tang, Mykhaylo S Frasinyuk, Vimbai M Chikwana, Krishna K Mahalingan, Cynthia A Morgan, Anna A DePaoli-Roach, Peter J Roach

J Med Chem· April 2020

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Glycogenin is Dispensable for Glycogen Synthesis in Human Muscle, and Glycogenin Deficiency Causes Polyglucosan Storage.
Kittichate Visuttijai, Carola Hedberg-Oldfors, Christer Thomsen, Emma Glamuzina, Cornelia Kornblum, Peter Roach

J Clin Endocrinol Metab· February 2020

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Accurate and sensitive quantitation of glucose and glucose phosphates derived from storage carbohydrates by mass spectrometry.
Lyndsay E A Young, Corey O Brizzee, Jessica K A Macedo, Robert D Murphy, Christopher J Contreras, Anna A DePaoli-Roach, Peter J Roach

Carbohydr Polym· February 2020

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Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation.
Alicia Mayeuf-Louchart, Steve Lancel, Yasmine Sebti, Benoit Pourcet, Anne Loyens, Peter J Roach

Cell Rep· November 2019

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Targeting Pathogenic Lafora Bodies in Lafora Disease Using an Antibody-Enzyme Fusion.
M Kathryn Brewer, Annette Uittenbogaard, Grant L Austin, Dyann M Segvich, Anna DePaoli-Roach, Peter J Roach

Cell Metab· October 2019

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Lafora disease offers a unique window into neuronal glycogen metabolism.
Matthew S Gentry, Joan J Guinovart, Berge A Minassian, Peter J Roach, Jose M Serratosa

J Biol Chem· May 2018

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Substrate recognition and mechanism revealed by ligand-bound polyphosphate kinase 2 structures.
Alice E Parnell, Silja Mordhorst, Florian Kemper, Mariacarmela Giurrandino, Josh P Prince, Peter L Roach

Proc Natl Acad Sci U S A· March 2018

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Whole genome transcriptomics reveals global effects including up-regulation of Francisella pathogenicity island gene expression during active stringent response in the highly virulent Francisella tularensis subsp. tularensis SCHU S4.
Amber L Murch, Paul J Skipp, Peter L Roach, Petra C F Oyston

Microbiology (Reading)· November 2017

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Lack of liver glycogen causes hepatic insulin resistance and steatosis in mice.
Jose M Irimia, Catalina M Meyer, Dyann M Segvich, Sneha Surendran, Anna A DePaoli-Roach, Peter J Roach

J Biol Chem· June 2017

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Novel method for detection of glycogen in cells.
Alexander V Skurat, Dyann M Segvich, Anna A DePaoli-Roach, Peter J Roach

Glycobiology· May 2017

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Redox Switch for the Inhibited State of Yeast Glycogen Synthase Mimics Regulation by Phosphorylation.
Krishna K Mahalingan, Sulochanadevi Baskaran, Anna A DePaoli-Roach, Peter J Roach, Thomas D Hurley

Biochemistry· January 2017

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Metallocofactor assembly for [FeFe]-hydrogenases.
Pedro Dinis, Beata M Wieckowski, Peter L Roach

Curr Opin Struct Biol· December 2016

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Gain of function AMP-activated protein kinase γ3 mutation (AMPKγ3R200Q) in pig muscle increases glycogen storage regardless of AMPK activation.
Tracy L Scheffler, Sungkwon Park, Peter J Roach, David E Gerrard

Physiol Rep· June 2016

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Incorporation of phosphate into glycogen by glycogen synthase.
Christopher J Contreras, Dyann M Segvich, Krishna Mahalingan, Vimbai M Chikwana, Terence L Kirley, Anna A DePaoli-Roach, Peter J Roach

Arch Biochem Biophys· May 2016

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