Publications by authors named "Philip Pitis"

Claim this Profile
P
PRT3789 is a First-in-Human SMARCA2-Selective Degrader that Induces Synthetic Lethality in SMARCA4-Mutated Cancers.
Michael Hulse, Min Wang, Chaoyi Xu, Jack Carter, Anjana Agarwal, Philip Pitis

Cancer Res· September 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Dysregulation of PRMT5 in chronic lymphocytic leukemia promotes progression with high risk of Richter's transformation.
Zachary A Hing, Janek S Walker, Ethan C Whipp, Lindsey Brinton, Matthew Cannon, Philip Pitis

Nat Commun· January 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structure-activity relationships and discovery of a G protein biased μ opioid receptor ligand, [(3-methoxythiophen-2-yl)methyl]({2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro-[4.5]decan-9-yl]ethyl})amine (TRV130), for the treatment of acute severe pain.
Xiao-Tao Chen, Philip Pitis, Guodong Liu, Catherine Yuan, Dimitar Gotchev

J Med Chem· October 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A G protein-biased ligand at the μ-opioid receptor is potently analgesic with reduced gastrointestinal and respiratory dysfunction compared with morphine.
Scott M DeWire, Dennis S Yamashita, David H Rominger, Guodong Liu, Conrad L Cowan, Philip M Pitis

J Pharmacol Exp Ther· March 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Parallel methods for the preparation and SAR exploration of N-ethyl-4-[(8-alkyl-8-aza-bicyclo[3.2.1]oct-3-ylidene)-aryl-methyl]-benzamides, powerful mu and delta opioid agonists.
Steven J Coats, Mark J Schulz, John R Carson, Ellen E Codd, Dennis J Hlasta, Philip M Pitis

Bioorg Med Chem Lett· November 2004

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
N,N-dialkyl-4-[(8-azabicyclo[3.2.1]-oct-3-ylidene)phenylmethyl]benzamides, potent, selective delta opioid agonists.
John R Carson, Steven J Coats, Ellen E Codd, Scott L Dax, Jung Lee, Philip M Pitis

Bioorg Med Chem Lett· May 2004

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
N-alkyl-4-[(8-azabicyclo[3.2.1]-oct-3-ylidene)phenylmethyl]benzamides, micro and delta opioid agonists: a micro address.
John R Carson, Steven J Coats, Ellen E Codd, Scott L Dax, Jung Lee, Philip M Pitis

Bioorg Med Chem Lett· May 2004

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis