Publications by authors named "Philip D Butcher"

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Xpert MTB/RIF® cycle threshold as a marker of TB disease severity; Implications for TB treatment stratification.
Daniel J Grint, Jasvir Dhillon, Philip D Butcher, Jack Adams, Tulika Munshi

Clin Infect Dis· September 2025

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Four-Month High-Dose Rifampicin Regimens for Pulmonary Tuberculosis.
Amina Jindani, Daniel Atwine, Daniel Grint, Boubacar Bah, Jack Adams, Philip D Butcher

NEJM Evid· September 2023

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A Novel Microfluidic Dielectrophoresis Technology to Enable Rapid Diagnosis of Mycobacteria tuberculosis in Clinical Samples.
Catherine M Moore, Jasvir Dhillon, Rebecca Flynn, Krzysztof Gizynski, Candice Adams, Philip D Butcher

J Mol Diagn· July 2023

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An integrated whole genome analysis of Mycobacterium tuberculosis reveals insights into relationship between its genome, transcriptome and methylome.
Paula J Gomez-Gonzalez, Nuria Andreu, Jody E Phelan, Paola Florez de Sessions, Judith R Glynn, Philip D Butcher

Sci Rep· March 2019

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Drug resistant TB: UK multicentre study (DRUMS): Treatment, management and outcomes in London and West Midlands 2008-2014.
Amber Arnold, Graham S Cooke, Onn Min Kon, Martin Dedicoat, Marc Lipman, Philip D Butcher

J Infect· March 2017

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Use of whole-genome sequencing to distinguish relapse from reinfection in a completed tuberculosis clinical trial.
Adam A Witney, Anna L E Bateson, Amina Jindani, Patrick P J Phillips, David Coleman, Philip D Butcher

BMC Med· March 2017

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XDR-TB transmission in London: Case management and contact tracing investigation assisted by early whole genome sequencing.
Amber Arnold, Adam A Witney, Stephania Vergnano, Anita Roche, Catherine A Cosgrove, Philip D Butcher

J Infect· September 2016

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Accurate detection of Neisseria gonorrhoeae ciprofloxacin susceptibility directly from genital and extragenital clinical samples: towards genotype-guided antimicrobial therapy.
Marcus J Pond, Catherine L Hall, Victoria F Miari, Michelle Cole, Ken G Laing, Philip D Butcher

J Antimicrob Chemother· April 2016

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Profiling persistent tubercule bacilli from patient sputa during therapy predicts early drug efficacy.
Isobella Honeyborne, Timothy D McHugh, Iitu Kuittinen, Anna Cichonska, Dimitrios Evangelopoulos, Philip D Butcher

BMC Med· April 2016

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Clinical use of whole genome sequencing for Mycobacterium tuberculosis.
Adam A Witney, Catherine A Cosgrove, Amber Arnold, Jason Hinds, Neil G Stoker, Philip D Butcher

BMC Med· March 2016

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Performance evaluation of automated urine microscopy as a rapid, non-invasive approach for the diagnosis of non-gonococcal urethritis.
Marcus J Pond, Achyuta V Nori, Sheel Patel, Ken Laing, Margarita Ajayi, Philip D Butcher

Sex Transm Infect· May 2015

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Clinical application of whole-genome sequencing to inform treatment for multidrug-resistant tuberculosis cases.
Adam A Witney, Katherine A Gould, Amber Arnold, David Coleman, Rachel Delgado, Philip D Butcher

J Clin Microbiol· May 2015

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Potassium availability triggers Mycobacterium tuberculosis transition to, and resuscitation from, non-culturable (dormant) states.
Elena G Salina, Simon J Waddell, Nadine Hoffmann, Ida Rosenkrands, Philip D Butcher

Open Biol· October 2014

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High-dose rifapentine with moxifloxacin for pulmonary tuberculosis.
Amina Jindani, Thomas S Harrison, Andrew J Nunn, Patrick P J Phillips, Gavin J Churchyard, Philip D Butcher

N Engl J Med· October 2014

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Evidence for a role for interleukin-17, Th17 cells and iron homeostasis in protective immunity against tuberculosis in cynomolgus macaques.
Alice S Wareham, Julia A Tree, Philip D Marsh, Philip D Butcher, Mike Dennis

PLoS One· September 2014

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Oleoyl coenzyme A regulates interaction of transcriptional regulator RaaS (Rv1219c) with DNA in mycobacteria.
Obolbek Turapov, Simon J Waddell, Bernard Burke, Sarah Glenn, Asel A Sarybaeva, Philip D Butcher

J Biol Chem· September 2014

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Antimicrobial treatment improves mycobacterial survival in nonpermissive growth conditions.
Obolbek Turapov, Simon J Waddell, Bernard Burke, Sarah Glenn, Asel A Sarybaeva, Philip D Butcher

Antimicrob Agents Chemother· May 2014

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High prevalence of antibiotic-resistant Mycoplasma genitalium in nongonococcal urethritis: the need for routine testing and the inadequacy of current treatment options.
Marcus J Pond, Achyuta V Nori, Adam A Witney, Rose C Lopeman, Philip D Butcher

Clin Infect Dis· March 2014

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BμG@Sbase--a microbial gene expression and comparative genomic database.
Adam A Witney, Denise E Waldron, Lucy A Brooks, Richard H Tyler, Michael Withers, Philip D Butcher

Nucleic Acids Res· January 2012

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Methionine sulfoximine resistance in Mycobacterium tuberculosis is due to a single nucleotide deletion resulting in increased expression of the major glutamine synthetase, GlnA1.
Paul Carroll, Simon J Waddell, Philip D Butcher, Tanya Parish

Microb Drug Resist· September 2011

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Mycobacterial p(1)-type ATPases mediate resistance to zinc poisoning in human macrophages.
Hélène Botella, Pascale Peyron, Florence Levillain, Renaud Poincloux, Yannick Poquet, Philip D Butcher

Cell Host Microbe· September 2011

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Examining the basis of isoniazid tolerance in nonreplicating Mycobacterium tuberculosis using transcriptional profiling.
Griselda Tudó, Ken Laing, Denis A Mitchison, Philip D Butcher, Simon J Waddell

Future Med Chem· August 2010

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Use of DNA arrays to study transcriptional responses to antimycobacterial compounds.
Simon J Waddell, Philip D Butcher

Methods Mol Biol· July 2010

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Contrasting transcriptional responses of a virulent and an attenuated strain of Mycobacterium tuberculosis infecting macrophages.
Alice H Li, Simon J Waddell, Jason Hinds, Chad A Malloff, Manjeet Bains, Philip D Butcher

PLoS One· June 2010

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Professor D A Mitchison: 60 years of contributions to the chemotherapy of tuberculosis.
Philip D Butcher, Amina Jindani

Tuberculosis (Edinb)· May 2010

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