Publications by authors named "Petra Goelzer"

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Characterization of the transmembrane transport and absolute bioavailability of the HCV protease inhibitor danoprevir.
Barbara J Brennan, Agnès Poirier, Sebastian Moreira, Peter N Morcos, Petra Goelzer

Clin Pharmacokinet· May 2015

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Single-dose pharmacokinetics of the HCV polymerase inhibitor mericitabine in healthy Caucasian and Japanese subjects.
Carla Washington, Sebastian Moreira, Joshua Haznedar, Petra Goelzer, Ya-Chi Chen

Drug Metab Pharmacokinet· December 2014

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Embryofetal development study of vismodegib, a hedgehog pathway inhibitor, in rats.
Eric Morinello, Michael Pignatello, Loris Villabruna, Petra Goelzer, Heinrich Bürgin

Birth Defects Res B Dev Reprod Toxicol· April 2014

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Preparation and characterization of albumin conjugates of a truncated peptide YY analogue for half-life extension.
George K Ehrlich, Hanspeter Michel, Theresa Truitt, William Riboulet, Petar Pop-Damkov, Petra Goelzer

Bioconjug Chem· December 2013

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Pharmacokinetics of a three-way drug interaction between danoprevir, ritonavir and the organic anion transporting polypeptide (OATP) inhibitor ciclosporin.
Barbara J Brennan, Sebastian A Moreira, Peter N Morcos, Mercidita T Navarro, Jiney Asthappan, Petra Goelzer

Clin Pharmacokinet· September 2013

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The safety, tolerability, pharmacokinetics, and pharmacodynamics of single oral doses of RO5068760, an MEK inhibitor, in healthy volunteers: assessment of target suppression.
Lucy Lee, Huifeng Niu, Petra Goelzer, Ruediger Rueger, Jonathan Deutsch

J Clin Pharmacol· December 2010

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Preclinical in vivo evaluation of efficacy, pharmacokinetics, and pharmacodynamics of a novel MEK1/2 kinase inhibitor RO5068760 in multiple tumor models.
Sherif Daouti, Brian Higgins, Kenneth Kolinsky, Kathryn Packman, Huisheng Wang, Petra Goelzer

Mol Cancer Ther· January 2010

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The safety, tolerability, pharmacokinetics, and pharmacodynamics of single oral doses of CH4987655 in healthy volunteers: target suppression using a biomarker.
Lucy Lee, Huifeng Niu, Ruediger Rueger, Yuriko Igawa, Jonathan Deutsch, Petra Goelzer

Clin Cancer Res· December 2009

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Discovery of [4-Amino-2-(1-methanesulfonylpiperidin-4-ylamino)pyrimidin-5-yl](2,3-difluoro-6- methoxyphenyl)methanone (R547), a potent and selective cyclin-dependent kinase inhibitor with significant in vivo antitumor activity.
Xin-Jie Chu, Wanda DePinto, David Bartkovitz, Sung-Sau So, Binh T Vu, Petra Goelzer

J Med Chem· November 2006

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In vitro and in vivo activity of R547: a potent and selective cyclin-dependent kinase inhibitor currently in phase I clinical trials.
Wanda DePinto, Xin-Jie Chu, Xuefeng Yin, Melissa Smith, Kathryn Packman, Petra Goelzer

Mol Cancer Ther· November 2006

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Microsome-mediated oxidation of N-nitrosodiethanolamine (NDELA), a bident carcinogen.
Richard N Loeppky, Petra Goelzer

Chem Res Toxicol· April 2002

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DNA adducts from N-nitrosodiethanolamine and related beta-oxidized nitrosamines in vivo: (32)P-postlabeling methods for glyoxal- and O(6)-hydroxyethyldeoxyguanosine adducts.
Richard N Loeppky, Qiuping Ye, Petra Goelzer, Yuen Chen

Chem Res Toxicol· April 2002

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