Publications by authors named "Peter W Hamilton"

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Validation of the systematic scoring of immunohistochemically stained tumour tissue microarrays using QuPath digital image analysis.
Maurice B Loughrey, Peter Bankhead, Helen G Coleman, Ryan S Hagan, Stephanie Craig, Peter W Hamilton

Histopathology· August 2018

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Integrated tumor identification and automated scoring minimizes pathologist involvement and provides new insights to key biomarkers in breast cancer.
Peter Bankhead, José A Fernández, Darragh G McArt, David P Boyle, Gerald Li, Peter W Hamilton

Lab Invest· January 2018

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QuPath: Open source software for digital pathology image analysis.
Peter Bankhead, Maurice B Loughrey, José A Fernández, Yvonne Dombrowski, Darragh G McArt, Peter W Hamilton

Sci Rep· December 2017

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Connectivity Mapping for Candidate Therapeutics Identification Using Next Generation Sequencing RNA-Seq Data.
Darragh G McArt, Philip D Dunne, Jaine K Blayney, Manuel Salto-Tellez, Sandra Van Schaeybroeck, Peter W Hamilton

PLoS One· October 2017

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IHC-based subcellular quantification provides new insights into prognostic relevance of FLIP and procaspase-8 in non-small-cell lung cancer.
Ryan A Hutchinson, Helen G Coleman, Kathy Gately, Vincent Young, Siobhan Nicholson, Peter W Hamilton

Cell Death Discov· August 2017

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Embracing an integromic approach to tissue biomarker research in cancer: Perspectives and lessons learned.
Gerald Li, Peter Bankhead, Philip D Dunne, Paul G O'Reilly, Jacqueline A James, Peter W Hamilton

Brief Bioinform· July 2017

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Statin use, candidate mevalonate pathway biomarkers, and colon cancer survival in a population-based cohort study.
Ronan T Gray, Maurice B Loughrey, Peter Bankhead, Chris R Cardwell, Stephen McQuaid, Peter W Hamilton

Br J Cancer· June 2017

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Evaluation of PTGS2 Expression, PIK3CA Mutation, Aspirin Use and Colon Cancer Survival in a Population-Based Cohort Study.
Ronan T Gray, Marie M Cantwell, Helen G Coleman, Maurice B Loughrey, Peter Bankhead, Peter W Hamilton

Clin Transl Gastroenterol· April 2017

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KRAS mutant colorectal cancer gene signatures identified angiotensin II receptor blockers as potential therapies.
Qing Wen, Philip D Dunne, Paul G O'Reilly, Gerald Li, Anthony J Bjourson, Peter W Hamilton

Oncotarget· January 2017

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Building a 'Repository of Science': The importance of integrating biobanks within molecular pathology programmes.
Claire Lewis, Stephen McQuaid, Peter W Hamilton, Manuel Salto-Tellez, Darragh McArt

Eur J Cancer· November 2016

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Challenging the Cancer Molecular Stratification Dogma: Intratumoral Heterogeneity Undermines Consensus Molecular Subtypes and Potential Diagnostic Value in Colorectal Cancer.
Philip D Dunne, Darragh G McArt, Conor A Bradley, Paul G O'Reilly, Helen L Barrett, Peter W Hamilton

Clin Cancer Res· August 2016

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QUADrATiC: scalable gene expression connectivity mapping for repurposing FDA-approved therapeutics.
Paul G O'Reilly, Qing Wen, Peter Bankhead, Philip D Dunne, Darragh G McArt, Peter W Hamilton

BMC Bioinformatics· May 2016

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A gene-signature progression approach to identifying candidate small-molecule cancer therapeutics with connectivity mapping.
Qing Wen, Chang-Sik Kim, Peter W Hamilton, Shu-Dong Zhang

BMC Bioinformatics· May 2016

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Delivering a research-enabled multistakeholder partnership for enhanced patient care at a population level: The Northern Ireland Comprehensive Cancer Program.
Mark Lawler, Anna Gavin, Manuel Salto-Tellez, Richard D Kennedy, Sandra Van Schaeybroeck, Peter W Hamilton

Cancer· March 2016

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Whole slide image cytometry: a novel method to detect abnormal DNA content in Barrett's esophagus.
Yinhai Wang, Damian T McManus, Kenneth Arthur, Brian T Johnston, Andrew J Kennedy, Peter W Hamilton

Lab Invest· November 2015

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Automated tumor analysis for molecular profiling in lung cancer.
Peter W Hamilton, Yinhai Wang, Clinton Boyd, Jacqueline A James, Maurice B Loughrey

Oncotarget· September 2015

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Digital slide viewing for primary reporting in gastrointestinal pathology: a validation study.
Maurice B Loughrey, Paul J Kelly, Oisin P Houghton, Helen G Coleman, Joseph P Houghton, Peter W Hamilton

Virchows Arch· August 2015

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Comprehensive molecular pathology analysis of small bowel adenocarcinoma reveals novel targets with potential for clinical utility.
Muhammad A Alvi, Darragh G McArt, Paul Kelly, Marc-Aurel Fuchs, Matthew Alderdice, Peter W Hamilton

Oncotarget· August 2015

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Epidermal growth factor receptor immunohistochemistry: new opportunities in metastatic colorectal cancer.
Ryan A Hutchinson, Richard A Adams, Darragh G McArt, Manuel Salto-Tellez, Bharat Jasani, Peter W Hamilton

J Transl Med· July 2015

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PICan: An integromics framework for dynamic cancer biomarker discovery.
Darragh G McArt, Jaine K Blayney, David P Boyle, Gareth W Irwin, Michael Moran, Peter W Hamilton

Mol Oncol· June 2015

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Concordance between digital pathology and light microscopy in general surgical pathology: a pilot study of 100 cases.
Joseph P Houghton, Aaron J Ervine, Sarah L Kenny, Paul J Kelly, Seamus S Napier, Peter W Hamilton

J Clin Pathol· December 2014

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Digital pathology and image analysis in tissue biomarker research.
Peter W Hamilton, Peter Bankhead, Yinhai Wang, Ryan Hutchinson, Declan Kieran

Methods· November 2014

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Molecular pathology - the value of an integrative approach.
Manuel Salto-Tellez, Jacqueline A James, Peter W Hamilton

Mol Oncol· October 2014

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The prognostic significance of the aberrant extremes of p53 immunophenotypes in breast cancer.
David P Boyle, Darragh G McArt, Gareth Irwin, Charlotte S Wilhelm-Benartzi, Tong F Lioe, Peter W Hamilton

Histopathology· September 2014

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Virtual microscopy and digital pathology in training and education.
Peter W Hamilton, Yinhai Wang, Stephen J McCullough

APMIS· April 2012

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